Gene Page: ATP1A3

Summary
GeneID  478
Symbol  ATP1A3
Synonyms  DYT12|MGC13276|RDP
Description  ATPase, Na+/K+ transporting, alpha 3 polypeptide
See related  HGNC:801|MIM:182350|Ensembl:ENSG00000105409|HPRD:01666|
Locus tag  -
Gene type  protein-coding
Map location  19q13.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
IDH3A0.920.91
AC005277.10.910.91
NAP1L20.900.94
MOAP10.900.91
NSF0.900.90
MAP1A0.900.89
MAPK90.900.92
NDRG30.900.88
SNX100.890.92
CNTNAP10.890.90
Top 10 negatively co-expressed genes
BCL7C-0.55-0.60
NME4-0.52-0.60
RPL28-0.48-0.54
RPS19P3-0.48-0.53
HYAL2-0.48-0.46
RPL23A-0.47-0.47
SH3BP2-0.47-0.46
RPL18-0.47-0.50
RPS16P1-0.46-0.53
RPL37-0.46-0.56
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:0005524ATP bindingIEA-
GO:0005524ATP bindingNAS15260953 
GO:0005391sodium:potassium-exchanging ATPase activityIMP15260953 
GO:0016787hydrolase activityIEA-
GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesIEA-
GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismIEA-
GO:0015077monovalent inorganic cation transmembrane transporter activityIEA-
GO:0030955potassium ion bindingIEA-
GO:0031402sodium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0035235ionotropic glutamate receptor signaling pathwayIEAglutamate (GO term level: 8)-
GO:0008344adult locomotory behaviorIEA-
GO:0008542visual learningIEA-
GO:0008152metabolic processIEA-
GO:0007613memoryIEA-
GO:0006814sodium ion transportIEA-
GO:0006813potassium ion transportIEA-
GO:0042493response to drugIEA-
GO:0030317sperm motilityISS-
GO:0030641regulation of cellular pHISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA15260953 
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIDA15260953 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneNAS15260953 
GO:0005886plasma membraneIDA15260953 
GO:0005890sodium:potassium-exchanging ATPase complexIC15260953 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CARDIAC_MUSCLE_CONTRACTION 8051All SZGR genes in this pathway
KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION 4229All SZGR genes in this pathway
KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 2316All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES 3421All SZGR genes in this pathway
REACTOME_ION_CHANNEL_TRANSPORT 5542All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_DN 13797All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
SMITH_TERT_TARGETS_DN 8769All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN 4232All SZGR genes in this pathway
KUNINGER_IGF1_VS_PDGFB_TARGETS_DN 4628All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN 3225All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-185168174m8hsa-miR-185brainUGGAGAGAAAGGCAGUUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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