| Tag | Content |
|---|---|
| Uniprot ID | A0A452G077 |
| Entrez ID | 102191048 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018053225.1 |
| Ensembl protein ID | ENSCHIP00000030116 |
| Ensembl nucleotide ID | ENSCHIG00000024990 |
| Gene name | Uncharacterized protein |
| Gene symbol | CCN2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSATGLSPVR CAFVLLLALC SRPASGQDCS APCQCPAGPV PRCPAGVSLV LDGCGCCRVC 60 AKQLSELCTE RDPCDRHKGL FCDFGSPANR KIGVCTAKDG APCVFGGTVY RSGESFQSSC 120 KYQCTCLDGS VGCVPLCSVD IRLPSPDCPF PRRVKLPGKC CEEWVCDEPK EHTVVGPALA 180 AYRPEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNAFCRL EKQSRLCMVR 240 PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT 300 LPVEFKCPDG EVMKKSMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA 349 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CCN2 | 281103 | O18739 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 476202 | J9NTX8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 102191048 | A0A452G077 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 1490 | P29279 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ccn2 | 14219 | P29268 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | CCN2 | H2QTR1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CCN2 | F1S3P6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ccn2 | 64032 | Q9R1E9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ccn2a | 321449 | Q5RI33 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0008201 | heparin binding |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005178 | integrin binding |
| GO:0008022 | protein C-terminus binding |
| GO:0001525 | angiogenesis |
| GO:0001502 | cartilage condensation |
| GO:0030154 | cell differentiation |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0035988 | chondrocyte proliferation |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0030324 | lung development |
| GO:0010629 | negative regulation of gene expression |
| GO:0001503 | ossification |
| GO:0045597 | positive regulation of cell differentiation |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| GO:0046330 | positive regulation of JNK cascade |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0072593 | reactive oxygen species metabolic process |
| GO:0032330 | regulation of chondrocyte differentiation |
| GO:0001894 | tissue homeostasis |