| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3SSD4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000079455 |
| Ensembl nucleotide ID | ENSPTRG00000009939 |
| Gene name | Cadherin 2 |
| Gene symbol | CDH2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Cadherins are calcium-dependent cell adhesion proteins. |
| Sequence | KAGAPEDPVS RKYEKKGKFS NCNGKRKVQY ESSEPADFKV DEDGMVYAVR SFPLSSEHAK 60 FLIYAQDKET QEKWQVAVKL SLKPTLTEES VKESAEVEEI VFPRQFSKHS GHLQRQKRDW 120 VIPPINLPEN SRGPFPQELV RIRSDRDKNL SLRYSVTGPG ADQPPTGIFI INPISGQLSV 180 TKPLDREQIA RFHLRAHAVD INGNQVENPI DIVINVIDMN DNRPEFLHQV WNGTVPEGSK 240 PGTYVMTVTA IDADDPNALN GMLRYRIVSQ APSTPSPNMF TINNETGDII TVAAGLDREK 300 VQQYTLIIQA TDMEGNPTYG LSNTATAIIT VTDVNDNPPE FTAMTFYGEV PENRVDIIVA 360 NLTVTDKDQP HTPAWNAVYR ISGGDPTGRF AIQTDPNSND GLVTVVKPID FETNRMFVLT 420 VAAENQVPLA KGIQHPPQST ATVSVTVIDV NENPYFTPNP KIIRQEEGLH AGTMLTTFTA 480 QDPDRYMQQN IRYTKLSDPA NWLKIDPVNG QITTIAVLDR ESPNVKNNIY NATFLASDNG 540 IPPMSGTGTL QIYLLDINDN APQVLPQEAE TCETPDPNSI NITALDYDID PNAGPFAFDL 600 PLSPVTIKRN WTITRLNGDF AQLNLKIKFL EAGIYEVPII ITDSGNPPKS NISILRVKVC 660 QCDSNGDCTD VDRIVGAGLG TGAIIAILLC IIILLILVLM FVVWMKRRDK ERQAKQLLID 720 PEDDVRDNIL KYDEEGGGEE DQDYDLSQLQ QPDTVEPDAI KPVGIRRMDE RPIHAEPQYP 780 VRSAAPHPGD IGDFINEGLK AADNDPTAPP YDSLLVFDYE GSGSTAGSLS SLNSSSSGGE 840 QDYDYLNDWG PRFKKLADMY GGGDD 865 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CDH2 | P19534 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 480169 | A0A5F4CJ70 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CDH2 | A0A452F6F0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 1000 | P19022 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Cdh2 | D3YYT0 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | A0A2I3SSD4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | F1SAM3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cdh2 | G3V803 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | cdh2 | G1K2E7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005509 | calcium ion binding |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO:0009966 | regulation of signal transduction |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00232 | CADHERIN_1 |