| Tag | Content |
|---|---|
| Uniprot ID | F7BLS7 |
| Entrez ID | 100053462 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001497221.4 |
| Ensembl protein ID | ENSECAP00000016855 |
| Ensembl nucleotide ID | ENSECAG00000019215 |
| Gene name | Integrin beta |
| Gene symbol | ITGB8 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MCRSTLAFFT AAFVCLQNCR PGPAPFLRAA WVFSVVLGLG QSEDNRCASS NAASCTKCLA 60 LGPECGWCAQ EDFISGGSRS VRCDIVSNLI SKGCLIDSIE YPSVHVMPSE NEINTQVTPG 120 EVSIQLRPGA KANFMLKIHP LKQYPVDLYY LVDVSASMHN NIEKLNSVGN DLSRKMAFFS 180 RDFRLGFGSY VDKTVSPYIS IHPERIHNQC SDYNLDCMPP HGYIHVLSLT ENITEFEKAV 240 HRQKISGNID TPEGGFDAML QAAVCESHIG WRKEAKRLLL VMTDQTSHLA LDSKLAGIVV 300 PNDGNCHLKN NVYVRSTSME HPSLGQLSEK LIDNNINVIF AVQGKQFHWY KDLLPLLPGT 360 IAGEIESKAA NLNNLVVEAY QKLISEVKVQ VENQAKGIYF NITAICPDGT RKPGTDGCGN 420 VTSNDEVLFN VTVTMKKCDV TEGKSYAIIK PIGFNETTKI HIHRNCSCQC DDSRGSKRKC 480 VDETFLDAKC FQCDENKCHF DEDQFPSESC KSHKDQPVCS GRGVCICGKC LCHKIKLGKV 540 YGKYCEKDDF SCPYHQGNLC AGHGECEAGR CQCFSGWEGD RCQCPSASAQ HCVNPKGQVC 600 SGRGTCVCGK CECTDPKSIG RFCEHCPTCH TACNENWNCV QCLHPHNLSQ AILDRCKTSC 660 ALMEQHYVDQ TSECFSSPSY LRIFFIIFIV TFLIGLLKVL IIRQVILQWN SNKIKSSADY 720 RVSASKKDKL ILQSVCTRAV TYRREKPEEI KMDISKLNAH ETFRCNF 767 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB8 | 536286 | F1MVW3 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 475253 | F6X717 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 102191301 | A0A452F9L9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 100053462 | F7BLS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 3696 | P26012 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 320910 | Q0VBD0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | A0A4X1TCF4 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | ITGB8 | 100009141 | P26013 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 362800 | A0A0G2JVU1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | itgb8 | F1QN46 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005925 | focal adhesion |
| GO:0034686 | integrin alphav-beta8 complex |
| GO:1990430 | extracellular matrix protein binding |
| GO:0005178 | integrin binding |
| GO:0038023 | signaling receptor activity |
| GO:0051216 | cartilage development |
| GO:0033627 | cell adhesion mediated by integrin |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0001573 | ganglioside metabolic process |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0010629 | negative regulation of gene expression |
| GO:0045766 | positive regulation of angiogenesis |
| GO:0010628 | positive regulation of gene expression |
| GO:1901388 | regulation of transforming growth factor beta activation |
| GO:0001570 | vasculogenesis |