| Tag | Content |
|---|---|
| Uniprot ID | F6X717 |
| Entrez ID | 475253 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005628606.1 |
| Ensembl protein ID | ENSCAFP00000003676 |
| Ensembl nucleotide ID | ENSCAFG00000002519 |
| Gene name | Integrin beta |
| Gene symbol | ITGB8 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MCRSALAFFA AAFVRLQNCR PGPAPFLRAA WVLLVVLGLG QSEDNRCTSS NAASCTKCLA 60 LGPECGWCAQ EDFISGGLRS ERCDIISNLI SKGCSTDSIE YPSVHVIPSE NEINTQVTPG 120 EVLIQLRPEA EANFMLKIHP LKKYPVDLYY LVDVSASMHN NIEKLNSVGN DLSRKMAYFS 180 RDFRLGFGSY VDKTVSPYIS IHPERIHNQC SDYNLDCMPP HGYIHVLSLT ENITEFEKAV 240 HRQKISGNID TPEGGFDAML QAAVCESHIG WRKEAKRLLL VMTDQTSHLA LDSKLAGIVV 300 PNDGNCHLKN NIYVRSTSME HPSLGQLSEK LIDNNINVIF AVQGKQFHWY KDLLPLLPGT 360 IAGEIESKAA NLNNLVIDAY QKLISEVKVQ VENQVKGVYF NITAICPDGT RKPGTDGCGN 420 VTSNDEVLFN VTVTMKKCDV TGGKSYAIIK PIGFNETTKI HIHRNCSCQC DDGRGSKRKC 480 VDEIFLDAKC FQCNENKCHF DEAQFPSETC KSHKDQPVCS GRGVCVCGKC LCHKVKFGKV 540 YGKYCEKDDF SCPYHHGNLC AGHGECEAGR CQCFSGWEGD RCQCPSASAQ HCVNPKGQVC 600 SGRGTCVCGR CECTDPGSIG RFCEHCPTCH TACSENWNCV QCLRPHNLSQ AILDRCKTSC 660 ALMEQHYMEQ TSECFSSPSY LRIFFIIFIV TFLIGLLKVL IIRQVILQWN SNKIKSSADY 720 RVSASKKDKL ILQSVCTRAV TYRREKPEEI KMDISKLNAH ETFRRRQTVL DHAGCWLST 779 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB8 | 536286 | F1MVW3 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 475253 | F6X717 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 102191301 | A0A452F9L9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 100053462 | F7BLS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 3696 | P26012 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 320910 | Q0VBD0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | A0A4X1TCF4 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | ITGB8 | 100009141 | P26013 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 362800 | A0A0G2JVU1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | itgb8 | F1QN46 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005925 | focal adhesion |
| GO:0008305 | integrin complex |
| GO:0005178 | integrin binding |
| GO:0038023 | signaling receptor activity |
| GO:0033627 | cell adhesion mediated by integrin |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0007229 | integrin-mediated signaling pathway |