| Tag | Content |
|---|---|
| Uniprot ID | G1K2E7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000003949 |
| Ensembl nucleotide ID | ENSDARG00000018693 |
| Gene name | Cadherin-2 |
| Gene symbol | cdh2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Cadherins are calcium-dependent cell adhesion proteins. |
| Sequence | MYRSGGVMLG LLAALQVAVQ GTGAMPCQPG FTENEYNVMT ADVITEGQVL LKVDFVDCGR 60 GSGLRFESGD PADFRIDADG TVMAARTLQL TDRKGQSLEI KAKDENSQEQ WMVHINFTQP 120 KQVPVILFPR HSVLVKGDDS VNRVKRDWVI PPVNVLENSR KQFPEELVKI QSDKDKSNTL 180 RYSVTGPGAD QNPTGLFIID PISGLLSVTK PLDREHIPNF HLRAHAVDIN GNQMENPIDI 240 IINVIDMNDN RPEFTHQIWN GTVDEGAKPG TFVMTVTSQD KDDPNTANGM LRYKILSQTP 300 ESPSSNMFTI NNKTGKIITV AAGLDREKVP QYTLIIQATD MEGNPTYGLS NTATAVIRLL 360 DVNDNAPEFT RETFHGEVPE NRVNVIVTNL TVTDKDEPGT PAWNAVYRII SGDPTGRFSI 420 PTDPVTNEGL VTVVKPVDFE MNRSFMLTVV ADNEVPLASG IHRTRQSTAT VSIRVIDVNE 480 SPNFDPNPKQ IKLEEGLPQW SMLTTFTAHD PDRYMQQTIS YSKLYDPANW LEIDPNNGRI 540 STIAVLDRES PYVKNNLYNA TFMASDNGVP RASGTGTLQI YLLDINDNAP RVFPQEAEVC 600 ERPEPNAINI TAVDGDLNPN AGPYAFELPN RPSDIRRNWT LTRISGDHAQ LSLKISYLES 660 GIYELPISIT DSGNLPMSNT TYLRIKVCQC DHHGDCVDME RIMAAGLGTG AIIAILICII 720 ILLVLVLMFV MWMKRRDKER QAKQLLIDPE DDVRDNILKY DEEGGGEEDQ DYDLSQLQQP 780 DTLEPDMIKP VGIRRLDERP MHSEPNYPIR SAAPHPGDIG EFIHEGLKAA DTDPTAPPYD 840 SLLVFDYEGS GSTAGSLSSL HSSSSGGDQD YDYLNDWGPR FRKLADMYGG NDD 893 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CDH2 | P19534 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 480169 | A0A5F4CJ70 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CDH2 | A0A452F6F0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | 1000 | P19022 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Cdh2 | D3YYT0 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | A0A2I3SSD4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CDH2 | F1SAM3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cdh2 | G3V803 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | cdh2 | G1K2E7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005509 | calcium ion binding |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO:0009966 | regulation of signal transduction |