Gene Page: FARSB

Summary
GeneID  10056
Symbol  FARSB
Synonyms  FARSLB|FRSB|HSPC173|PheHB|PheRS
Description  phenylalanyl-tRNA synthetase, beta subunit
See related  HGNC:17800|MIM:609690|Ensembl:ENSG00000116120|HPRD:09947|
Locus tag  -
Gene type  protein-coding
Map location  2q36.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FIBCD10.580.39
C2orf850.570.28
CNGB10.560.49
SUSD40.560.54
AQP30.550.28
PRKCG0.530.51
CARTPT0.520.46
DRD50.510.45
DNAJC120.510.49
GABRQ0.510.42
Top 10 negatively co-expressed genes
SMTN-0.29-0.36
AL953897.2-0.28-0.21
C1orf187-0.26-0.15
AC005035.1-0.26-0.31
NEO1-0.25-0.24
KIAA1949-0.25-0.21
EDARADD-0.25-0.26
RBMX2-0.25-0.30
SLC44A5-0.25-0.13
LPL-0.25-0.22
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004826phenylalanine-tRNA ligase activityTAS10049785 
GO:0016874ligase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006432phenylalanyl-tRNA aminoacylationIEA-
GO:0006412translationTAS10049785 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005625soluble fractionTAS10049785 
GO:0005737cytoplasmTAS10049785 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 4133All SZGR genes in this pathway
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 2419All SZGR genes in this pathway
REACTOME_TRNA_AMINOACYLATION 4234All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
ZHANG_RESPONSE_TO_CANTHARIDIN_DN 6946All SZGR genes in this pathway
TSENG_IRS1_TARGETS_UP 11371All SZGR genes in this pathway
BILD_MYC_ONCOGENIC_SIGNATURE 206117All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
SANSOM_APC_TARGETS_REQUIRE_MYC 210123All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA 5135All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN 13899All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 10368All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway


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