| Tag | Content |
|---|---|
| Uniprot ID | J9NTX8 |
| Entrez ID | 476202 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003638769.3 |
| Ensembl protein ID | ENSCAFP00000036615 |
| Ensembl nucleotide ID | ENSCAFG00000029442 |
| Gene name | Cellular communication network factor 2 |
| Gene symbol | CCN2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSAAGLGPVR GAFLLLLALC GRPAAGQDCG GQCPCAAAPA PRCPAGVSLV LDGCGCCRVC 60 AKQLGELCTE RDPCDPHKGL FCDFGSPANR KIGVCTAKDG APCVFGGTVY RSGESFQSSC 120 KYQCTCLDGA VGCVPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DHTVVGPALA 180 AYRLEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNAFCRL EKQSRLCMVR 240 PCEADLEENI KKGKKCIRTP KIAKPVKFEL SGCTSVKTYR AKFCGVCTDG RCCTPHRTTT 300 LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA 349 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CCN2 | 281103 | O18739 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 476202 | J9NTX8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 102191048 | A0A452G077 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 1490 | P29279 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ccn2 | 14219 | P29268 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | CCN2 | H2QTR1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CCN2 | F1S3P6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ccn2 | 64032 | Q9R1E9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ccn2a | 321449 | Q5RI33 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0008201 | heparin binding |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005178 | integrin binding |
| GO:0008022 | protein C-terminus binding |
| GO:0007155 | cell adhesion |
| GO:0060548 | negative regulation of cell death |
| GO:0045597 | positive regulation of cell differentiation |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| GO:0046330 | positive regulation of JNK cascade |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0007165 | signal transduction |