| Tag | Content |
|---|---|
| Uniprot ID | H2QTR1; A0A2J8PT76; |
| Entrez ID | |
| Genbank protein ID | JAA41690.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000090133 |
| Ensembl nucleotide ID | ENSPTRG00000046307 |
| Gene name | Cellular communication network factor 2 |
| Gene symbol | CCN2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTAASVGPVR VAFVLLLALC SRPAVGQNCS GPCRCSDEPA PRCPAGVSLV LDGCGCCRVC 60 AKQLGELCTE RDPCDPHKGL FCDFGSPANR KIGVCTAKDG APCIFGGTVY RSGESFQSSC 120 KYQCTCLDGA VGCMPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DQTVVGPALA 180 AYRLEDTFGP DPTMMRANCL VQTTEWSACS KTCGMGISTR VTNDNASCRL EKQSRLCMVR 240 PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT 300 LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA 349 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CCN2 | 281103 | O18739 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 476202 | J9NTX8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 102191048 | A0A452G077 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CCN2 | 1490 | P29279 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ccn2 | 14219 | P29268 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | CCN2 | H2QTR1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CCN2 | F1S3P6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ccn2 | 64032 | Q9R1E9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ccn2a | 321449 | Q5RI33 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0008201 | heparin binding |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005178 | integrin binding |
| GO:0008022 | protein C-terminus binding |
| GO:0001525 | angiogenesis |
| GO:0001502 | cartilage condensation |
| GO:0007155 | cell adhesion |
| GO:0030154 | cell differentiation |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0035988 | chondrocyte proliferation |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0030324 | lung development |
| GO:0060548 | negative regulation of cell death |
| GO:0010629 | negative regulation of gene expression |
| GO:0001503 | ossification |
| GO:0045597 | positive regulation of cell differentiation |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| GO:0046330 | positive regulation of JNK cascade |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0072593 | reactive oxygen species metabolic process |
| GO:0032330 | regulation of chondrocyte differentiation |
| GO:0007165 | signal transduction |
| GO:0001894 | tissue homeostasis |