Gene Page: MSR1

Summary
GeneID  4481
Symbol  MSR1
Synonyms  CD204|SCARA1|SR-A|phSR1|phSR2
Description  macrophage scavenger receptor 1
See related  HGNC:7376|MIM:153622|Ensembl:ENSG00000038945|HPRD:01092|
Locus tag  -
Gene type  protein-coding
Map location  8p22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SPAG90.840.85
RPA10.820.79
ARHGAP190.820.79
CTNND10.810.78
SP10.810.80
RCC20.800.77
CRKL0.800.81
DUSP160.800.81
PHF80.800.80
KIAA19580.800.83
Top 10 negatively co-expressed genes
AF347015.21-0.54-0.61
IFI27-0.54-0.59
CXCL14-0.52-0.58
AF347015.31-0.52-0.56
MT-CO2-0.52-0.57
MYL3-0.49-0.54
FXYD1-0.49-0.53
HIGD1B-0.49-0.53
IL32-0.48-0.55
AF347015.8-0.48-0.53
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0005044scavenger receptor activityIEA-
GO:0005044scavenger receptor activityTAS2251254 
GO:0005515protein bindingIPI17237231 
GO:0005319lipid transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0042953lipoprotein transportIEA-
GO:0006898receptor-mediated endocytosisIEA-
GO:0006898receptor-mediated endocytosisTAS2251254 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS8093617 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HSPA1AFLJ54303 | FLJ54370 | FLJ54392 | FLJ54408 | FLJ75127 | HSP70-1 | HSP70-1A | HSP70I | HSP72 | HSPA1 | HSPA1Bheat shock 70kDa protein 1A-HPRD,BioGRID11785981 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_UP 13378All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP 175120All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_DN 12984All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_DN 11878All SZGR genes in this pathway
HOWLIN_PUBERTAL_MAMMARY_GLAND 6940All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP 4424All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP 8864All SZGR genes in this pathway
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN 7748All SZGR genes in this pathway
APPEL_IMATINIB_RESPONSE 3322All SZGR genes in this pathway
LIAN_LIPA_TARGETS_6M 7447All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_DN 3321All SZGR genes in this pathway
LIAN_LIPA_TARGETS_3M 5936All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_UP 222139All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_UP 15692All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_UP 8152All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
WORSCHECH_TUMOR_REJECTION_UP 5632All SZGR genes in this pathway
SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP 2512All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP 10767All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
CROONQUIST_NRAS_SIGNALING_UP 4124All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_MESENCHYMAL 216130All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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