DegronMD - Q9BVV6(KIAA0586)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R397H	TCGA-17-Z045	LUAD	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.8244
p.S342F	TCGA-33-6737	LUSC	TCGA	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.0833
p.S342F	TCGA-85-8354	LUSC	TCGA	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.0833
p.S342F	DO26866	LUSC	ICGC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.0833
p.S342F	DO45467	LUSC	ICGC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.0833
p.R397L	TCGA-34-7107	LUSC	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.8428
p.R397L	DO26449	LUSC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.8428
p.R1077T	TCGA-98-A538	LUSC	TCGA	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.0556
p.D1033A	TCGA-A5-A1OF	UCEC	TCGA	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation rewiring degron network	0.25
p.D1033A	TCGA-A5-A1OF	UCEC	TCGA	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.0556
p.P1101L	TCGA-A5-A1OF	UCEC	TCGA	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation altering degron motif	0.7582
p.A1042T	TCGA-A5-A2K7	UCEC	TCGA	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.7139
p.A1042T	TCGA-IB-7651	PAAD	TCGA	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.7139
p.A1042T	TCGA-UY-A8OC	BLCA	TCGA	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.7139
p.A1042T	SIDM02059	Colorectal Carcinoma	GDSC	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.7139
p.A1067T	TCGA-AA-3864	COAD	TCGA	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation altering degron motif	0.7139
p.D1048V	TCGA-AD-6899	COAD	TCGA	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation altering degron motif	0.7785
p.R709Q	TCGA-AG-A002	READ	TCGA	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	TCGA-B5-A0JY	UCEC	TCGA	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	TCGA-D1-A16X	UCEC	TCGA	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	TCGA-D1-A17Q	UCEC	TCGA	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	SIDM00118	Colorectal Carcinoma	GDSC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	ACH-001081	Colon/Colorectal Cancer	CCLE	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.R709Q	HCC2998	large intestine	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.T1114M	TCGA-AP-A0LD	UCEC	TCGA	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.7423
p.T1114M	DO41578	UCEC	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.7423
p.P390H	TCGA-AX-A2HC	UCEC	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P390H	DO41572	UCEC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.D694Y	TCGA-B5-A11E	UCEC	TCGA	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.1111
p.R344G	TCGA-BG-A222	UCEC	TCGA	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation substituting flanking lysine	0.25
p.R344G	DO42977	UCEC	ICGC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation substituting flanking lysine	0.25
p.S1090F	TCGA-CJ-4638	KIRC	TCGA	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1944
p.P390L	TCGA-CV-7568	HNSC	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P390L	TCGA-EE-A29D	SKCM	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P390L	DO14160	HNSC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P390L	DO38123	SKCM	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P1109L	TCGA-D3-A5GU	SKCM	TCGA	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109L	TCGA-D3-A5GU	SKCM	TCGA	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1109L	DO47584	SKCM	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109L	DO47584	SKCM	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1116L	TCGA-EB-A431	SKCM	TCGA	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.7582
p.P1116L	DO37671	SKCM	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.7582
p.P390S	TCGA-EB-A85J	SKCM	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P390S	DO50297	SKCM	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2222
p.P1052S	TCGA-EE-A29L	SKCM	TCGA	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation rewiring degron network	0.0556
p.P1052S	TCGA-EE-A29L	SKCM	TCGA	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.2778
p.P1052S	TCGA-EE-A29L	SKCM	TCGA	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.1111
p.E409G	TCGA-HC-A6AO	PRAD	TCGA	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1111
p.E409G	DO49825	PRAD	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1111
p.D715N	DO219643	BRCA	ICGC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation blocking phosphorylation signal	0.5556
p.P1109A	DO229010	COCA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109A	DO229010	COCA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1109A	DO229013	COCA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109A	DO229013	COCA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1109A	DO229016	COCA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109A	DO229016	COCA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1109A	DO229003	COCA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109A	DO229003	COCA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.P1109A	DO229005	COCA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.P1109A	DO229005	COCA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.2222
p.C1105Y	DO233189	GACA	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.25
p.C1105Y	DO233189	GACA	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.1111
p.C1105Y	SIDM01608	Endometrial Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.25
p.C1105Y	SIDM01608	Endometrial Carcinoma	GDSC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.1111
p.C1105Y	ACH-000990	Endometrial/Uterine Cancer	CCLE	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.25
p.C1105Y	ACH-000990	Endometrial/Uterine Cancer	CCLE	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.1111
p.R397C	DO233105	GACA	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.8301
p.S360I	DO229029	LICA	ICGC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.1944
p.M388I	DO229027	LICA	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1667
p.R1103G	DO45129	LIRI	ICGC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.3056
p.R1103G	DO45129	LIRI	ICGC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.0556
p.M408I	DO24547	LUAD	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1389
p.M408K	DO24547	LUAD	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1389
p.S391Y	DO31250	OV	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.25
p.P353L	DO46996	RECA	ICGC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation altering degron motif	0.7582
p.V386A	DO42105	UCEC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1111
p.L706I	DO41020	UCEC	ICGC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation altering degron motif	0.7174
p.E402D	DO43907	UCEC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.3056
p.N406D	DO41211	UCEC	ICGC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation blocking phosphorylation signal	0.6389
p.V351I	SIDM00582	Pancreatic Carcinoma	GDSC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation altering degron motif	0.7076
p.V351I	KP-2	pancreas	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation altering degron motif	0.7076
p.G1088D	SIDM00450	Acute Myeloid Leukemia	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00351	Oral Cavity Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00585	Hepatocellular Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00024	Non-Cancerous	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00488	Colorectal Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00549	B-Lymphoblastic Leukemia	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00618	Hepatocellular Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM01449	Pancreatic Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM01617	Endometrial Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM00164	Biliary Tract Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM01694	B-Lymphoblastic Leukemia	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.G1088D	SIDM01443	Gastric Carcinoma	GDSC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.E392D	SIDM00614	Hepatocellular Carcinoma	GDSC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2778
p.E392D	ACH-000848	Liver Cancer	CCLE	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2778
p.E392D	JHH-7	liver	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2778
p.Y717H	SIDM00680	Colorectal Carcinoma	GDSC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.0556
p.Y717H	LS-180	large intestine	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.0556
p.K1059N	SIDM00602	Gastric Carcinoma	GDSC	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.0833
p.K1059N	SIDM00602	Gastric Carcinoma	GDSC	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.3056
p.K1059N	ACH-000919	Gastric Cancer	CCLE	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.0833
p.K1059N	ACH-000919	Gastric Cancer	CCLE	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.3056
p.K1059N	IM-95	stomach	COSMIC	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.0833
p.K1059N	IM-95	stomach	COSMIC	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.3056
p.Y700C	SIDM01164	Glioma	GDSC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.Y700C	ACH-000883	Brain Cancer	CCLE	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.Y700C	SW1783	central nervous system	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.N1054K	SIDM00674	Non-Cancerous	GDSC	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.2222
p.N1054K	SIDM00674	Non-Cancerous	GDSC	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.1667
p.N1054K	SIDM00675	Breast Carcinoma	GDSC	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.2222
p.N1054K	SIDM00675	Breast Carcinoma	GDSC	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.1667
p.N1054K	SIDM01009	Neuroblastoma	GDSC	PQPTPPCS	DEG_SCF_FBW7_1	1043:1050	Mutation rewiring degron network	0.2222
p.N1054K	SIDM01009	Neuroblastoma	GDSC	LVKTPDSS	DEG_SCF_FBW7_1	1060:1067	Mutation rewiring degron network	0.1667
p.D385G	SIDM00537	Colorectal Carcinoma	GDSC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.0833
p.D385G	ACH-000982	Colon/Colorectal Cancer	CCLE	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.0833
p.D385G	ACH-001345	Colon/Colorectal Cancer	CCLE	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.0833
p.D385G	GP5d	large intestine	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.0833
p.D694V	SIDM00537	Colorectal Carcinoma	GDSC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.1111
p.D694V	ACH-000982	Colon/Colorectal Cancer	CCLE	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.1111
p.D694V	ACH-001345	Colon/Colorectal Cancer	CCLE	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.1111
p.D694V	GP5d	large intestine	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.1111
p.A1042V	SIDM01059	Melanoma	GDSC	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.6936
p.A1042V	ACH-000915	Skin Cancer	CCLE	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.6936
p.A1042V	IPC-298	skin	COSMIC	VCTPLPT	DEG_SCF_FBW7_1	1036:1042	Mutation altering degron motif	0.6936
p.L398F	NCI-H1770	lung	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.6981
p.M1104T	NB1	autonomic ganglia	COSMIC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.2778
p.M1104T	NB1	autonomic ganglia	COSMIC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.0833
p.M703V	L-428	haematopoietic and lymphoid tissue	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation altering degron motif	0.7208
p.M703V	OACM5-1	oesophagus	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation altering degron motif	0.7208
p.D352A	SISO	cervix	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation altering degron motif	0.7793
p.L357F	NCI-H1770	lung	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.2778
p.D401Y	SU-DHL-1	haematopoietic and lymphoid tissue	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation altering degron motif	0.7325
p.E403K	NCI-H187	lung	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.2778
p.E404Q	HT-1376	urinary tract	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.25
p.L348F	COLO-741	large intestine	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.25
p.M1113T	NB1	autonomic ganglia	COSMIC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.7423
p.P1088S	KYSE-50	oesophagus	COSMIC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1389
p.L363F	COLO-741	large intestine	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.1111
p.V409A	SNU-1040	large intestine	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation rewiring degron network	0.1111
p.P1116S	C3A	liver	COSMIC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation altering degron motif	0.6752
p.M717T	HCT-15	large intestine	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.0556
p.P1120S	KYSE-50	oesophagus	COSMIC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.3056
p.P1107S	C3A	liver	COSMIC	LVNTPTVT	DEG_SCF_FBW7_1	1095:1102	Mutation rewiring degron network	0.1944
p.P1107S	C3A	liver	COSMIC	VFTPTLS	DEG_SCF_FBW7_1	1113:1119	Mutation rewiring degron network	0.1667
p.D393A	SISO	cervix	COSMIC	IGWTPEKT	DEG_SCF_FBW7_1	394:401	Mutation blocking ubiquitination signal	0.75
p.K344R	NCI-H810	lung	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation substituting flanking lysine	0.25
p.K359R	NCI-H810	lung	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.2222
p.R700Q	HCC2998	large intestine	COSMIC	VLPHGD	LIG_APCC_ABBA_1	702:707	Mutation rewiring degron network	0.2778
p.E363Q	HT-1376	urinary tract	COSMIC	EKENM	DEG_APCC_KENBOX_2	351:355	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KIAA0586

UniProt ID: Q9BVV6

Entrez ID: 9786

Protein name: Protein TALPID3

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KIAA0586 in