Gene Page: CLASP2

Summary
GeneID  23122
Symbol  CLASP2
Synonyms  -
Description  cytoplasmic linker associated protein 2
See related  HGNC:17078|MIM:605853|HPRD:12054|
Locus tag  -
Gene type  protein-coding
Map location  3p22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0261 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MTOR0.940.95
MYH100.920.93
CLCN60.920.92
UBE2O0.920.93
LARP4B0.920.92
EIF4G30.910.92
HERC20.910.92
VPS530.910.91
ATRN0.910.93
ADAR0.910.92
Top 10 negatively co-expressed genes
AF347015.31-0.71-0.70
HIGD1B-0.70-0.72
AF347015.21-0.69-0.73
C1orf54-0.69-0.79
MT-CO2-0.68-0.68
FXYD1-0.68-0.66
GNG11-0.66-0.70
VAMP5-0.66-0.68
AC021016.1-0.65-0.65
S100A16-0.65-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI11290329 
GO:0008107galactoside 2-alpha-L-fucosyltransferase activityNAS11290329 
GO:0008017microtubule bindingIEA-
GO:0051010microtubule plus-end bindingIDA11290329 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007026negative regulation of microtubule depolymerizationIEA-
GO:0007026negative regulation of microtubule depolymerizationNAS11290329 
GO:0007163establishment or maintenance of cell polarityTAS15928712 
GO:0007049cell cycleIEA-
GO:0007067mitosisIEA-
GO:0051301cell divisionIEA-
GO:0031110regulation of microtubule polymerization or depolymerizationIMP11290329 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000777condensed chromosome kinetochoreIEA-
GO:0005794Golgi apparatusIDA11290329 
GO:0005794Golgi apparatusIEA-
GO:0005813centrosomeIEA-
GO:0005819spindleIEA-
GO:0005828kinetochore microtubuleTAS12837247 
GO:0005856cytoskeletonIEA-
GO:0005881cytoplasmic microtubuleIDA11290329 
GO:0005881cytoplasmic microtubuleIEA-
GO:0005737cytoplasmNAS11290329 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CLIP1CLIP | CLIP-170 | CLIP170 | CYLN1 | MGC131604 | RSNCAP-GLY domain containing linker protein 1-HPRD11290329 
CLIP2CLIP | CLIP-115 | CYLN2 | KIAA0291 | MGC11333 | WBSCR3 | WBSCR4 | WSCR3 | WSCR4CAP-GLY domain containing linker protein 2-HPRD,BioGRID11290329 
LXNECI | TCIlatexinAffinity Capture-MSBioGRID17353931 
MAPRE2EB1 | EB2 | RP1microtubule-associated protein, RP/EB family, member 2-HPRD15631994 
SMYD2HSKM-B | KMT3C | MGC119305 | ZMYND14SET and MYND domain containing 2Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_DN 189All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
KIM_GERMINAL_CENTER_T_HELPER_DN 2415All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
SANSOM_APC_TARGETS 212121All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
ROSS_LEUKEMIA_WITH_MLL_FUSIONS 7849All SZGR genes in this pathway
YAGI_AML_WITH_T_9_11_TRANSLOCATION 13087All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/9810781084m8hsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
miR-1389489541Ahsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-141/200a3063131A,m8hsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-18952958m8hsa-miR-18aUAAGGUGCAUCUAGUGCAGAUA
hsa-miR-18bUAAGGUGCAUCUAGUGCAGUUA
miR-200bc/4292152221A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-203.12652711Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-26162516321A,m8hsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-316566631A,m8hsa-miR-31AGGCAAGAUGCUGGCAUAGCUG
miR-3203603661Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-338335341m8hsa-miR-338brainUCCAGCAUCAGUGAUUUUGUUGA
miR-3813173231Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-496174180m8hsa-miR-496AUUACAUGGCCAAUCUC
hsa-miR-496AUUACAUGGCCAAUCUC
miR-539128412911A,m8hsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
hsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
miR-544406412m8hsa-miR-544AUUCUGCAUUUUUAGCAAGU
miR-7286292m8hsa-miR-7SZUGGAAGACUAGUGAUUUUGUUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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