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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: EPHA7

Summary

GeneID

2045

Symbol

EPHA7

Synonyms

EHK3|HEK11

Description

EPH receptor A7

Locus tag

Gene type

protein-coding

Map location

6q16.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

NAPG

0.94

MAPK9

0.94

0.93

ATP6V1C1

0.93

B4GALT6

0.92

0.93

IDH3A

0.91

0.92

GLS

0.91

0.94

GLRB

0.91

0.92

SYT1

0.91

0.90

MOAP1

0.91

0.92

MAP2K4

0.90

0.88

Top 10 negatively co-expressed genes

BCL7C

-0.49

-0.56

EFEMP2

-0.47

-0.48

NME4

-0.45

-0.57

CLEC3B

-0.45

-0.52

AL022328.1

-0.45

-0.48

RAB34

-0.44

-0.48

AC006276.2

-0.43

IRF7

-0.42

-0.53

SIGIRR

-0.42

-0.49

AP003068.3

-0.41

-0.40

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0004872

receptor activity

IEA

GO:0005003

ephrin receptor activity

IEA

GO:0005515

protein binding

ISS

GO:0005524

ATP binding

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

IEA

GO:0006468

protein amino acid phosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EFNA2	ELF-1 \| EPLG6 \| HEK7-L \| LERK6	ephrin-A2	Affinity Capture-Western	BioGRID	10366629
EFNA3	EFL2 \| EPLG3 \| Ehk1-L \| LERK3	ephrin-A3	Affinity Capture-Western	BioGRID	10366629
EFNA5	AF1 \| EFL5 \| EPLG7 \| GLC1M \| LERK7 \| RAGS	ephrin-A5	Affinity Capture-Western	BioGRID	10366629
MLLT4	AF-6 \| AF6 \| AFADIN \| FLJ34371 \| RP3-431P23.3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	-	HPRD,BioGRID	9707552
MLLT4	AF-6 \| AF6 \| AFADIN \| FLJ34371 \| RP3-431P23.3		EphA7 interacts with AF6. This interaction was modelled on a demonstrated interaction between human EphB6 and AF6 from an unspecified species.	BIND	9707552
SDCBP	MDA-9 \| ST1 \| SYCL \| TACIP18	syndecan binding protein (syntenin)	EphA7 interacts with ST-1. This interaction was modelled on a demonstrated interaction between human EphA7 and rat ST-1.	BIND	11152476

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_AXON_GUIDANCE	129	103	All SZGR genes in this pathway
PID_EPHA_FWDPATHWAY	34	29	All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN	481	290	All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP	423	283	All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN	291	176	All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN	781	465	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP	238	135	All SZGR genes in this pathway
DAWSON_METHYLATED_IN_LYMPHOMA_TCL1	59	45	All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP	1037	673	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	514	330	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	428	306	All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION	475	313	All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP	214	133	All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_UP	36	27	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS	92	68	All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	165	118	All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN	138	92	All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP	491	316	All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE	721	492	All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN	505	328	All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	1080	713	All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_UP	169	105	All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4	110	66	All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN	244	157	All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP	54	38	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	73	79	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	73	79	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-133	1733	1739	1A	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	1733	1739	1A	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-134	1940	1946	m8	hsa-miR-134^brain	UGUGACUGGUUGACCAGAGGG
miR-137	1316	1323	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-137	1316	1323	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-141/200a	1818	1825	1A,m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	1818	1825	1A,m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-142-5p	1335	1341	1A	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-15/16/195/424/497	74	81	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-17-5p/20/93.mr/106/519.d	776	782	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-181	1352	1358	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-182	671	677	m8	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-196	237	243	m8	hsa-miR-196a	UAGGUAGUUUCAUGUUGUUGG
miR-196	237	243	m8	hsa-miR-196b	UAGGUAGUUUCCUGUUGUUGG
miR-199	508	514	m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	508	514	m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-203.1	1612	1618	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-204/211	177	184	1A,m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	177	184	1A,m8	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-26	144	150	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	144	150	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-299-3p	1723	1729	m8	hsa-miR-299-3p	UAUGUGGGAUGGUAAACCGCUU
miR-30-3p	242	248	1A	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	242	248	1A	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-378*	1031	1037	1A	hsa-miR-422b	CUGGACUUGGAGUCAGAAGGCC
miR-378*	1031	1037	1A	hsa-miR-422a	CUGGACUUAGGGUCAGAAGGCC
miR-433-3p	347	353	m8	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-433-3p	347	353	m8	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-493-5p	304	310	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-503	75	81	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-539	1614	1620	m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU
miR-9	1430	1436	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA
miR-9	1430	1436	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.