Gene Page: FARS2

Summary
GeneID  10667
Symbol  FARS2
Synonyms  FARS1|HSPC320|PheRS|dJ520B18.2
Description  phenylalanyl-tRNA synthetase 2, mitochondrial
See related  HGNC:21062|MIM:611592|Ensembl:ENSG00000145982|HPRD:09946|
Locus tag  RP1-236A3.1
Gene type  protein-coding
Map location  6p25.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PIP5K2B0.890.91
AP003115.10.880.91
NOLC10.880.89
PUM10.880.89
SLC35E10.870.89
TRIM320.870.88
RNF1110.870.89
AP1G10.870.89
POLR3A0.870.90
DCTN50.870.88
Top 10 negatively co-expressed genes
AF347015.31-0.77-0.83
MT-CO2-0.76-0.82
HIGD1B-0.75-0.82
FXYD1-0.74-0.80
MT-CYB-0.73-0.79
AF347015.33-0.72-0.77
IFI27-0.72-0.77
AF347015.21-0.71-0.83
AC021016.1-0.71-0.77
CST3-0.71-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000049tRNA bindingIDA10329163 
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004826phenylalanine-tRNA ligase activityIDA10329163 
GO:0004826phenylalanine-tRNA ligase activityIEA-
GO:0016874ligase activityIEA-
GO:0005215transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006432phenylalanyl-tRNA aminoacylationIDA10329163 
GO:0006432phenylalanyl-tRNA aminoacylationIEA-
GO:0006412translationIEA-
GO:0008033tRNA processingIDA10329163 
GO:0006810transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005625soluble fractionIDA10329163 
GO:0005737cytoplasmIEA-
GO:0005739mitochondrionIEA-
GO:0005759mitochondrial matrixIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 4133All SZGR genes in this pathway
REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 2117All SZGR genes in this pathway
REACTOME_TRNA_AMINOACYLATION 4234All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP 6045All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
AFFAR_YY1_TARGETS_DN 234137All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
GAJATE_RESPONSE_TO_TRABECTEDIN_DN 1911All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_UP 7353All SZGR genes in this pathway
AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 10963All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 7954All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_DN 6136All SZGR genes in this pathway


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