Summary ?
Descriptionchromogranin B
Gene typeprotein-coding
Map location20p12.3
Pascal p-value0.558
Sherlock p-value0.47
Fetal beta-1.661
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
AssociationA combined odds ratio method (Sun et al. 2008), association studies3Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS3608978 
GO:0005515protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-

Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACACAACAC | ACC | ACC1 | ACCAacetyl-Coenzyme A carboxylase alphaTwo-hybridBioGRID16169070 
ATXN2ATX2 | FLJ46772 | SCA2 | TNRC13ataxin 2Two-hybridBioGRID16169070 
CBFBPEBP2Bcore-binding factor, beta subunitTwo-hybridBioGRID16169070 
CCDC92FLJ22471coiled-coil domain containing 92Two-hybridBioGRID16169070 
FGFR3ACH | CD333 | CEK2 | HSFGFR3EX | JTK4fibroblast growth factor receptor 3Two-hybridBioGRID16169070 
GCS1-glucosidase ITwo-hybridBioGRID16169070 
MARK3CTAK1 | KP78 | PAR1AMAP/microtubule affinity-regulating kinase 3Two-hybridBioGRID16169070 
MGLLHU-K5 | MGLmonoglyceride lipaseTwo-hybridBioGRID16169070 
OGG1HMMH | HOGG1 | MUTM | OGH18-oxoguanine DNA glycosylaseTwo-hybridBioGRID16169070 
POLD1CDC2 | POLDpolymerase (DNA directed), delta 1, catalytic subunit 125kDaTwo-hybridBioGRID16169070 
PRAGMINDKFZp761P0423homolog of rat pragma of Rnd2Two-hybridBioGRID16169070 
PTEN10q23del | BZS | MGC11227 | MHAM | MMAC1 | PTEN1 | TEP1phosphatase and tensin homologTwo-hybridBioGRID16169070 
S100A860B8AG | CAGA | CFAG | CGLA | CP-10 | L1Ag | MA387 | MIF | MRP8 | NIF | P8S100 calcium binding protein A8Two-hybridBioGRID16169070 
SAFB2KIAA0138scaffold attachment factor B2Two-hybridBioGRID16169070 
SLC25A6AAC3 | ANT3 | ANT3Y | MGC17525solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6Two-hybridBioGRID16169070 
TAZBTHS | CMD3A | EFE | EFE2 | FLJ27390 | G4.5 | LVNCX | Taz1 | XAP-2tafazzinTwo-hybridBioGRID16169070 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2ATwo-hybridBioGRID16169070 
TWF2A6RP | A6r | MSTP011 | PTK9Ltwinfilin, actin-binding protein, homolog 2 (Drosophila)Two-hybridBioGRID16169070 
YLPM1C14orf170 | ZAP | ZAP3YLP motif containing 1Two-hybridBioGRID16169070 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
VECCHI GASTRIC CANCER EARLY DN 367220All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 1 UP 276165All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 SIGNATURE 3 UP 341197All SZGR 2.0 genes in this pathway
SABATES COLORECTAL ADENOMA DN 291176All SZGR 2.0 genes in this pathway
PROVENZANI METASTASIS UP 194112All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP 238135All SZGR 2.0 genes in this pathway
KIM MYC AMPLIFICATION TARGETS UP 201127All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER F 5432All SZGR 2.0 genes in this pathway
KIM GERMINAL CENTER T HELPER UP 6642All SZGR 2.0 genes in this pathway
RORIE TARGETS OF EWSR1 FLI1 FUSION DN 3023All SZGR 2.0 genes in this pathway
LU AGING BRAIN DN 153120All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE UP 249170All SZGR 2.0 genes in this pathway
LEIN NEURON MARKERS 6945All SZGR 2.0 genes in this pathway
LEIN LOCALIZED TO PROXIMAL DENDRITES 3726All SZGR 2.0 genes in this pathway
WANG LSD1 TARGETS DN 3930All SZGR 2.0 genes in this pathway
OSADA ASCL1 TARGETS UP 4630All SZGR 2.0 genes in this pathway
BRUECKNER TARGETS OF MIRLET7A3 UP 11169All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME2 491319All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3K27ME3 590403All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR UP 548370All SZGR 2.0 genes in this pathway
ROESSLER LIVER CANCER METASTASIS UP 10772All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method