Gene Page: FRZB

Summary
GeneID  2487
Symbol  FRZB
Synonyms  FRE|FRITZ|FRP-3|FRZB-1|FRZB-PEN|FRZB1|FZRB|SFRP3|SRFP3|hFIZ
Description  frizzled-related protein
See related  HGNC:3959|MIM:605083|Ensembl:ENSG00000162998|HPRD:07282|
Locus tag  -
Gene type  protein-coding
Map location  2qter
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.382 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0017147Wnt-protein bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001501skeletal system developmentTAS8824257 
GO:0007275multicellular organismal developmentIEA-
GO:0030178negative regulation of Wnt receptor signaling pathwayISS-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionTAS9096311 
GO:0016020membraneTAS8824257 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
WNT_SIGNALING 8971All SZGR genes in this pathway
WINTER_HYPOXIA_DN 5230All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_DN 10459All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN 11458All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN 5142All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_UP 209139All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_UP 7749All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN 10371All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP 236139All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_A 10063All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN 3624All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_HP_UP 4926All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
MACLACHLAN_BRCA1_TARGETS_DN 1612All SZGR genes in this pathway
SANSOM_WNT_PATHWAY_REQUIRE_MYC 5843All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION 8159All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP 14985All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP 165118All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN 13892All SZGR genes in this pathway
DAVIES_MULTIPLE_MYELOMA_VS_MGUS_UP 1310All SZGR genes in this pathway
FINAK_BREAST_CANCER_SDPP_SIGNATURE 2611All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
CROONQUIST_IL6_DEPRIVATION_DN 9869All SZGR genes in this pathway
ZHAN_V1_LATE_DIFFERENTIATION_GENES_DN 1513All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP 6242All SZGR genes in this pathway
FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN 2614All SZGR genes in this pathway
FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN 8053All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2_M 216124All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
ROLEF_GLIS3_TARGETS 3729All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
NABA_SECRETED_FACTORS 344197All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-33855611Ahsa-miR-338brainUCCAGCAUCAGUGAUUUUGUUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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