Search results: The pahtway p4427 has 77 genes in the original annotation. Currently, there are 62 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
340719NANOS1EC_Rep1a | NOS-1 | NOS1 | SPGF12nanos homolog 1 (Drosophila)10q26.11CV:PGCnp
DMG:Nishioka_2013
1982EIF4G2AAG1 | DAP5 | NAT1 | P97eukaryotic translation initiation factor 4 gamma 211p15DMG:Jaffe_2016CompositeSet
Darnell FMRP targets
7465WEE1WEE1A | WEE1huWEE1 G2 checkpoint kinase11p15.4CV:PGCnp
Expression
PMID:cooccur
595CCND1BCL1 | D11S287E | PRAD1 | U21B31cyclin D111q13DMG:Jaffe_2016
Network
PMID:cooccur
894CCND2KIAK0002 | MPPH3cyclin D212p13CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
PMID:cooccur
55810FOXJ2FHXforkhead box J212p13.31CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
25946ZNF385AHZF | RZF | ZFP385 | ZNF385zinc finger protein 385A12q13.13CV:PGCnp
DMG:Wockner_2014
23014FBXO21FBX21F-box protein 2112q24.22CV:PGCnp
8600TNFSF11CD254 | ODF | OPGL | OPTB2 | RANKL | TNLG6B | TRANCE | hRANKL2 | sOdftumor necrosis factor superfamily member 1113q14CV:PGCnp
DMG:Wockner_2014
Network
5925RB1OSRC | PPP1R130 | RB | p105-Rb | pRb | pp110retinoblastoma 113q14.2CV:PGCnp
Network
PMID:cooccur
2290FOXG1BF1 | BF2 | FHKL3 | FKH2 | FKHL1 | FKHL2 | FKHL3 | FKHL4 | FOXG1A | FOXG1B | FOXG1C | HBF-1 | HBF-2 | HBF-3 | HBF-G2 | HBF2 | HFK1 | HFK2 | HFK3 | KHL2 | QINforkhead box G114q13DMG:Jaffe_2016
GO_Annotation
GSMA_I
PMID:cooccur
5926ARID4ARBBP-1 | RBBP1 | RBP-1 | RBP1AT-rich interaction domain 4A14q23.1CV:PGCnp
7026NR2F2ARP1 | CHTD4 | COUPTFB | COUPTFII | NF-E3 | NR2F1 | SVP40 | TFCOUP2nuclear receptor subfamily 2 group F member 215q26CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GO_Annotation
5930RBBP6MY038 | P2P-R | PACT | RBQ-1 | SNAMAretinoblastoma binding protein 616p12.2CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
GSMA_IIE
5934RBL2P130 | Rb2retinoblastoma-like 216q12.2CV:PGCnp
1949EFNB3EFL6 | EPLG8 | LERK8ephrin-B317p13.1CV:PGCnp
GO_Annotation
PMID:cooccur
Potential synaptic genes
4335MNTMAD6 | MXD6 | ROX | bHLHd3MAX network transcriptional repressor17p13.3CV:PGCnp
DMG:Jaffe_2016
DMG:Nishioka_2013
DMG:Wockner_2014
PMID:cooccur
1655DDX5G17P1 | HLR1 | HUMP68 | p68DEAD-box helicase 517q21CV:PGCnp
DMG:Wockner_2014
Network
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
5878RAB5CL1880 | RAB5CL | RAB5L | RABLRAB5C, member RAS oncogene family17q21.2CV:PGCnp
DMG:vanEijk_2014
INTRACELLULAR TRAFFICKING
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
CompositeSet
6774STAT3ADMIO | APRF | HIESsignal transducer and activator of transcription 3 (acute-phase response factor)17q21.31CV:PGCnp
CV:PheWAS
DMG:vanEijk_2014
GO_Annotation
Network
PMID:cooccur
7484WNT9BWNT14B | WNT15wingless-type MMTV integration site family member 9B17q21.32CV:PGCnp
3838KPNA2IPOA1 | QIP2 | RCH1 | SRP1-alpha | SRP1alphakaryopherin subunit alpha 217q24.2CV:PGCnp
DMG:Nishioka_2013
Network
8932MBD2DMTase | NY-CO-41methyl-CpG binding domain protein 218q21CV:PGCnp
PMID:cooccur
Chromatin Remodeling Genes
4092SMAD7CRCS3 | MADH7 | MADH8SMAD family member 718q21.1CV:PGCnp
DNM:Fromer_2014
CompositeSet
1786DNMT1ADCADN | AIM | CXXC9 | DNMT | HSN1E | MCMT | m.HsaIDNA (cytosine-5-)-methyltransferase 119p13.2CV:PGCnp
DMG:Wockner_2014
DNM:Gulsuner_2013
PMID:cooccur
Ascano FMRP targets
Chromatin Remodeling Genes
3726JUNBAP-1jun B proto-oncogene19p13.2CV:PGCnp
DMG:Jaffe_2016
PMID:cooccur
57616TSHZ3TSH3 | ZNF537teashirt zinc finger homeobox 319q12CV:GWASdb
CV:PGCnp
Ascano FMRP targets
22887FOXJ3-forkhead box J31p34.2CV:PGCnp
DMG:Jaffe_2016
23435TARDBPALS10 | TDP-43TAR DNA binding protein1p36.22CV:PGCnp
PMID:cooccur
51742ARID4BBCAA | BRCAA1 | RBBP1L1 | RBP1L1 | SAP180AT-rich interaction domain 4B1q42.3CV:PGCnp
DMG:Wockner_2014
4661MYT1C20orf36 | MTF1 | MYTI | NZF2 | PLPB1 | ZC2HC4Amyelin transcription factor 120q13.33CV:PGCnp
DMG:Wockner_2014
Expression
GO_Annotation
PMID:cooccur
6664SOX11MRD27SRY-box 112p25CV:PGCnp
GO_Annotation
PMID:cooccur
26122EPC2EPC-LIKEenhancer of polycomb homolog 22q23.1CV:PGC128
CV:PGCnp
CV:PheWAS
GSMA_I
GSMA_IIA
4760NEUROD1BETA2 | BHF-1 | MODY6 | NEUROD | bHLHa3neuronal differentiation 12q32CV:PGCnp
GO_Annotation
Network
PMID:cooccur
2043EPHA4HEK8 | SEK | TYRO1EPH receptor A42q36.1CV:PGCnp
GSMA_IIA
GSMA_IIE
PMID:cooccur
TYROSINE KINASE SIGNALING
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
7048TGFBR2AAT3 | FAA3 | LDS1B | LDS2 | LDS2B | MFS2 | RIIC | TAAD2 | TGFR-2 | TGFbeta-RIItransforming growth factor beta receptor II3p22CV:PGCnp
GO_Annotation
GSMA_I
PMID:cooccur
5915RARBHAP | MCOPS12 | NR1B2 | RRB2retinoic acid receptor beta3p24.2CV:GWASdb
CV:PGCnp
GSMA_I
5217PFN2D3S1319E | PFLprofilin 23q25.1NetworkSTRUCTURAL PLASTICITY
CompositeSet
22865SLITRK3-SLIT and NTRK like family member 33q26.1CV:PGCnp
DMG:Wockner_2014
GO_Annotation
9575CLOCKKAT13D | bHLHe8clock circadian regulator4q12Association
CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
63973NEUROG2Atoh4 | Math4A | NGN2 | bHLHa8 | ngn-2neurogenin 24q25DMG:Jaffe_2016
GO_Annotation
PMID:cooccur
4131MAP1BFUTSCH | MAP5 | PPP1R102microtubule associated protein 1B5q13CV:PGCnp
GO_Annotation
PMID:cooccur
STRUCTURAL PLASTICITY
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_clathrin
G2Cdb.human_mGluR5
G2Cdb.human_Synaptosome
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
Potential synaptic genes
7422VEGFAMVCD1 | VEGF | VPFvascular endothelial growth factor A6p12CV:PGCnp
DEG:Maycox_2009
GO_Annotation
GSMA_IIE
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSP
Potential synaptic genes
23328SASH1SH3D6A | dJ323M4 | dJ323M4.1SAM and SH3 domain containing 16q24.3CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
28514DLL1DELTA1 | DL1 | Deltadelta-like 1 (Drosophila)6q27CV:PGCnp
221895JAZF1TIP27 | ZNF802JAZF zinc finger 17p15.2-p15.1CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
7291TWIST1ACS3 | BPES2 | BPES3 | CRS | CRS1 | CSO | SCS | TWIST | bHLHa38twist family bHLH transcription factor 17p21.2CV:GWASdb
CV:PGCnp
DMG:vanEijk_2014
GO_Annotation
3984LIMK1LIMK | LIMK-1LIM domain kinase 17q11.23CNV:YES
CV:PGCnp
DEG:Zhao_2015
GO_Annotation
Network
PMID:cooccur
1021CDK6MCPH12 | PLSTIREcyclin-dependent kinase 67q21-q22CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
Network
PMID:cooccur
7994KAT6AMOZ | MRD32 | MYST-3 | MYST3 | RUNXBP2 | ZC2HC6A | ZNF220lysine acetyltransferase 6A8p11CV:PGCnp
DMG:Jaffe_2016
29883CNOT7CAF1 | Caf1a | hCAF-1CCR4-NOT transcription complex subunit 78p22-p21.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
GSMA_IIA
GSMA_IIE
9821RB1CC1ATG17 | CC1 | FIP200 | PPP1R131RB1 inducible coiled-coil 18q11CV:PGCnp
DMG:Wockner_2014
DNM:Xu_2012
PMID:cooccur
CompositeSet
79776ZFHX4ZFH4 | ZHF4zinc finger homeobox 48q21.11CV:PGCnp
1875E2F5E2F-5E2F transcription factor 58q21.2CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
23414ZFPM2DIH3 | FOG2 | SRXY9 | ZC2HC11B | ZNF89B | hFOG-2zinc finger protein, FOG family member 28q23CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
50807ASAP1AMAP1 | CENTB4 | DDEF1 | PAG2 | PAP | ZG14PArfGAP with SH3 domain, ankyrin repeat and PH domain 18q24.1-q24.2CV:GWASdb
CV:PGCnp
DNM:Fromer_2014
CompositeSet
22882ZHX2AFR1 | RAFzinc fingers and homeoboxes 28q24.13CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
7436VLDLRCAMRQ1 | CARMQ1 | CHRMQ1 | VLDLRCHvery low density lipoprotein receptor9p24CV:PGCnp
GO_Annotation
Network
PMID:cooccur
Ascano FMRP targets
6096RORBNR1F2 | ROR-BETA | RZR-BETA | RZRB | bA133M9.1RAR related orphan receptor B9q22CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
5537PPP6CPP6 | PP6Cprotein phosphatase 6 catalytic subunit9q33.3CV:PGCnp
DMG:Nishioka_2013
Expression
5931RBBP7RbAp46retinoblastoma binding protein 7Xp22.2CV:PGCnpChromatin Remodeling Genes
51114ZDHHC9CGI89 | CXorf11 | DHHC9 | MMSA1 | MRXSZ | ZDHHC10 | ZNF379 | ZNF380zinc finger DHHC-type containing 9Xq26.1CV:PGCnp
PMID:cooccur