Gene Page: AVP
Summary ?
| GeneID | 551 |
| Symbol | AVP |
| Synonyms | ADH|ARVP|AVP-NPII|AVRP|VP |
| Description | arginine vasopressin |
| Reference | MIM:192340|HGNC:HGNC:894|Ensembl:ENSG00000101200|HPRD:01891|Vega:OTTHUMG00000031733 |
| Gene type | protein-coding |
| Map location | 20p13 |
| Pascal p-value | 0.393 |
| Fetal beta | 0.007 |
| Support | NEUROTROPHIN SIGNALING |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF831 | 0.39 | 0.28 |
| TMEM184B | 0.37 | 0.37 |
| AL645924.1 | 0.37 | 0.26 |
| RXRA | 0.36 | 0.40 |
| MINK1 | 0.35 | 0.31 |
| RBP3 | 0.35 | 0.28 |
| RHPN1 | 0.35 | 0.32 |
| HLA-DRB5 | 0.35 | 0.31 |
| FICD | 0.35 | 0.40 |
| ASB1 | 0.35 | 0.37 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FAM36A | -0.26 | -0.24 |
| C9orf46 | -0.24 | -0.24 |
| STMN1 | -0.24 | -0.23 |
| SNORA32 | -0.24 | -0.27 |
| RBMX2 | -0.24 | -0.24 |
| TIGD7 | -0.24 | -0.20 |
| FRG1 | -0.24 | -0.27 |
| ACAT1 | -0.23 | -0.21 |
| SNRPB2 | -0.23 | -0.23 |
| RBM34 | -0.23 | -0.26 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG VASOPRESSIN REGULATED WATER REABSORPTION | 44 | 30 | All SZGR 2.0 genes in this pathway |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | 36 | 27 | All SZGR 2.0 genes in this pathway |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 205 | 136 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY GPCR | 920 | 449 | All SZGR 2.0 genes in this pathway |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 108 | All SZGR 2.0 genes in this pathway |
| REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | 305 | 177 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES | 413 | 270 | All SZGR 2.0 genes in this pathway |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 184 | 116 | All SZGR 2.0 genes in this pathway |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 241 | 157 | All SZGR 2.0 genes in this pathway |
| REACTOME GPCR DOWNSTREAM SIGNALING | 805 | 368 | All SZGR 2.0 genes in this pathway |
| REACTOME G ALPHA S SIGNALLING EVENTS | 121 | 82 | All SZGR 2.0 genes in this pathway |
| REACTOME GPCR LIGAND BINDING | 408 | 246 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 31 | 16 | All SZGR 2.0 genes in this pathway |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 34 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 11 | 6 | All SZGR 2.0 genes in this pathway |
| REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | 44 | 30 | All SZGR 2.0 genes in this pathway |
| REACTOME CIRCADIAN CLOCK | 53 | 40 | All SZGR 2.0 genes in this pathway |
| BENPORATH MYC TARGETS WITH EBOX | 230 | 156 | All SZGR 2.0 genes in this pathway |
| UEDA CENTRAL CLOCK | 88 | 62 | All SZGR 2.0 genes in this pathway |
| LEE AGING NEOCORTEX UP | 89 | 59 | All SZGR 2.0 genes in this pathway |
| SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 | 419 | 273 | All SZGR 2.0 genes in this pathway |
| MCCABE BOUND BY HOXC6 | 469 | 239 | All SZGR 2.0 genes in this pathway |
| YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS WITH HCP H3K27ME3 | 102 | 76 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3K27ME3 | 590 | 403 | All SZGR 2.0 genes in this pathway |
| HOFFMAN CLOCK TARGETS DN | 10 | 6 | All SZGR 2.0 genes in this pathway |