Gene Page: PHLDA1

Summary
GeneID  22822
Symbol  PHLDA1
Synonyms  DT1P1B11|MGC131738|PHRIP|TDAG51
Description  pleckstrin homology-like domain, family A, member 1
See related  HGNC:8933|MIM:605335|Ensembl:ENSG00000139289|HPRD:05625|
Locus tag  -
Gene type  protein-coding
Map location  12q15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CREBBP0.980.99
EP4000.960.97
CRAMP1L0.960.97
BAT2L0.960.97
ZCCHC140.960.97
CELSR30.960.96
DIDO10.960.96
PRR120.950.98
BCL9L0.950.96
INSR0.950.94
Top 10 negatively co-expressed genes
AF347015.31-0.68-0.86
S100B-0.68-0.83
C5orf53-0.68-0.75
SERPINB6-0.67-0.74
MT-CO2-0.66-0.85
ACOT13-0.66-0.72
FXYD1-0.66-0.82
AIFM3-0.65-0.71
B2M-0.65-0.78
AF347015.27-0.65-0.81
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI11369516 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006915apoptosisIEA-
GO:0045210FasL biosynthetic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0030659cytoplasmic vesicle membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EIF3DEIF3S7 | MGC126526 | MGC17258 | eIF3-p66 | eIF3-zetaeukaryotic translation initiation factor 3, subunit DReconstituted Complex
Two-hybrid		BioGRID11369516 
KRTAP4-12KAP4.12 | KRTAP4.12keratin associated protein 4-12Two-hybridBioGRID16189514 
MDFII-MF | I-mfaMyoD family inhibitorTwo-hybridBioGRID16189514 
PABPC4APP-1 | APP1 | FLJ43938 | PABP4 | iPABPpoly(A) binding protein, cytoplasmic 4 (inducible form)-HPRD,BioGRID11369516 
PLSCR1MMTRA1Bphospholipid scramblase 1Two-hybridBioGRID16189514 
RPL14CAG-ISL-7 | CTG-B33 | L14 | MGC88594 | RL14 | hRL14ribosomal protein L14Reconstituted Complex
Two-hybrid		BioGRID11369516 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN 2015All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN 65All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN 6849All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
PRAMOONJAGO_SOX4_TARGETS_UP 5238All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN 14591All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN 384230All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP 233161All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP 185126All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP 157104All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP 2115All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP 4430All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_UP 238144All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_UP 5534All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_UP 14175All SZGR genes in this pathway
NAGASHIMA_NRG1_SIGNALING_UP 176123All SZGR genes in this pathway
NAGASHIMA_EGF_SIGNALING_UP 5840All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP 12672All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP 12073All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN 3123All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN 6244All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE 12380All SZGR genes in this pathway
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP 6445All SZGR genes in this pathway
XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP 3520All SZGR genes in this pathway
AMUNDSON_GENOTOXIC_SIGNATURE 10568All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN 6638All SZGR genes in this pathway
SIMBULAN_UV_RESPONSE_NORMAL_DN 3327All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP 142104All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP 283177All SZGR genes in this pathway
AMIT_EGF_RESPONSE_120_HELA 6947All SZGR genes in this pathway
AMIT_EGF_RESPONSE_120_MCF10A 4328All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_DN 169102All SZGR genes in this pathway
SWEET_KRAS_TARGETS_DN 6639All SZGR genes in this pathway
CHESLER_BRAIN_QTL_CIS 7551All SZGR genes in this pathway
LEE_LIVER_CANCER_ACOX1_DN 6539All SZGR genes in this pathway
SANA_TNF_SIGNALING_DN 9057All SZGR genes in this pathway
CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE 3721All SZGR genes in this pathway
DER_IFN_BETA_RESPONSE_UP 10267All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
DER_IFN_GAMMA_RESPONSE_UP 7145All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN 7748All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP 9258All SZGR genes in this pathway
VARELA_ZMPSTE24_TARGETS_DN 3818All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP 3427All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_2HR 5136All SZGR genes in this pathway
JACKSON_DNMT1_TARGETS_UP 7757All SZGR genes in this pathway
BURTON_ADIPOGENESIS_1 3324All SZGR genes in this pathway
BURTON_ADIPOGENESIS_9 9259All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
BILD_HRAS_ONCOGENIC_SIGNATURE 261166All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_UV 6243All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP 180114All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_UP 11580All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_DN 191123All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP 12692All SZGR genes in this pathway
GRADE_COLON_VS_RECTAL_CANCER_DN 5636All SZGR genes in this pathway
BOQUEST_STEM_CELL_DN 216143All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
YAGUE_PRETUMOR_DRUG_RESISTANCE_UP 85All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_UP 14798All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
RUIZ_TNC_TARGETS_UP 153107All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP 2215All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_DN 251151All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP 4030All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_2HR_DN 4933All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP 217131All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_GROUP1 13676All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_VIA_TSC1 2312All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 4633All SZGR genes in this pathway
HUANG_GATA2_TARGETS_DN 7252All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL 160106All SZGR genes in this pathway
ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF 222159All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1012772841A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-1442782841Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1813573641A,m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-203.1350356m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-375132513311Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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