DegronMD - Q7Z6E9(RBBP6)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G165C	TCGA-05-4396	LUAD	TCGA	PPSY	ITCH	156:159	Mutation rewiring degron network	0.1667
p.G165C	DO229008	LICA	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.1667
p.G165C	DO23838	LUAD	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.1667
p.R1182C	TCGA-06-5416	GBM	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.R1182C	DO10880	GBM	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.I1034T	TCGA-12-0657	GBM	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.5966
p.I1034T	DO13911	GBM	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.5966
p.P154S	TCGA-18-3409	LUSC	TCGA	PPSY	ITCH	156:159	Mutation rewiring degron network	0.2778
p.P154S	DO26444	LUSC	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.2778
p.D1024N	TCGA-37-3792	LUSC	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1667
p.D1024N	DO27192	LUSC	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1667
p.V816I	TCGA-44-3918	LUAD	TCGA	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.V816I	DO23732	LUAD	ICGC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R430W	TCGA-44-8119	LUAD	TCGA	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1389
p.R430W	TCGA-GN-A266	SKCM	TCGA	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1389
p.R430W	DO24399	LUAD	ICGC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1389
p.R430W	DO37432	SKCM	ICGC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1389
p.W615C	TCGA-51-6867	LUSC	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.5889
p.W615C	DO26477	LUSC	ICGC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.5889
p.P563L	TCGA-56-7582	LUSC	TCGA	PPLY	ITCH	562:565	Mutation altering degron motif	0.7582
p.P563L	DO26976	LUSC	ICGC	PPLY	ITCH	562:565	Mutation altering degron motif	0.7582
p.R91Q	TCGA-A5-A2K5	UCEC	TCGA	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1389
p.R91Q	DO41379	UCEC	ICGC	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1389
p.R91Q	SIDM01588	Endometrial Carcinoma	GDSC	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1389
p.R91Q	ACH-000993	Endometrial/Uterine Cancer	CCLE	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1389
p.A1204V	TCGA-AG-3892	READ	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.A1204V	TCGA-IB-7651	PAAD	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.A1204V	DO46657	PAAD	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.A1204V	DO36394	READ	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.A1204V	SIDM01617	Endometrial Carcinoma	GDSC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.A1204V	ACH-000994	Endometrial/Uterine Cancer	CCLE	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1389
p.R1021Q	TCGA-AJ-A3EL	UCEC	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.0833
p.R1021Q	TCGA-D1-A1NZ	UCEC	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.0833
p.R1021Q	DO41542	UCEC	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.0833
p.R1021Q	DO41536	UCEC	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.0833
p.K1199T	TCGA-AJ-A3EL	UCEC	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2778
p.K1199T	DO41542	UCEC	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2778
p.G153R	TCGA-AN-A0FV	BRCA	TCGA	PPSY	ITCH	156:159	Mutation rewiring degron network	0.25
p.G153R	DO5284	BRCA	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.25
p.P1180A	TCGA-B0-4698	KIRC	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.0556
p.P1180A	DO20368	KIRC	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.0556
p.G1025E	TCGA-B5-A3FC	UCEC	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.G1025E	DO41871	UCEC	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.L369P	TCGA-BS-A0UJ	UCEC	TCGA	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.25
p.L369P	DO42745	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.25
p.N1033S	TCGA-C8-A3M7	BRCA	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7069
p.N1033S	DO44133	BRCA	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7069
p.R793H	TCGA-CM-5348	COAD	TCGA	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R793H	DO9514	COAD	ICGC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R793H	SIDM01121	Small Cell Lung Carcinoma	GDSC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R793H	NCI-H69	lung	COSMIC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R163H	TCGA-CN-6995	HNSC	TCGA	PPSY	ITCH	156:159	Mutation rewiring degron network	0.2222
p.R163H	DO14854	HNSC	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.2222
p.P805Q	TCGA-D3-A2J6	SKCM	TCGA	PPPY	ITCH	803:806	Mutation altering degron motif	0.5924
p.P805Q	DO37901	SKCM	ICGC	PPPY	ITCH	803:806	Mutation altering degron motif	0.5924
p.P602S	TCGA-D3-A2JF	SKCM	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.0833
p.P602S	DO38153	SKCM	ICGC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.0833
p.K166E	TCGA-D5-6530	COAD	TCGA	PPSY	ITCH	156:159	Mutation substituting flanking lysine	0.25
p.K166E	DO8312	COAD	ICGC	PPSY	ITCH	156:159	Mutation substituting flanking lysine	0.25
p.P1037H	TCGA-DU-6392	LGG	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.25
p.P1037H	DO22237	LGG	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.25
p.P382S	TCGA-EB-A97M	SKCM	TCGA	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.1667
p.P382S	DO50298	SKCM	ICGC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.1667
p.R1419M	TCGA-EE-A20F	SKCM	TCGA	EKENP	DEG_APCC_KENBOX_2	1412:1416	Mutation rewiring degron network	0.25
p.R1419M	DO37961	SKCM	ICGC	EKENP	DEG_APCC_KENBOX_2	1412:1416	Mutation rewiring degron network	0.25
p.P575S	TCGA-EE-A3JE	SKCM	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.P575S	TCGA-FS-A1ZP	SKCM	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.P575S	DO37703	SKCM	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.P575S	DO48766	SKCM	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.G813W	TCGA-ER-A1A1	SKCM	TCGA	PPPY	ITCH	803:806	Mutation rewiring degron network	0.1389
p.G813W	DO37413	SKCM	ICGC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.1389
p.S1201Y	TCGA-EY-A1GI	UCEC	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2222
p.S1201Y	TCGA-F5-6814	READ	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2222
p.S1201Y	DO36556	READ	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2222
p.S1201Y	DO41211	UCEC	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.2222
p.T160M	TCGA-F1-A448	STAD	TCGA	PPSY	ITCH	156:159	Mutation rewiring degron network	0.3056
p.T160M	DO48044	STAD	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.3056
p.T160M	SIDM01664	Prostate Carcinoma	GDSC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.3056
p.T160M	ACH-000952	Prostate Cancer	CCLE	PPSY	ITCH	156:159	Mutation rewiring degron network	0.3056
p.V555G	TCGA-F7-7848	HNSC	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1389
p.V555G	DO14198	HNSC	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1389
p.R1182H	TCGA-FI-A2D5	UCEC	TCGA	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.R1182H	DO41331	UCEC	ICGC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.R1182H	SIDM00529	Breast Carcinoma	GDSC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.R1182H	SIDM00068	Colorectal Carcinoma	GDSC	KMDRTPEK	DEG_SCF_SKP2-CKS1_1	1190:1197	Mutation rewiring degron network	0.1111
p.P573S	TCGA-FW-A3R5	SKCM	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.P573S	TCGA-W3-AA1R	SKCM	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.P573S	DO37406	SKCM	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.P573S	DO51275	SKCM	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.P575L	TCGA-FW-A3R5	SKCM	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.P575L	DO37406	SKCM	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0556
p.P566S	TCGA-G2-A2EC	BLCA	TCGA	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P566S	DO651	BLCA	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.S617L	TCGA-GF-A3OT	SKCM	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7667
p.S617L	DO47288	SKCM	ICGC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7667
p.S617L	SIDM00298	Squamous Cell Lung Carcinoma	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7667
p.S617L	ACH-000705	Lung Cancer	CCLE	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7667
p.S617L	ACH-001113	Lung Cancer	CCLE	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7667
p.T613A	TCGA-L5-A4OI	ESCA	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.7139
p.N1023I	TCGA-MH-A55W	KIRP	TCGA	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1389
p.N1023I	DO48516	KIRP	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1389
p.P605S	TCGA-QB-A6FS	SKCM	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1667
p.P605S	DO48654	SKCM	ICGC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1667
p.A623T	TCGA-SJ-A6ZI	UCEC	TCGA	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1667
p.A623T	DO219784	UCEC	ICGC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1667
p.K1022N	DO224732	BRCA	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation substituting flanking lysine	0.2222
p.E1032G	DO222834	BTCA	ICGC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7199
p.V416L	DO229005	COCA	ICGC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.2778
p.V416L	DO35100	PACA	ICGC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.2778
p.Y565F	DO228299	LICA	ICGC	PPLY	ITCH	562:565	Mutation altering degron motif	0.7528
p.V557L	DO229019	LICA	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1944
p.G153C	DO229026	LICA	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.25
p.R163L	DO229037	LICA	ICGC	PPSY	ITCH	156:159	Mutation rewiring degron network	0.2222
p.P1416R	DO50782	LICA	ICGC	EKENP	DEG_APCC_KENBOX_2	1412:1416	Mutation altering degron motif	0.6401
p.T553A	DO23527	LIRI	ICGC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.0833
p.T86S	DO52694	MALY	ICGC	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation blocking phosphorylation signal	0.7222
p.K1418N	DO229453	SKCA	ICGC	EKENP	DEG_APCC_KENBOX_2	1412:1416	Mutation rewiring degron network	0.2778
p.L369F	DO229456	SKCA	ICGC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.25
p.I71V	SIDM01954	Colorectal Carcinoma	GDSC	VKSTS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.0833
p.M370T	SIDM01004	Chronic Myelogenous Leukemia	GDSC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.2778
p.M370T	ACH-000983	Leukemia	CCLE	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.2778
p.M370T	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.2778
p.V409G	SIDM00434	Plasma Cell Myeloma	GDSC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0833
p.V409G	ACH-000745	Myeloma	CCLE	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0833
p.V409G	MOLP-8	haematopoietic and lymphoid tissue	COSMIC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0833
p.S363P	SIDM00340	Plasma Cell Myeloma	GDSC	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation blocking phosphorylation signal	0.5278
p.L611I	SIDM00845	Burkitt's Lymphoma	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.6063
p.L611I	SIDM00461	Acute Myeloid Leukemia	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.6063
p.L611I	SIDM01519	Head and Neck Carcinoma	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.6063
p.L611I	Daudi	haematopoietic and lymphoid tissue	COSMIC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation altering degron motif	0.6063
p.P428R	SIDM00853	Other Sarcomas	GDSC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1944
p.P428R	ACH-000835	Sarcoma	CCLE	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1944
p.P428R	GCT	soft tissue	COSMIC	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1944
p.Y799C	SIDM00487	Colorectal Carcinoma	GDSC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.2222
p.Y799C	ACH-000963	Colon/Colorectal Cancer	CCLE	PPPY	ITCH	803:806	Mutation rewiring degron network	0.2222
p.Y799C	CCK-81	large intestine	COSMIC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.2222
p.G603W	SIDM00143	Small Cell Lung Carcinoma	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1111
p.G603W	ACH-000803	Lung Cancer	CCLE	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1111
p.G603W	COLO-668	lung	COSMIC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1111
p.R793C	SIDM00214	Colorectal Carcinoma	GDSC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R793C	ACH-000955	Colon/Colorectal Cancer	CCLE	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.R793C	SNU-407	large intestine	COSMIC	PPPY	ITCH	803:806	Mutation rewiring degron network	0.0556
p.H624Y	SIDM00240	Cervical Carcinoma	GDSC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1389
p.H624Y	OMC-1	cervix	COSMIC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.1389
p.P561Q	SIDM00077	Oral Cavity Carcinoma	GDSC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P561Q	ACH-001331	Head and Neck Cancer	CCLE	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P561Q	BICR10	upper aerodigestive tract	COSMIC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P567S	SIDM01608	Endometrial Carcinoma	GDSC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.2778
p.P567S	ACH-000990	Endometrial/Uterine Cancer	CCLE	PPLY	ITCH	562:565	Mutation rewiring degron network	0.2778
p.P566L	SIDM01424	B-Lymphoblastic Leukemia	GDSC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P566L	ACH-000782	Leukemia	CCLE	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.P566L	ACH-001735	Leukemia	CCLE	PPLY	ITCH	562:565	Mutation rewiring degron network	0.3056
p.S363L	ACH-000575	Lung Cancer	CCLE	PVTSS	DEG_SPOP_SBC_1	372:376	Mutation blocking phosphorylation signal	0.5278
p.P554T	ACH-000586	Lung Cancer	CCLE	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.P554T	NCI-H1876	lung	COSMIC	PPLY	ITCH	562:565	Mutation rewiring degron network	0.1111
p.V416A	ACH-001610	Brain Cancer	CCLE	ISVHSE	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.2778
p.R620C	HT-115	large intestine	COSMIC	LSTPWVS	DEG_SCF_FBW7_1	611:617	Mutation rewiring degron network	0.25
p.R1426C	HT-115	large intestine	COSMIC	EKENP	DEG_APCC_KENBOX_2	1412:1416	Mutation rewiring degron network	0.0556
p.T1032I	SUIT-2	pancreas	COSMIC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7078
p.S1044Y	CAL-72	bone	COSMIC	KKENI	DEG_APCC_KENBOX_2	1030:1034	Mutation substituting flanking lysine	0.1667
p.D805G	EN	endometrium	COSMIC	PPPY	ITCH	803:806	Mutation altering degron motif	0.7198

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RBBP6

UniProt ID: Q7Z6E9

Entrez ID: 5930

Protein name: E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RBBP6 in