Gene Page: VPS45

Summary
GeneID  11311
Symbol  VPS45
Synonyms  H1|H1VPS45|VPS45A|VPS45B|VPS54A|VSP45|VSP45A
Description  vacuolar protein sorting 45 homolog (S. cerevisiae)
See related  HGNC:14579|MIM:610035|Ensembl:ENSG00000136631|HPRD:10301|
Locus tag  RP11-458I7.2
Gene type  protein-coding
Map location  1q21.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006954inflammatory responseTAS10404641 
GO:0006904vesicle docking during exocytosisIEA-
GO:0006886intracellular protein transportTAS10404641 
GO:0016192vesicle-mediated transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005798Golgi-associated vesicleTAS8996080 
GO:0005764lysosomeTAS8996080 
GO:0005768endosomeIEA-
GO:0016020membraneIEA-
GO:0010008endosome membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
RAB5ARAB5RAB5A, member RAS oncogene familyAffinity Capture-MSBioGRID11062261 
SNTG1G1SYN | SYN4syntrophin, gamma 1Reconstituted ComplexBioGRID11062261 
STX16MGC90328 | SYN16 | hsyn16syntaxin 16-HPRD12110575 
VPS11END1 | PEP5 | RNF108 | hVPS11vacuolar protein sorting 11 homolog (S. cerevisiae)VPS11 interacts with VPS45A (VPS45). This interaction was modeled on a demonstrated interaction between human VPS11 and rat VPS45.BIND14623309 
VPS18KIAA1475 | PEP3vacuolar protein sorting 18 homolog (S. cerevisiae)VPS18 interacts with VPS45A (VPS45). This interaction was modeled on a demonstrated interaction between human VPS18 and rat VPS45.BIND14623309 
ZFYVE20FLJ34993 | MGC126210 | Rabenosyn-5zinc finger, FYVE domain containing 20-HPRD11062261 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 132101All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
ASTIER_INTEGRIN_SIGNALING 5944All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR 14984All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C 463262All SZGR genes in this pathway
HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN 5036All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN 204114All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_UP 207143All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.