Gene:

Basic information

Tag Content
Uniprot ID A0A4X1TCF4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00070012892; ENSSSCP00070012899;
Ensembl nucleotide ID ENSSSCG00070007962
Gene name Integrin beta
Gene symbol
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDFISGGSRN ERCDIVSNLI NKGCSVNLIE YPSVHVIPSE NEKNTQVTPG EVLIQLREGA 60
KANFMLKIHP LKKYPVDLYY LVDVSASMHN NIEKLNTVGN DLSRKMAFFS RDFRLGFGSY 120
VDKTVSPYIS IHPERIHNQC SDYNLDCMPP HGYIHVLSLT ENITEFEKAV HRQKISGNID 180
TPEGGFDAML QAAVCESHIG WRKEAKRLLL VMTDQTSHLA LDSKLAGIVV PNDGNCHLKN 240
NVYIRSTSME HPSLGQLSEK LIDNNINVIF AVQGKQFHWY KDLLPLLPGT IAGEIESKAA 300
NLNNLVVEAY QKLISEVKVQ VENQVKGIYF NITAICPDGT RKPGTDGCRN VTSNDEVLFN 360
VTVTMEKCDV TGGKSYAIIK PIGFNETTKI HIHRNCSCQC DDSRELKRKC VEETFLDAKC 420
SQCDENKCHF DEDQFPSESC KSHKDQPVCS GRGVCICGKC LCHKIKLGKV YGKYCEKDDF 480
SCPYHHGNLC AGHGECEAGK CQCFRGWEGD RCQCPSASTQ HCVNPKGQVC SGRGTCVCGR 540
CECTDPRSIG RFCEHCPTCH TACNENWNCV QCLHPHNLSQ AILDQCKTSC ALKEQHYADQ 600
MSECFSSPSY LRIFFIIFIV TFLIGLLKVL IIRQVILQWN SNKIKSSADY RVSASKKDKS 660
ILQSVCTRAV TYRREKPEEI KMDISKLNAH ETFRCNF 697

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologITGB8536286F1MVW3Bos taurusPredictionMore>>
1:1 orthologITGB8475253F6X717Canis lupus familiarisPredictionMore>>
1:1 orthologITGB8102191301A0A452F9L9Capra hircusPredictionMore>>
1:1 orthologITGB8100053462F7BLS7Equus caballusPredictionMore>>
1:1 orthologITGB83696P26012Homo sapiensPredictionMore>>
1:1 orthologItgb8320910Q0VBD0CPOMus musculusPublicationMore>>
1:1 orthologA0A4X1TCF4Sus scrofaPredictionMore>>
1:1 orthologITGB8100009141P26013Oryctolagus cuniculusPredictionMore>>
1:1 orthologItgb8362800A0A0G2JVU1Rattus norvegicusPredictionMore>>
1:1 orthologitgb8F1QN46Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0008305 integrin complex
GO:0038023 signaling receptor activity
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0130 Cell adhesion
KW-0401 Integrin
KW-0472 Membrane
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013032 EGF-like_CS
IPR013111 EGF_extracell
IPR015812 Integrin_bsu
IPR015442 Integrin_bsu-8
IPR002369 Integrin_bsu_VWA
IPR032695 Integrin_dom_sf
IPR036465 vWFA_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS00022 EGF_1
PS00243 INTEGRIN_BETA

Pfam

Pfam ID Pfam Term
PF07974 EGF_2
PF00362 Integrin_beta