Gene Page: NR2F2

Summary
GeneID  7026
Symbol  NR2F2
Synonyms  ARP1|COUP-TFII|COUPTFB|MGC117452|SVP40|TFCOUP2
Description  nuclear receptor subfamily 2, group F, member 2
See related  HGNC:7976|MIM:107773|Ensembl:ENSG00000185551|HPRD:00139|
Locus tag  -
Gene type  protein-coding
Map location  15q26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003706ligand-regulated transcription factor activityTAS8530078 
GO:0003707steroid hormone receptor activityIEA-
GO:0003714transcription corepressor activityTAS1899293 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001764neuron migrationIEAneuron (GO term level: 8)-
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0007519skeletal muscle developmentIEAneuron (GO term level: 8)-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006357regulation of transcription from RNA polymerase II promoterTAS1899293 
GO:0006350transcriptionIEA-
GO:0009956radial pattern formationIEA-
GO:0009952anterior/posterior pattern formationIEA-
GO:0007165signal transductionTAS1899293 
GO:0006629lipid metabolic processTAS1899293 
GO:0048514blood vessel morphogenesisIEA-
GO:0060173limb developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005634nucleusTAS1899293 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCL11ABCL11A-L | BCL11A-S | BCL11A-XL | CTIP1 | EVI9 | FLJ10173 | FLJ34997 | HBFQTL5 | KIAA1809 | ZNF856B-cell CLL/lymphoma 11A (zinc finger protein)-HPRD10744719 
BCL11BCTIP-2 | CTIP2 | RIT1 | hRIT1-alphaB-cell CLL/lymphoma 11B (zinc finger protein)-HPRD10744719 
HDAC1DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 1-HPRD,BioGRID10704340 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinaseReconstituted Complex
Two-hybrid		BioGRID8910285 
MYOD1MYF3 | MYOD | PUM | bHLHc1myogenic differentiation 1-HPRD,BioGRID9826778 
NR2F6EAR-2 | EAR2 | ERBAL2nuclear receptor subfamily 2, group F, member 6-HPRD,BioGRID10318855 
PIAS1DDXBP1 | GBP | GU/RH-II | MGC141878 | MGC141879 | ZMIZ3protein inhibitor of activated STAT, 1-HPRD15611122 |15666827 
SQSTM1A170 | OSIL | PDB3 | ZIP3 | p60 | p62 | p62Bsequestosome 1-HPRD8910285 
TRIM24PTC6 | RNF82 | TF1A | TIF1 | TIF1A | TIF1ALPHA | hTIF1tripartite motif-containing 24-HPRD9115274 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_TELOMERASE_PATHWAY 6848All SZGR genes in this pathway
PID_HNF3A_PATHWAY 4429All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 7253All SZGR genes in this pathway
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP 205140All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP 6437All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP 8251All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN 4834All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_UP 5127All SZGR genes in this pathway
STREICHER_LSM1_TARGETS_UP 4434All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM 15993All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER 8864All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN 87All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
WU_CELL_MIGRATION 184114All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN 10364All SZGR genes in this pathway
BECKER_TAMOXIFEN_RESISTANCE_DN 5237All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN 162102All SZGR genes in this pathway
RADMACHER_AML_PROGNOSIS 7852All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_DN 138All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
PAL_PRMT5_TARGETS_UP 203135All SZGR genes in this pathway
RAMASWAMY_METASTASIS_DN 6147All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_UP 175116All SZGR genes in this pathway
KANG_FLUOROURACIL_RESISTANCE_UP 2215All SZGR genes in this pathway
ZHU_CMV_8_HR_DN 5340All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN 318220All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D8 4029All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
HOWLIN_CITED1_TARGETS_1_UP 3525All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_DN 10563All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_DN 12081All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP 12692All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_DN 5944All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_UP 4025All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
MIKKELSEN_IPS_WITH_HCP_H3K27ME3 10276All SZGR genes in this pathway
MIKKELSEN_IPS_ICP_WITH_H3K27ME3 5432All SZGR genes in this pathway
FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP 3623All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
MIKKELSEN_ES_HCP_WITH_H3K27ME3 4130All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN 10367All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_DN 11573All SZGR genes in this pathway
CARD_MIR302A_TARGETS 7762All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 403240All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL 160106All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101108710931Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-144108610931A,m8hsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1503313381A,m8hsa-miR-150UCUCCCAACCCUUGUACCAGUG
miR-1551952011Ahsa-miR-155UUAAUGCUAAUCGUGAUAGGGG
miR-194991051Ahsa-miR-194UGUAACAGCAACUCCAUGUGGA
miR-30-5p102710331Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-369-3p9179241A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-3749189251A,m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-376c3984051A,m8hsa-miR-376cAACAUAGAGGAAAUUCCACG
miR-3818969021Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-41011341140m8hsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-4317998051Ahsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-93.hd/291-3p/294/295/302/372/373/5206056111Ahsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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