Gene Page: MPHOSPH6

Summary
GeneID  10200
Symbol  MPHOSPH6
Synonyms  MPP|MPP-6|MPP6
Description  M-phase phosphoprotein 6
See related  HGNC:7214|MIM:605500|Ensembl:ENSG00000135698|HPRD:16111|
Locus tag  -
Gene type  protein-coding
Map location  16q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.3604 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MAP4K20.780.79
FAM73B0.770.73
XYLT20.760.81
SPOCK20.750.69
PLBD20.740.67
ESYT30.740.67
DGKQ0.740.71
SLC6A70.730.66
ABCG40.730.62
GALNT90.730.65
Top 10 negatively co-expressed genes
C9orf46-0.41-0.49
RPL31-0.39-0.48
AC008073.1-0.39-0.42
RPS6-0.39-0.51
FAM36A-0.38-0.41
FABP7-0.38-0.55
RPS3AP47-0.38-0.46
IFI44-0.38-0.46
TPT1-0.38-0.47
RPS20-0.37-0.55
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15231747 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000087M phase of mitotic cell cycleTAS8885239 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AATFCHE-1 | CHE1 | DEDapoptosis antagonizing transcription factor-HPRD15231747 
APLP1APLPamyloid beta (A4) precursor-like protein 1Two-hybridBioGRID16169070 
ARHGAP18FLJ25728 | MGC126757 | MGC138145 | MacGAP | bA307O14.2Rho GTPase activating protein 18-HPRD15231747 
C14orf1ERG28 | NET51chromosome 14 open reading frame 1Two-hybridBioGRID16169070 
C1orf103FLJ11269 | RIF1 | RP11-96K19.1chromosome 1 open reading frame 103Two-hybridBioGRID16169070 
C7orf64DKFZP564O0523 | DKFZp686D1651 | HSPC304chromosome 7 open reading frame 64Two-hybridBioGRID16169070 
DNM2CMTDI1 | CMTDIB | DI-CMTB | DYN2 | DYNIIdynamin 2-HPRD15231747 
DYNLRB1BITH | BLP | DNCL2A | DNLC2A | ROBLD1dynein, light chain, roadblock-type 1-HPRD15231747 
EIF3GEIF3-P42 | EIF3S4 | eIF3-delta | eIF3-p44eukaryotic translation initiation factor 3, subunit G-HPRD15231747 
EXOSC10PM-Scl | PM/Scl-100 | PMSCL | PMSCL2 | RRP6 | Rrp6p | p2 | p3 | p4exosome component 10-HPRD15231747 
GDF9-growth differentiation factor 9Two-hybridBioGRID16169070 
PARNDANpoly(A)-specific ribonuclease (deadenylation nuclease)-HPRD15231747 
RPS20FLJ27451 | MGC102930ribosomal protein S20-HPRD15231747 
SKIV2L2Dob1 | KIAA0052 | MGC142069 | Mtr4 | fSAP118superkiller viralicidic activity 2-like 2 (S. cerevisiae)-HPRD15231747 
SMARCA4BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2bSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4-HPRD15231747 
SNX9MST155 | MSTP155 | SDP1 | SH3PX1 | SH3PXD3A | WISPsorting nexin 9-HPRD15231747 
THOP1EP24.15 | MEPD_HUMAN | MP78 | TOPthimet oligopeptidase 1-HPRD15231747 
TLE1ESG | ESG1 | GRG1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)Two-hybridBioGRID16169070 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53Two-hybridBioGRID16169070 
UNC119HRG4unc-119 homolog (C. elegans)Two-hybridBioGRID16169070 
ZHX1-zinc fingers and homeoboxes 1Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DOANE_BREAST_CANCER_CLASSES_UP 7238All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN 12686All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_DN 162116All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP 194112All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN 234147All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN 8454All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
JIANG_VHL_TARGETS 13891All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D5 3926All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
SMID_BREAST_CANCER_ERBB2_UP 14783All SZGR genes in this pathway
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP 8363All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_UP 12778All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP 11573All SZGR genes in this pathway


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