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Gene Page: STAT3

Summary

GeneID

6774

Symbol

STAT3

Synonyms

APRF|FLJ20882|HIES|MGC16063

Description

signal transducer and activator of transcription 3 (acute-phase response factor)

Locus tag

Gene type

protein-coding

Map location

17q21.31

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.046

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SPG20

0.87

0.82

ATG4C

0.87

0.85

RNF13

0.87

0.85

LAMP2

0.85

LIPA

0.85

MOSPD2

0.85

0.77

REEP3

0.84

0.78

TTC35

0.84

0.88

KIAA0494

0.83

0.82

GCLC

0.82

Top 10 negatively co-expressed genes

SH2B2

-0.51

-0.57

SH3BP2

-0.50

-0.54

HYAL2

-0.49

-0.56

TRAF4

-0.47

-0.51

CCDC28B

-0.46

-0.53

KIAA1949

-0.46

-0.39

C21orf30

-0.46

-0.38

WDR86

-0.46

-0.47

ISLR2

-0.45

-0.28

PAFAH1B3

-0.45

-0.43

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004871

signal transducer activity

IEA

GO:0003700

transcription factor activity

IEA

GO:0003700

transcription factor activity

TAS

7512451 |8675499

GO:0005062

hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity

TAS

7512451

GO:0005509

calcium ion binding

IEA

GO:0005515

protein binding

IEA

GO:0008134

transcription factor binding

IPI

15664994

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007399

nervous system development

TAS

neurite (GO term level: 5)

10205054

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

TAS

8675499

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0007259

JAK-STAT cascade

TAS

15664994

GO:0007165

signal transduction

IEA

GO:0007165

signal transduction

TAS

7512451 |10205054

GO:0006928

cell motion

TAS

9670957

GO:0019221

cytokine-mediated signaling pathway

NAS

15664994

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

12444102

GO:0005634

nucleus

IEA

GO:0005730

nucleolus

IDA

18029348

GO:0005737

cytoplasm

TAS

7512451

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
A2M	CPAMD5 \| DKFZp779B086 \| FWP007 \| S863-7	alpha-2-macroglobulin	An unspecified isoform of STAT3 binds APRE.	BIND	15950906
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD,BioGRID	11751884
BHLHB2	DEC1 \| SHARP-2 \| STRA13 \| Stra14 \| bHLHe40	basic helix-loop-helix domain containing, class B, 2	-	HPRD	15223310
			STRA13 interacts with STAT3-beta.	BIND	15223310
			STRA13 interacts with STAT3-alpha.	BIND	15223310
BMX	ETK \| PSCTK2 \| PSCTK3	BMX non-receptor tyrosine kinase	-	HPRD,BioGRID	10688651
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD	11163768
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	An unspecified isoform of STAT3 binds to Cyclin D1 promoter.	BIND	15950906
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	-	HPRD,BioGRID	11279133
CCR2	CC-CKR-2 \| CCR2A \| CCR2B \| CD192 \| CKR2 \| CKR2A \| CKR2B \| CMKBR2 \| MCP-1-R	chemokine (C-C motif) receptor 2	Affinity Capture-Western	BioGRID	11350939
CCR5	CC-CKR-5 \| CCCKR5 \| CD195 \| CKR-5 \| CKR5 \| CMKBR5	chemokine (C-C motif) receptor 5	Affinity Capture-Western	BioGRID	11350939
CDKN1A	CAP20 \| CDKN1 \| CIP1 \| MDA-6 \| P21 \| SDI1 \| WAF1 \| p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	-	HPRD,BioGRID	10764767
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	Affinity Capture-Western	BioGRID	11239394
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	Stat3 was acetylated by CBP. This interaction was modeled on a demonstrated interaction between human Stat3 and CBP from an unspecified species.	BIND	15653507
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	Affinity Capture-Western	BioGRID	10358079 \|15485908
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA		Tyrosine phophorylated EGFR interacts with STAT3.	BIND	12873986
EIF2AK2	EIF2AK1 \| MGC126524 \| PKR \| PRKR	eukaryotic translation initiation factor 2-alpha kinase 2	-	HPRD,BioGRID	11350938
ELP2	FLJ10879 \| SHINC-2 \| STATIP1 \| StIP	elongation protein 2 homolog (S. cerevisiae)	-	HPRD,BioGRID	10954736
EP300	KAT3B \| p300	E1A binding protein p300	Stat3 interacts with p300.	BIND	15653507
EP300	KAT3B \| p300	E1A binding protein p300	-	HPRD,BioGRID	10205054
EPHA5	CEK7 \| EHK1 \| HEK7 \| TYRO4	EPH receptor A5	Affinity Capture-Western	BioGRID	15485908
ERBB2	CD340 \| HER-2 \| HER-2/neu \| HER2 \| NEU \| NGL \| TKR1	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Affinity Capture-Western	BioGRID	11940572
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	Affinity Capture-Western	BioGRID	11429412
FER	TYK3	fer (fps/fes related) tyrosine kinase	-	HPRD	10878010
FER	TYK3	fer (fps/fes related) tyrosine kinase	-	HPRD	10878010 \|12738762
FES	FPS	feline sarcoma oncogene	-	HPRD,BioGRID	9714332
FOS	AP-1 \| C-FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	An unspecified isoform of STAT3 binds to c-fos promoter.	BIND	15950906
FOXM1	FKHL16 \| FOXM1B \| HFH-11 \| HFH11 \| HNF-3 \| INS-1 \| MPHOSPH2 \| MPP-2 \| MPP2 \| PIG29 \| TGT3 \| TRIDENT	forkhead box M1	-	HPRD	11861839
FRAP1	FLJ44809 \| FRAP \| FRAP2 \| MTOR \| RAFT1 \| RAPT1	FK506 binding protein 12-rapamycin associated protein 1	Affinity Capture-Western Reconstituted Complex	BioGRID	10660304 \|15522880
GHR	GHBP	growth hormone receptor	-	HPRD,BioGRID	8923468
GTF2I	BAP-135 \| BAP135 \| BTKAP1 \| DIWS \| FLJ38776 \| FLJ56355 \| IB291 \| SPIN \| TFII-I \| WBS \| WBSCR6	general transcription factor II, i	-	HPRD,BioGRID	9584171
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	Stat3 interacts with HDAC1.	BIND	15653507
HDAC2	RPD3 \| YAF1	histone deacetylase 2	Stat3 interacts with HDAC2.	BIND	15653507
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	Stat3 interacts with HDAC3.	BIND	15653507
HNF1A	HNF1 \| LFB1 \| MODY3 \| TCF1	HNF1 homeobox A	-	HPRD,BioGRID	11134330
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	12559950
IFNAR1	AVP \| IFN-alpha-REC \| IFNAR \| IFNBR \| IFRC	interferon (alpha, beta and omega) receptor 1	-	HPRD,BioGRID	8626489
IL1RAP	C3orf13 \| FLJ37788 \| IL-1RAcP \| IL1R3	interleukin 1 receptor accessory protein	-	HPRD,BioGRID	9923604
IL23R	-	interleukin 23 receptor	-	HPRD	12023369
IL2RA	CD25 \| IDDM10 \| IL2R \| TCGFR	interleukin 2 receptor, alpha	-	HPRD	10602027
IL2RB	CD122 \| P70-75	interleukin 2 receptor, beta	-	HPRD,BioGRID	10602027
IL6R	CD126 \| IL-6R-1 \| IL-6R-alpha \| IL6RA \| MGC104991	interleukin 6 receptor	-	HPRD,BioGRID	10982829
IL6ST	CD130 \| CDw130 \| GP130 \| GP130-RAPS \| IL6R-beta	interleukin 6 signal transducer (gp130, oncostatin M receptor)	-	HPRD,BioGRID	12361954
IL6ST	CD130 \| CDw130 \| GP130 \| GP130-RAPS \| IL6R-beta		gp130 interacts with an unspecified isoform of Stat3.	BIND	12361954
JAK1	JAK1A \| JAK1B \| JTK3	Janus kinase 1 (a protein tyrosine kinase)	-	HPRD,BioGRID	11722592
JAK2	JTK10	Janus kinase 2 (a protein tyrosine kinase)	-	HPRD	10925297
JAK3	JAK-3 \| JAK3_HUMAN \| JAKL \| L-JAK \| LJAK	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	-	HPRD,BioGRID	10037026
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD,BioGRID	10490649
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K(lysine) acetyltransferase 5	-	HPRD,BioGRID	12551922
KHDRBS1	FLJ34027 \| Sam68 \| p62	KH domain containing, RNA binding, signal transduction associated 1	-	HPRD,BioGRID	11585385
LCK	YT16 \| p56lck \| pp58lck	lymphocyte-specific protein tyrosine kinase	-	HPRD	10825200
LEP	FLJ94114 \| OB \| OBS	leptin	Reconstituted Complex	BioGRID	12824284
LEPR	CD295 \| OBR	leptin receptor	-	HPRD	8608603
MET	AUTS9 \| HGFR \| RCCP2 \| c-Met	met proto-oncogene (hepatocyte growth factor receptor)	-	HPRD,BioGRID	9440692
MYOD1	MYF3 \| MYOD \| PUM \| bHLHc1	myogenic differentiation 1	-	HPRD,BioGRID	12947115
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	nuclear receptor coactivator 1	-	HPRD,BioGRID	11773079
NDUFA13	B16.6 \| CDA016 \| CGI-39 \| GRIM-19 \| GRIM19	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	GRIM-19 interacts with Stat3.	BIND	12628925
NDUFA13	B16.6 \| CDA016 \| CGI-39 \| GRIM-19 \| GRIM19	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	-	HPRD,BioGRID	12867595
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	-	HPRD,BioGRID	12057007
NLK	DKFZp761G1211 \| FLJ21033	nemo-like kinase	-	HPRD	15764709
NMI	-	N-myc (and STAT) interactor	Nmi interacts with Stat3	BIND	9989503
NMI	-	N-myc (and STAT) interactor	-	HPRD,BioGRID	9989503
NR3C1	GCCR \| GCR \| GR \| GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-	HPRD,BioGRID	9388192 \|14522952
PDIA3	ER60 \| ERp57 \| ERp60 \| ERp61 \| GRP57 \| GRP58 \| HsT17083 \| P58 \| PI-PLC	protein disulfide isomerase family A, member 3	-	HPRD,BioGRID	12060494
PIAS3	FLJ14651 \| ZMIZ5	protein inhibitor of activated STAT, 3	-	HPRD	11429412 \|12804609
PIAS3	FLJ14651 \| ZMIZ5	protein inhibitor of activated STAT, 3	-	HPRD,BioGRID	11429412
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	-	HPRD,BioGRID	12506013
PRKCB	MGC41878 \| PKC-beta \| PKCB \| PRKCB1 \| PRKCB2	protein kinase C, beta	An unspecified isoform of PKC-beta interacts with Stat3.	BIND	10446219
PRKCD	MAY1 \| MGC49908 \| PKCD \| nPKC-delta	protein kinase C, delta	PKC-delta interacts with Stat3.	BIND	10446219
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	Affinity Capture-Western	BioGRID	10925297
PTPN11	BPTP3 \| CFC \| MGC14433 \| NS1 \| PTP-1D \| PTP2C \| SH-PTP2 \| SH-PTP3 \| SHP2	protein tyrosine phosphatase, non-receptor type 11	-	HPRD,BioGRID	11594781
PTPN2	PTPT \| TC-PTP \| TCELLPTP \| TCPTP	protein tyrosine phosphatase, non-receptor type 2	-	HPRD,BioGRID	12359225
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	-	HPRD,BioGRID	11021801
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	-	HPRD,BioGRID	12057007
RET	CDHF12 \| HSCR1 \| MEN2A \| MEN2B \| MTC1 \| PTC \| RET-ELE1 \| RET51	ret proto-oncogene	-	HPRD,BioGRID	11536047 \|12637586 \|15485908
RPA2	REPA2 \| RPA32	replication protein A2, 32kDa	-	HPRD,BioGRID	10875894
SMAD1	BSP1 \| JV4-1 \| JV41 \| MADH1 \| MADR1	SMAD family member 1	Affinity Capture-Western	BioGRID	10205054
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	-	HPRD,BioGRID	8657134
STAP2	BKS \| FLJ20234	signal transducing adaptor family member 2	-	HPRD	12540842
STAT1	DKFZp686B04100 \| ISGF-3 \| STAT91	signal transducer and activator of transcription 1, 91kDa	-	HPRD,BioGRID	12070153
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	Stat3 interacts with itself to form a homodimer.	BIND	15653507
SYK	DKFZp313N1010 \| FLJ25043 \| FLJ37489	spleen tyrosine kinase	-	HPRD	10825200
TRIP10	CIP4 \| HSTP \| STOT \| STP	thyroid hormone receptor interactor 10	Affinity Capture-Western Reconstituted Complex	BioGRID	15163742
TSHR	CHNG1 \| LGR3 \| MGC75129 \| hTSHR-I	thyroid stimulating hormone receptor	-	HPRD,BioGRID	10809230
TSLP	-	thymic stromal lymphopoietin	-	HPRD	10570284 \|11418668
ZNF467	EZI \| Zfp467	zinc finger protein 467	-	HPRD	12426389

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY	155	105	All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	67	57	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER	70	56	All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA	60	47	All SZGR genes in this pathway
BIOCARTA_BIOPEPTIDES_PATHWAY	45	35	All SZGR genes in this pathway
BIOCARTA_EGF_PATHWAY	31	25	All SZGR genes in this pathway
BIOCARTA_ERK_PATHWAY	28	22	All SZGR genes in this pathway
BIOCARTA_IL6_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_IL10_PATHWAY	17	14	All SZGR genes in this pathway
BIOCARTA_IL22BP_PATHWAY	16	12	All SZGR genes in this pathway
BIOCARTA_PDGF_PATHWAY	32	25	All SZGR genes in this pathway
BIOCARTA_HER2_PATHWAY	22	17	All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY	37	30	All SZGR genes in this pathway
BIOCARTA_TPO_PATHWAY	24	17	All SZGR genes in this pathway
ST_G_ALPHA_I_PATHWAY	35	29	All SZGR genes in this pathway
ST_STAT3_PATHWAY	11	10	All SZGR genes in this pathway
PID_GMCSF_PATHWAY	37	31	All SZGR genes in this pathway
PID_IL27_PATHWAY	26	20	All SZGR genes in this pathway
PID_PTP1B_PATHWAY	52	40	All SZGR genes in this pathway
PID_IL12_2PATHWAY	63	54	All SZGR genes in this pathway
PID_TCPTP_PATHWAY	43	33	All SZGR genes in this pathway
PID_HDAC_CLASSI_PATHWAY	66	50	All SZGR genes in this pathway
PID_IL2_1PATHWAY	55	43	All SZGR genes in this pathway
PID_CXCR4_PATHWAY	102	78	All SZGR genes in this pathway
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY	35	29	All SZGR genes in this pathway
PID_IFNG_PATHWAY	40	34	All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY	105	78	All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY	44	35	All SZGR genes in this pathway
PID_IL6_7_PATHWAY	47	40	All SZGR genes in this pathway
PID_PDGFRB_PATHWAY	129	103	All SZGR genes in this pathway
PID_TRKR_PATHWAY	62	48	All SZGR genes in this pathway
PID_IL23_PATHWAY	37	30	All SZGR genes in this pathway
PID_KIT_PATHWAY	52	40	All SZGR genes in this pathway
PID_RAC1_PATHWAY	54	37	All SZGR genes in this pathway
PID_HES_HEY_PATHWAY	48	39	All SZGR genes in this pathway
PID_IL12_STAT4_PATHWAY	33	29	All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF	217	167	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT	78	59	All SZGR genes in this pathway
REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING	24	19	All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE	137	105	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE	127	88	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_MUTANTS	30	20	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS	19	12	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_MUTANTS	44	29	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF	122	93	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	95	76	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS	107	86	All SZGR genes in this pathway
REACTOME_IL_6_SIGNALING	11	9	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	270	204	All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP	183	119	All SZGR genes in this pathway
SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN	62	35	All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP	1382	904	All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN	320	184	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	455	304	All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP	305	185	All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN	406	230	All SZGR genes in this pathway
HUMMEL_BURKITTS_LYMPHOMA_DN	15	10	All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP	293	179	All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN	51	35	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP	170	114	All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN	394	258	All SZGR genes in this pathway
JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP	58	44	All SZGR genes in this pathway
NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP	29	20	All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP	181	108	All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_UP	88	58	All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2	127	92	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP	134	93	All SZGR genes in this pathway
DAUER_STAT3_TARGETS_UP	49	35	All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	584	395	All SZGR genes in this pathway
OZEN_MIR125B1_TARGETS	25	15	All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS	988	594	All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS	290	172	All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS	734	436	All SZGR genes in this pathway
BENPORATH_NOS_TARGETS	179	105	All SZGR genes in this pathway
UEDA_CENTRAL_CLOCK	88	62	All SZGR genes in this pathway
BROCKE_APOPTOSIS_REVERSED_BY_IL6	144	98	All SZGR genes in this pathway
TENEDINI_MEGAKARYOCYTE_MARKERS	66	48	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	555	346	All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	87	67	All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_1_UP	46	29	All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN	141	99	All SZGR genes in this pathway
SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER	49	30	All SZGR genes in this pathway
KAAB_FAILED_HEART_VENTRICLE_DN	41	28	All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_DN	96	71	All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_UP	49	40	All SZGR genes in this pathway
HILLION_HMGA1_TARGETS	90	71	All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS	92	68	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED	1022	619	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED	1229	713	All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN	409	268	All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_UV	62	43	All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP	226	164	All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP	461	298	All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN	154	101	All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_UP	115	80	All SZGR genes in this pathway
OUYANG_PROSTATE_CANCER_PROGRESSION_UP	20	14	All SZGR genes in this pathway
MATZUK_CENTRAL_FOR_FEMALE_FERTILITY	29	25	All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_C	69	49	All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES	389	245	All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN	207	139	All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP	242	159	All SZGR genes in this pathway
GABRIELY_MIR21_TARGETS	289	187	All SZGR genes in this pathway
CARD_MIR302A_TARGETS	77	62	All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN	116	74	All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_UP	194	133	All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP	682	433	All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_UP	221	120	All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL	160	106	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	1209	1215	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	1208	1215	1A,m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	1208	1215	1A,m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-125/351	1438	1445	1A,m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	1438	1445	1A,m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-17-5p/20/93.mr/106/519.d	448	454	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-21	1946	1952	m8	hsa-miR-21^brain	UAGCUUAUCAGACUGAUGUUGA
miR-21	1946	1952	m8	hsa-miR-590	GAGCUUAUUCAUAAAAGUGCAG
miR-410	2405	2412	1A,m8	hsa-miR-410	AAUAUAACACAGAUGGCCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.