Gene: CCN2

Basic information

Tag Content
Uniprot ID F1S3P6
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000004525
Ensembl nucleotide ID ENSSSCG00000004192
Gene name CCN family member 2
Gene symbol CCN2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSATGLSPVR CAFVLLLALC SRPASGQDCS GQCQCAAGKA PRCPAGVSLV LDGCGCCRVC 60
AKQLGELCTE RDPCDPHKGL FCDFGSPANR KIGVCTAKDG APCVFGGTVY RSGESFQSSC 120
KYQCTCLDGA VGCVPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DHTVVGPALA 180
AYRLEDTFGP DPTMMRANCL VQTTEWSACS KTCGMGISTR VTNDNAFCRL EKQSRLCMVR 240
PCEADLEENI KKGKKCIRTP KISKPVKFEL SGCTSVKTYR AKFCGVCTDG RCCTPHRTTT 300
LPVEFKCPDG EVMKKSMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA 349

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCCN2281103O18739Bos taurusPredictionMore>>
1:1 orthologCCN2476202J9NTX8Canis lupus familiarisPredictionMore>>
1:1 orthologCCN2102191048A0A452G077Capra hircusPredictionMore>>
1:1 orthologCCN21490P29279Homo sapiensPredictionMore>>
1:1 orthologCcn214219P29268CPOMus musculusPublicationMore>>
1:1 orthologCCN2H2QTR1Pan troglodytesPredictionMore>>
1:1 orthologCCN2F1S3P6Sus scrofaPredictionMore>>
1:1 orthologCcn264032Q9R1E9Rattus norvegicusPredictionMore>>
1:1 orthologccn2a321449Q5RI33Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005520 insulin-like growth factor binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR006207 Cys_knot_C
IPR006208 Glyco_hormone_CN
IPR009030 Growth_fac_rcpt_cys_sf
IPR000867 IGFBP-like
IPR012395 IGFBP_CNN
IPR017891 Insulin_GF-bd_Cys-rich_CS
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
IPR001007 VWF_dom

PROSITE

PROSITE ID PROSITE Term
PS01185 CTCK_1
PS01225 CTCK_2
PS00222 IGFBP_N_1
PS51323 IGFBP_N_2
PS50092 TSP1
PS01208 VWFC_1
PS50184 VWFC_2

Pfam

Pfam ID Pfam Term
PF00007 Cys_knot
PF00219 IGFBP
PF00090 TSP_1
PF00093 VWC