Gene Page: BBS4

Summary
GeneID  585
Symbol  BBS4
Synonyms  -
Description  Bardet-Biedl syndrome 4
See related  HGNC:969|MIM:600374|Ensembl:ENSG00000140463|HPRD:08982|
Locus tag  -
Gene type  protein-coding
Map location  15q22.3-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003777microtubule motor activityIMP15107855 
GO:0005515protein bindingIPI15107855 
GO:0034452dynactin bindingIDA15107855 
GO:0043014alpha-tubulin bindingIDA17574030 
GO:0048487beta-tubulin bindingIDA17574030 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0035058sensory cilium biogenesisIEAneuron (GO term level: 10)-
GO:0016358dendrite developmentIEAneurite, dendrite (GO term level: 11)-
GO:0000226microtubule cytoskeleton organizationIEA-
GO:0001895retina homeostasisIEA-
GO:0001843neural tube closureIEA-
GO:0007286spermatid developmentIEA-
GO:0007608sensory perception of smellIEA-
GO:0033365protein localization in organelleISS-
GO:0033205cytokinesis during cell cycleIMP15107855 
GO:0034454microtubule anchoring at centrosomeIMP15107855 
GO:0030534adult behaviorIEA-
GO:0050896response to stimulusIEA-
GO:0050893sensory processingTAS14520415 
GO:0019216regulation of lipid metabolic processIEA-
GO:0051297centrosome organizationIMP15107855 
GO:0032465regulation of cytokinesisIMP15107855 
GO:0045724positive regulation of flagellum biogenesisIEA-
GO:0046548retinal rod cell developmentIEA-
GO:0045494photoreceptor cell maintenanceIEA-
GO:0051457maintenance of protein location in nucleusIGI15107855 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000242pericentriolar materialIDA15107855 
GO:0005814centrioleIDA15107855 
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
GO:0005932basal bodyIDA15107855 |18299575 
GO:0034464BBSomeIDA17574030 
GO:0034451centriolar satelliteIDA15107855 
GO:0031514motile secondary ciliumIDA18299575 
GO:0031513nonmotile primary ciliumIDA17574030 
GO:0060170cilium membraneIDA17574030 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DCTN1DAP-150 | DP-150 | HMN7B | P135dynactin 1 (p150, glued homolog, Drosophila)Affinity Capture-Western
Two-hybrid		BioGRID15107855 
PCM1PTC4pericentriolar material 1-HPRD,BioGRID15107855 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_UP 3622All SZGR genes in this pathway
NOUZOVA_TRETINOIN_AND_H4_ACETYLATION 14385All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_DN 10170All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
MATZUK_SPERMATOZOA 11477All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
KRIEG_KDM3A_TARGETS_NOT_HYPOXIA 208107All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway


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