Gene Page: ZFPM2

Summary ?
GeneID23414
SymbolZFPM2
SynonymsDIH3|FOG2|SRXY9|ZC2HC11B|ZNF89B|hFOG-2
Descriptionzinc finger protein, FOG family member 2
ReferenceMIM:603693|HGNC:HGNC:16700|Ensembl:ENSG00000169946|HPRD:04737|Vega:OTTHUMG00000164818
Gene typeprotein-coding
Map location8q23
Pascal p-value0.003
Fetal beta0.286
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg171543158106331166ZFPM22.17E-4-0.2960.036DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2816169chr1179210675ZFPM2234140.19trans
rs17572651chr1218943612ZFPM2234141.756E-5trans
rs17048849chr2129626025ZFPM2234140.03trans
rs2197597chr2129638077ZFPM2234140trans
rs2897468chr2129711721ZFPM2234140.01trans
rs16829545chr2151977407ZFPM2234141.301E-24trans
rs7584986chr2184111432ZFPM2234145.309E-7trans
rs6741060chr2217169088ZFPM2234140trans
rs9810143chr35060209ZFPM2234140.04trans
rs520325chr3165361016ZFPM2234140.17trans
snp_a-18157710ZFPM2234140.01trans
rs17020035chr493873810ZFPM2234140.06trans
rs17020058chr493915972ZFPM2234140.02trans
rs17020066chr493921055ZFPM2234140.02trans
rs2183142chr4159232695ZFPM2234140.04trans
rs4488887chr4177695833ZFPM2234140.09trans
rs1472616chr561026501ZFPM2234140.18trans
rs10474151chr584286402ZFPM2234140.03trans
rs3777174chr595280552ZFPM2234140.13trans
rs6893788chr595335085ZFPM2234140.13trans
rs10515234chr595336330ZFPM2234140.13trans
rs979348chr597074134ZFPM2234140.1trans
rs13191953chr624151042ZFPM2234140.15trans
rs12196880chr624313746ZFPM2234140.02trans
rs17149888chr724738371ZFPM2234140.11trans
rs10253181chr726563022ZFPM2234140.14trans
rs12706918chr780266147ZFPM2234140.18trans
rs2305128chr8120599486ZFPM2234140.14trans
rs2393316chr1059333070ZFPM2234147.989E-4trans
rs17124813chr10110347464ZFPM2234140.18trans
rs11061703chr121436977ZFPM2234140.15trans
rs7337967chr1353519044ZFPM2234140.2trans
rs4112777chr1399281457ZFPM2234146.886E-4trans
rs9989228chr1437809252ZFPM2234140.04trans
rs16955618chr1529937543ZFPM2234143.323E-24trans
rs2077735chr1558479024ZFPM2234140.01trans
rs4795850chr1732383815ZFPM2234140.11trans
rs4795851chr1732384050ZFPM2234140.11trans
rs12458173chr1831430166ZFPM2234140.02trans
rs6046679chr2020146874ZFPM2234140.01trans
rs1041786chr2122617710ZFPM2234143.919E-4trans
rs16986332chrX10958354ZFPM2234140.1trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 132101All SZGR 2.0 genes in this pathway
REACTOME HEMOSTASIS 466331All SZGR 2.0 genes in this pathway
SCHUETZ BREAST CANCER DUCTAL INVASIVE UP 351230All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER LMP DN 199124All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232154All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA UP 536340All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER F 5432All SZGR 2.0 genes in this pathway
OKUMURA INFLAMMATORY RESPONSE LPS 183115All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT DN 10267All SZGR 2.0 genes in this pathway
WANG SMARCE1 TARGETS DN 371218All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 UP 428266All SZGR 2.0 genes in this pathway
LIU SMARCA4 TARGETS 6439All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940425All SZGR 2.0 genes in this pathway
HOFFMANN IMMATURE TO MATURE B LYMPHOCYTE UP 4334All SZGR 2.0 genes in this pathway
CARD MIR302A TARGETS 7762All SZGR 2.0 genes in this pathway