| Tag | Content |
|---|---|
| Uniprot ID | A0A5F4CJ70 |
| Entrez ID | 480169 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001287156.1 |
| Ensembl protein ID | ENSCAFP00000054452 |
| Ensembl nucleotide ID | ENSCAFG00000018115 |
| Gene name | Uncharacterized protein |
| Gene symbol | CDH2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Cadherins are calcium-dependent cell adhesion proteins. |
| Sequence | MCRIVGAPRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLSQDVH EGQPLLNVKF 60 SNCNGKRKVQ YESSEPADFK VDEDGMVYAV RSFPLSSEHA KFLIYAQDKE TQEKWQVAVK 120 LSLKPTLPED SVKESPEIEE IVFPRQATKH NGHLQRQKRD WVIPPINLPE NSRGPFPQEL 180 VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDRELI ARFHLRAHAV 240 DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGTVPEGS KPGTYVMTVT AIDADDPNAL 300 NGMLRYRILS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY 360 GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDVIV ANLTVTDKDQ PHTPAWNAAY 420 RISGGDPTGR FAIQTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 480 TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTFT AQDPDRYMQQ NIRYTKLSDP 540 ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 600 NAPQVLPQEA ETCETPDPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTITRLNGD 660 FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 720 GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 780 EDQDYDLSQL QQPDTVEPDA IKPVGIRRLD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 840 KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG EQDYDYLNDW GPRFKKLADM 900 YGGGDD 906 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CDH2 | P19534 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 480169 | A0A5F4CJ70 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CDH2 | A0A452F6F0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 1000 | P19022 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Cdh2 | D3YYT0 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | A0A2I3SSD4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | F1SAM3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cdh2 | G3V803 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | cdh2 | G1K2E7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005509 | calcium ion binding |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO:0009966 | regulation of signal transduction |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00232 | CADHERIN_1 |