| Tag | Content |
|---|---|
| Uniprot ID | F1QN46 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000117882 |
| Ensembl nucleotide ID | ENSDARG00000028222 |
| Gene name | Integrin beta |
| Gene symbol | itgb8 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQDNLDRLKT VGLALSHQMK QHSSDFRVGF GSFVDKPVSP YIDVHPSKLL NPCSEYEVHC 60 RPAHGFIHVL PVTQNMSEFT RVIQEQRISG NMDTPEGGFD AMLQATVCQK DIGWRPEAKH 120 LLLVMTDQPS HLALDSKLAG IVVPHDGRCH LEDNVYSQTS TMEHPTVAQL AEKLLENSIY 180 SIFAVDHLQY QWYEDLVDLI PGSYVGRLFP KASNLKDLVV QAYKKLLSDV EVQMELQDPQ 240 QAERFWVNVS AICPGGSSAA GNSKCSGVQP KQTVFFQLTV GMLSCPAGSA DQDVLMLVRP 300 VGFNESVRVR IRQLCGSGCT DPKPEPSSCT TNASDSCREH RNTPVCSSRG VCRCGTCVCD 360 SSRFGNIYGK FCEMDDFSCP YDGGLVCGGH GRCVRGECVC FSGWTGEACA CRESTDSCVS 420 DDGFICGDRG RCVCGKCVCD DPRRSGAFCE KCPMCHSSCQ SHWNCVNCHL SNGLGSDGFQ 480 LCNQSCSPLV DYVDDITELV RGKYCLYPST DKCQYRFLME LASDGAQLHI SRHPVCVWSR 540 RYFKTFLSVF LLTVTLGIGM LAGVRQLLRV TGRSCISKTE PQFEHTHKDS SYVPTSSEKT 600 ITYRRDRLPN HPVEMHTHTP TLTHKMPIGD AW 632 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB8 | 536286 | F1MVW3 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 475253 | F6X717 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 102191301 | A0A452F9L9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 100053462 | F7BLS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ITGB8 | 3696 | P26012 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 320910 | Q0VBD0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | A0A4X1TCF4 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | ITGB8 | 100009141 | P26013 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb8 | 362800 | A0A0G2JVU1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | itgb8 | F1QN46 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005925 | focal adhesion |
| GO:0008305 | integrin complex |
| GO:0005178 | integrin binding |
| GO:0038023 | signaling receptor activity |
| GO:0001525 | angiogenesis |
| GO:0001568 | blood vessel development |
| GO:0033627 | cell adhesion mediated by integrin |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0001935 | endothelial cell proliferation |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0001944 | vasculature development |