Gene Page: CCL3
Summary ?
GeneID | 6348 |
Symbol | CCL3 |
Synonyms | G0S19-1|LD78ALPHA|MIP-1-alpha|MIP1A|SCYA3 |
Description | C-C motif chemokine ligand 3 |
Reference | MIM:182283|HGNC:HGNC:10627|Ensembl:ENSG00000277632|HPRD:01656|Vega:OTTHUMG00000188413 |
Gene type | protein-coding |
Map location | 17q12 |
Pascal p-value | 0.539 |
Fetal beta | -0.223 |
eGene | Myers' cis & trans |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs10491115 | chr17 | 33969406 | CCL3 | 6348 | 0.1 | cis | ||
rs3760325 | chr17 | 34037419 | CCL3 | 6348 | 0.08 | cis | ||
rs983619 | chr1 | 39047418 | CCL3 | 6348 | 0.12 | trans | ||
rs7545984 | chr1 | 45003892 | CCL3 | 6348 | 0.15 | trans | ||
rs7554123 | chr1 | 45004203 | CCL3 | 6348 | 0.15 | trans | ||
rs12059674 | chr1 | 57630277 | CCL3 | 6348 | 0.11 | trans | ||
rs17474410 | chr1 | 68267242 | CCL3 | 6348 | 0.18 | trans | ||
rs7511937 | 0 | CCL3 | 6348 | 0.06 | trans | |||
rs17689089 | chr1 | 77740105 | CCL3 | 6348 | 0 | trans | ||
rs17100231 | chr1 | 77761339 | CCL3 | 6348 | 0.06 | trans | ||
rs17100274 | chr1 | 77774412 | CCL3 | 6348 | 1.08E-4 | trans | ||
rs12034005 | chr1 | 79793034 | CCL3 | 6348 | 0.14 | trans | ||
rs17098656 | chr1 | 80098386 | CCL3 | 6348 | 0 | trans | ||
rs6664544 | chr1 | 92524192 | CCL3 | 6348 | 0.1 | trans | ||
rs12403481 | chr1 | 109503655 | CCL3 | 6348 | 0 | trans | ||
rs337294 | 0 | CCL3 | 6348 | 0.01 | trans | |||
rs17029293 | chr1 | 112567844 | CCL3 | 6348 | 8.653E-6 | trans | ||
rs12568798 | chr1 | 164355032 | CCL3 | 6348 | 0.07 | trans | ||
rs6701323 | chr1 | 178588280 | CCL3 | 6348 | 0.19 | trans | ||
rs16843112 | chr1 | 198420657 | CCL3 | 6348 | 0.15 | trans | ||
rs697455 | chr1 | 202512075 | CCL3 | 6348 | 0.08 | trans | ||
rs1796829 | chr1 | 239661818 | CCL3 | 6348 | 0.02 | trans | ||
rs12034521 | chr1 | 239717679 | CCL3 | 6348 | 0 | trans | ||
snp_a-1990354 | 0 | CCL3 | 6348 | 3.783E-5 | trans | |||
rs6432434 | chr2 | 14160930 | CCL3 | 6348 | 0.13 | trans | ||
rs12329305 | chr2 | 19552912 | CCL3 | 6348 | 0.07 | trans | ||
rs12611832 | chr2 | 31196248 | CCL3 | 6348 | 5.841E-5 | trans | ||
rs12614732 | chr2 | 31199913 | CCL3 | 6348 | 5.841E-5 | trans | ||
rs7560081 | chr2 | 62793238 | CCL3 | 6348 | 0.16 | trans | ||
rs17029079 | chr2 | 64736071 | CCL3 | 6348 | 0.07 | trans | ||
rs17038084 | chr2 | 85192280 | CCL3 | 6348 | 1.271E-5 | trans | ||
rs1840209 | chr2 | 125625401 | CCL3 | 6348 | 0.08 | trans | ||
rs6707117 | chr2 | 136855504 | CCL3 | 6348 | 1.201E-7 | trans | ||
rs10189091 | chr2 | 143471999 | CCL3 | 6348 | 0.01 | trans | ||
snp_a-2198363 | 0 | CCL3 | 6348 | 0.09 | trans | |||
rs707097 | chr2 | 155318814 | CCL3 | 6348 | 0.02 | trans | ||
rs16838911 | chr2 | 156087569 | CCL3 | 6348 | 8.507E-4 | trans | ||
rs7608942 | chr2 | 182820100 | CCL3 | 6348 | 0.05 | trans | ||
rs16829292 | chr2 | 233447622 | CCL3 | 6348 | 0.07 | trans | ||
rs16829401 | chr2 | 233538391 | CCL3 | 6348 | 0.07 | trans | ||
rs17040622 | chr3 | 4440673 | CCL3 | 6348 | 0.19 | trans | ||
rs17684934 | chr3 | 4443547 | CCL3 | 6348 | 0.01 | trans | ||
rs17040633 | chr3 | 4446836 | CCL3 | 6348 | 0.01 | trans | ||
rs17756483 | chr3 | 4451309 | CCL3 | 6348 | 0.01 | trans | ||
rs17685441 | chr3 | 4465165 | CCL3 | 6348 | 0.01 | trans | ||
rs3796213 | chr3 | 69157380 | CCL3 | 6348 | 0.14 | trans | ||
rs2875492 | chr3 | 86006209 | CCL3 | 6348 | 0.08 | trans | ||
rs16843128 | chr3 | 100713413 | CCL3 | 6348 | 0.08 | trans | ||
rs1381835 | chr3 | 110600595 | CCL3 | 6348 | 9.419E-4 | trans | ||
rs9288980 | chr3 | 112964991 | CCL3 | 6348 | 0.01 | trans | ||
rs3995908 | chr3 | 112998529 | CCL3 | 6348 | 0.01 | trans | ||
rs7652801 | chr3 | 113008605 | CCL3 | 6348 | 0.01 | trans | ||
rs7625829 | chr3 | 113103743 | CCL3 | 6348 | 0.01 | trans | ||
rs4419353 | chr3 | 113254936 | CCL3 | 6348 | 0.15 | trans | ||
rs17636599 | chr3 | 143028186 | CCL3 | 6348 | 0.01 | trans | ||
rs16839796 | chr4 | 7188348 | CCL3 | 6348 | 4.118E-4 | trans | ||
rs16885724 | chr4 | 31717283 | CCL3 | 6348 | 0.2 | trans | ||
rs11096966 | chr4 | 38961258 | CCL3 | 6348 | 0.12 | trans | ||
rs4469113 | chr4 | 41461062 | CCL3 | 6348 | 0.01 | trans | ||
rs6836259 | chr4 | 57173074 | CCL3 | 6348 | 0.08 | trans | ||
rs2643038 | chr4 | 62313218 | CCL3 | 6348 | 0.19 | trans | ||
rs6817626 | chr4 | 78005836 | CCL3 | 6348 | 0.17 | trans | ||
rs1604153 | chr4 | 78472744 | CCL3 | 6348 | 0.16 | trans | ||
rs1564462 | chr4 | 79910988 | CCL3 | 6348 | 0.03 | trans | ||
rs17005000 | chr4 | 81826551 | CCL3 | 6348 | 0.01 | trans | ||
rs10011751 | chr4 | 93984994 | CCL3 | 6348 | 0.03 | trans | ||
rs6881821 | chr5 | 8578465 | CCL3 | 6348 | 0.01 | trans | ||
rs1697073 | chr5 | 30907267 | CCL3 | 6348 | 0.09 | trans | ||
rs2115110 | chr5 | 38193428 | CCL3 | 6348 | 0.01 | trans | ||
rs16873956 | chr5 | 44312488 | CCL3 | 6348 | 0.1 | trans | ||
rs10040715 | chr5 | 57594207 | CCL3 | 6348 | 8.691E-8 | trans | ||
rs16894149 | chr5 | 61013724 | CCL3 | 6348 | 0.01 | trans | ||
snp_a-4217300 | 0 | CCL3 | 6348 | 5.64E-8 | trans | |||
rs163953 | chr5 | 92289536 | CCL3 | 6348 | 0.12 | trans | ||
rs17134275 | chr5 | 100634998 | CCL3 | 6348 | 0.15 | trans | ||
rs26604 | chr5 | 115792367 | CCL3 | 6348 | 0.07 | trans | ||
rs1350578 | chr5 | 116310282 | CCL3 | 6348 | 0.15 | trans | ||
rs2141482 | chr5 | 136760477 | CCL3 | 6348 | 0.01 | trans | ||
rs2189803 | chr5 | 137684661 | CCL3 | 6348 | 7.546E-5 | trans | ||
rs17063216 | chr5 | 163777647 | CCL3 | 6348 | 1.644E-4 | trans | ||
rs17063224 | chr5 | 163780687 | CCL3 | 6348 | 1.644E-4 | trans | ||
rs259913 | chr5 | 169370782 | CCL3 | 6348 | 0.01 | trans | ||
rs2116811 | chr5 | 171820051 | CCL3 | 6348 | 0.06 | trans | ||
rs258875 | chr5 | 173046554 | CCL3 | 6348 | 0.01 | trans | ||
rs16883859 | chr6 | 20474617 | CCL3 | 6348 | 0.05 | trans | ||
rs16883862 | chr6 | 20474766 | CCL3 | 6348 | 0.05 | trans | ||
rs10484635 | chr6 | 20538664 | CCL3 | 6348 | 0.19 | trans | ||
rs2057537 | chr6 | 35090278 | CCL3 | 6348 | 0.17 | trans | ||
rs195429 | chr6 | 37354434 | CCL3 | 6348 | 0.05 | trans | ||
rs12528414 | chr6 | 38404800 | CCL3 | 6348 | 0.08 | trans | ||
rs7771164 | chr6 | 40442772 | CCL3 | 6348 | 0.03 | trans | ||
rs4289676 | chr6 | 123999302 | CCL3 | 6348 | 0.15 | trans | ||
rs17055235 | chr6 | 128355263 | CCL3 | 6348 | 0.02 | trans | ||
rs12176346 | chr6 | 136732663 | CCL3 | 6348 | 0.02 | trans | ||
rs9402819 | chr6 | 136848169 | CCL3 | 6348 | 0.09 | trans | ||
rs9389400 | chr6 | 136854803 | CCL3 | 6348 | 0.09 | trans | ||
rs2237264 | chr6 | 136919977 | CCL3 | 6348 | 0.02 | trans | ||
rs17080121 | chr6 | 151009189 | CCL3 | 6348 | 0.06 | trans | ||
rs12529269 | chr6 | 153543829 | CCL3 | 6348 | 0.14 | trans | ||
rs10872699 | chr6 | 153544252 | CCL3 | 6348 | 0.01 | trans | ||
rs1321606 | chr6 | 153545278 | CCL3 | 6348 | 0.08 | trans | ||
rs10945911 | chr6 | 164047509 | CCL3 | 6348 | 0.01 | trans | ||
rs17136841 | chr7 | 16963043 | CCL3 | 6348 | 0.15 | trans | ||
rs12540348 | chr7 | 25802146 | CCL3 | 6348 | 0.04 | trans | ||
rs4719825 | chr7 | 25813917 | CCL3 | 6348 | 0 | trans | ||
rs6461881 | chr7 | 25837688 | CCL3 | 6348 | 0.05 | trans | ||
rs13239699 | chr7 | 26377619 | CCL3 | 6348 | 0.08 | trans | ||
rs12701006 | chr7 | 30147298 | CCL3 | 6348 | 1.785E-5 | trans | ||
rs17621151 | chr7 | 53572911 | CCL3 | 6348 | 8.16E-4 | trans | ||
rs10245449 | chr7 | 80935100 | CCL3 | 6348 | 0.18 | trans | ||
rs17166937 | chr7 | 95179901 | CCL3 | 6348 | 0.11 | trans | ||
rs2272618 | chr7 | 107871360 | CCL3 | 6348 | 0.11 | trans | ||
rs12669568 | chr7 | 107885942 | CCL3 | 6348 | 0.11 | trans | ||
rs7777322 | chr7 | 107886663 | CCL3 | 6348 | 0.11 | trans | ||
rs6958821 | chr7 | 153253566 | CCL3 | 6348 | 1.208E-5 | trans | ||
rs11779237 | chr8 | 1227664 | CCL3 | 6348 | 0.06 | trans | ||
rs1010895 | chr8 | 14580230 | CCL3 | 6348 | 0.19 | trans | ||
rs7001738 | chr8 | 26455799 | CCL3 | 6348 | 0.08 | trans | ||
rs16877914 | chr8 | 31196384 | CCL3 | 6348 | 0.15 | trans | ||
rs1457044 | chr8 | 59257567 | CCL3 | 6348 | 2.343E-4 | trans | ||
rs1457032 | chr8 | 59290536 | CCL3 | 6348 | 0.01 | trans | ||
rs2680903 | chr8 | 59512333 | CCL3 | 6348 | 0.13 | trans | ||
rs2634533 | chr8 | 59535621 | CCL3 | 6348 | 0.18 | trans | ||
rs7465259 | 0 | CCL3 | 6348 | 0 | trans | |||
rs10104622 | chr8 | 63333773 | CCL3 | 6348 | 0 | trans | ||
rs2218911 | chr8 | 63371015 | CCL3 | 6348 | 0 | trans | ||
rs1551199 | chr8 | 63388117 | CCL3 | 6348 | 0 | trans | ||
rs1593374 | chr8 | 64845850 | CCL3 | 6348 | 0 | trans | ||
rs1733950 | chr8 | 90062516 | CCL3 | 6348 | 3.125E-9 | trans | ||
rs1240028 | chr8 | 90093357 | CCL3 | 6348 | 0 | trans | ||
rs1240087 | chr8 | 90113945 | CCL3 | 6348 | 0.01 | trans | ||
rs318307 | chr8 | 90185459 | CCL3 | 6348 | 0 | trans | ||
rs1483373 | chr8 | 90186442 | CCL3 | 6348 | 0.07 | trans | ||
rs11776005 | chr8 | 90187416 | CCL3 | 6348 | 0.02 | trans | ||
rs1159499 | chr8 | 90196948 | CCL3 | 6348 | 0.07 | trans | ||
rs1355060 | chr8 | 118717710 | CCL3 | 6348 | 0.14 | trans | ||
rs2280828 | chr8 | 118762435 | CCL3 | 6348 | 0.11 | trans | ||
rs2514602 | chr8 | 119650549 | CCL3 | 6348 | 0.13 | trans | ||
rs17683401 | chr8 | 119671834 | CCL3 | 6348 | 0.05 | trans | ||
rs4976941 | chr8 | 142744439 | CCL3 | 6348 | 0.01 | trans | ||
rs9298651 | chr9 | 10076275 | CCL3 | 6348 | 0.01 | trans | ||
rs16931013 | chr9 | 10076859 | CCL3 | 6348 | 0.01 | trans | ||
rs16931018 | chr9 | 10077048 | CCL3 | 6348 | 0.01 | trans | ||
rs1467547 | chr9 | 17630726 | CCL3 | 6348 | 0.06 | trans | ||
rs2210327 | chr9 | 18109234 | CCL3 | 6348 | 0.04 | trans | ||
rs6476383 | chr9 | 32865568 | CCL3 | 6348 | 0.03 | trans | ||
rs11143622 | chr9 | 71370050 | CCL3 | 6348 | 0.01 | trans | ||
rs11143868 | chr9 | 71437411 | CCL3 | 6348 | 0.12 | trans | ||
rs11143995 | chr9 | 71462852 | CCL3 | 6348 | 0.12 | trans | ||
rs11144031 | chr9 | 71477107 | CCL3 | 6348 | 0.12 | trans | ||
rs11791891 | chr9 | 87512411 | CCL3 | 6348 | 0.13 | trans | ||
rs2165893 | chr9 | 87531423 | CCL3 | 6348 | 0.11 | trans | ||
rs3780642 | chr9 | 87553144 | CCL3 | 6348 | 2.357E-4 | trans | ||
rs10992752 | chr9 | 96240578 | CCL3 | 6348 | 0.11 | trans | ||
rs2807706 | chr9 | 121744331 | CCL3 | 6348 | 0.02 | trans | ||
rs2818297 | chr9 | 121757015 | CCL3 | 6348 | 0.1 | trans | ||
rs10739527 | chr9 | 121772512 | CCL3 | 6348 | 0.17 | trans | ||
rs11103132 | chr9 | 138575901 | CCL3 | 6348 | 0.12 | trans | ||
rs11014370 | chr10 | 25352798 | CCL3 | 6348 | 0.06 | trans | ||
rs17432714 | chr10 | 43526022 | CCL3 | 6348 | 0.1 | trans | ||
rs2853836 | chr10 | 48431948 | CCL3 | 6348 | 0.19 | trans | ||
rs3104871 | chr10 | 57878502 | CCL3 | 6348 | 0 | trans | ||
rs901309 | chr10 | 72571899 | CCL3 | 6348 | 0.14 | trans | ||
rs17271314 | chr10 | 86662514 | CCL3 | 6348 | 0.02 | trans | ||
rs485305 | chr10 | 116048044 | CCL3 | 6348 | 6.179E-4 | trans | ||
rs4750827 | chr10 | 132547183 | CCL3 | 6348 | 0.05 | trans | ||
rs4750829 | chr10 | 132547260 | CCL3 | 6348 | 0.08 | trans | ||
rs11021900 | chr11 | 11548236 | CCL3 | 6348 | 0.18 | trans | ||
rs862785 | chr11 | 20175604 | CCL3 | 6348 | 0.03 | trans | ||
rs16911034 | chr11 | 23302320 | CCL3 | 6348 | 0.09 | trans | ||
rs11020043 | chr11 | 92470587 | CCL3 | 6348 | 0.1 | trans | ||
rs1789300 | chr11 | 95463631 | CCL3 | 6348 | 0.01 | trans | ||
rs1727152 | chr11 | 95467435 | CCL3 | 6348 | 0.04 | trans | ||
rs1255149 | chr11 | 95484493 | CCL3 | 6348 | 0.01 | trans | ||
rs3748251 | chr11 | 95519156 | CCL3 | 6348 | 0 | trans | ||
rs16922543 | chr11 | 95526116 | CCL3 | 6348 | 0 | trans | ||
rs16922622 | chr11 | 95567387 | CCL3 | 6348 | 0 | trans | ||
rs3181323 | chr11 | 104878386 | CCL3 | 6348 | 0.02 | trans | ||
rs11219092 | chr11 | 123130750 | CCL3 | 6348 | 0.01 | trans | ||
rs374484 | chr12 | 27627159 | CCL3 | 6348 | 0.08 | trans | ||
rs10783318 | chr12 | 39070575 | CCL3 | 6348 | 0.05 | trans | ||
rs180424 | chr12 | 47171757 | CCL3 | 6348 | 0.13 | trans | ||
rs17097455 | chr12 | 47398974 | CCL3 | 6348 | 0.12 | trans | ||
rs17097566 | chr12 | 47460199 | CCL3 | 6348 | 0.12 | trans | ||
rs8490 | chr12 | 51453904 | CCL3 | 6348 | 6.239E-5 | trans | ||
rs1344796 | chr12 | 76397104 | CCL3 | 6348 | 0.08 | trans | ||
rs10850201 | chr12 | 109903061 | CCL3 | 6348 | 0.15 | trans | ||
rs11833075 | chr12 | 122114592 | CCL3 | 6348 | 0 | trans | ||
rs1041050 | chr13 | 26585121 | CCL3 | 6348 | 0.02 | trans | ||
rs2408301 | chr13 | 51808915 | CCL3 | 6348 | 2.113E-4 | trans | ||
rs7982110 | chr13 | 59723428 | CCL3 | 6348 | 0.01 | trans | ||
rs7330331 | chr13 | 67403122 | CCL3 | 6348 | 0.02 | trans | ||
rs17088392 | chr13 | 72257235 | CCL3 | 6348 | 0 | trans | ||
rs7327697 | chr13 | 83227456 | CCL3 | 6348 | 0.01 | trans | ||
rs17667894 | chr13 | 92014308 | CCL3 | 6348 | 0.1 | trans | ||
rs17257605 | chr14 | 25405534 | CCL3 | 6348 | 0.04 | trans | ||
rs7156088 | chr14 | 27821865 | CCL3 | 6348 | 0.04 | trans | ||
rs17106703 | chr14 | 37851979 | CCL3 | 6348 | 0.08 | trans | ||
rs8022005 | chr14 | 61345380 | CCL3 | 6348 | 0.07 | trans | ||
rs10148418 | chr14 | 67003872 | CCL3 | 6348 | 0.16 | trans | ||
rs4905035 | chr14 | 93489262 | CCL3 | 6348 | 0.08 | trans | ||
rs941539 | chr14 | 93561214 | CCL3 | 6348 | 3.076E-4 | trans | ||
rs1885073 | chr14 | 104357181 | CCL3 | 6348 | 1.2E-5 | trans | ||
rs16973929 | chr15 | 47395709 | CCL3 | 6348 | 0.11 | trans | ||
rs8039808 | chr15 | 49939845 | CCL3 | 6348 | 0.18 | trans | ||
rs2414703 | chr15 | 61904602 | CCL3 | 6348 | 0.15 | trans | ||
rs289171 | chr15 | 62576053 | CCL3 | 6348 | 0.05 | trans | ||
rs289161 | chr15 | 62589888 | CCL3 | 6348 | 0.13 | trans | ||
rs2249982 | chr15 | 70236349 | CCL3 | 6348 | 3.615E-4 | trans | ||
rs939043 | chr15 | 70236428 | CCL3 | 6348 | 3.336E-5 | trans | ||
rs11858762 | chr15 | 81386594 | CCL3 | 6348 | 0.11 | trans | ||
rs9635390 | chr15 | 90809632 | CCL3 | 6348 | 0.02 | trans | ||
rs7174562 | chr15 | 93811530 | CCL3 | 6348 | 0.13 | trans | ||
rs8047151 | chr16 | 17209696 | CCL3 | 6348 | 5.239E-5 | trans | ||
rs4271578 | chr16 | 17213886 | CCL3 | 6348 | 4.583E-4 | trans | ||
rs7200513 | chr16 | 17219474 | CCL3 | 6348 | 0.13 | trans | ||
rs3829495 | chr16 | 17221986 | CCL3 | 6348 | 0.01 | trans | ||
rs7193763 | chr16 | 17225534 | CCL3 | 6348 | 0 | trans | ||
rs11861635 | chr16 | 82543377 | CCL3 | 6348 | 0.01 | trans | ||
rs1867231 | chr17 | 13678834 | CCL3 | 6348 | 0.16 | trans | ||
rs757075 | chr17 | 31372017 | CCL3 | 6348 | 0.17 | trans | ||
rs7219986 | chr17 | 53263206 | CCL3 | 6348 | 0.08 | trans | ||
rs17817797 | chr17 | 53332496 | CCL3 | 6348 | 5.712E-4 | trans | ||
rs16951770 | chr18 | 7444826 | CCL3 | 6348 | 0.1 | trans | ||
rs16951384 | chr18 | 47527116 | CCL3 | 6348 | 0.09 | trans | ||
rs8095378 | chr18 | 49283781 | CCL3 | 6348 | 0.05 | trans | ||
rs17074993 | chr18 | 63260128 | CCL3 | 6348 | 0.12 | trans | ||
snp_a-1821751 | 0 | CCL3 | 6348 | 0.01 | trans | |||
rs1942464 | chr18 | 70509877 | CCL3 | 6348 | 0.13 | trans | ||
rs17056922 | chr18 | 73086804 | CCL3 | 6348 | 0.2 | trans | ||
rs1540047 | chr18 | 75047028 | CCL3 | 6348 | 0 | trans | ||
rs2850845 | chr18 | 75048150 | CCL3 | 6348 | 0.02 | trans | ||
rs2850843 | chr18 | 75048905 | CCL3 | 6348 | 0 | trans | ||
rs1540051 | chr18 | 75049934 | CCL3 | 6348 | 0 | trans | ||
rs6603096 | chr19 | 7415722 | CCL3 | 6348 | 0.15 | trans | ||
rs16980096 | chr19 | 15000921 | CCL3 | 6348 | 0.18 | trans | ||
snp_a-2138575 | 0 | CCL3 | 6348 | 0.04 | trans | |||
rs234363 | chr19 | 40474607 | CCL3 | 6348 | 0.19 | trans | ||
rs6417634 | chr20 | 6408617 | CCL3 | 6348 | 0.2 | trans | ||
rs16997215 | chr20 | 16101890 | CCL3 | 6348 | 0.04 | trans | ||
rs6026122 | chr20 | 56769083 | CCL3 | 6348 | 0.1 | trans | ||
rs6015452 | chr20 | 57782312 | CCL3 | 6348 | 0.16 | trans | ||
rs6124034 | chr20 | 59517206 | CCL3 | 6348 | 0.11 | trans | ||
rs6124036 | chr20 | 59517478 | CCL3 | 6348 | 0.11 | trans | ||
rs4812237 | chr20 | 59518040 | CCL3 | 6348 | 0.03 | trans | ||
rs6586271 | chr21 | 44362641 | CCL3 | 6348 | 0.1 | trans | ||
rs134028 | chr22 | 28048448 | CCL3 | 6348 | 0.01 | trans | ||
rs5762317 | chr22 | 28094988 | CCL3 | 6348 | 0.07 | trans | ||
rs5768165 | chr22 | 48318197 | CCL3 | 6348 | 0.01 | trans | ||
rs5768168 | chr22 | 48319334 | CCL3 | 6348 | 0.01 | trans | ||
rs5768173 | chr22 | 48321475 | CCL3 | 6348 | 0.01 | trans | ||
rs6567620 | 0 | CCL3 | 6348 | 0.14 | trans | |||
rs12006821 | chrX | 50424687 | CCL3 | 6348 | 0.13 | trans | ||
rs16992781 | chrX | 146460376 | CCL3 | 6348 | 0.05 | trans | ||
rs4824295 | chrX | 146496881 | CCL3 | 6348 | 0.02 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0004871 | signal transducer activity | TAS | 10857861 | |
GO:0008009 | chemokine activity | TAS | 10660125 | |
GO:0042056 | chemoattractant activity | IDA | 15001559 | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0007186 | G-protein coupled receptor protein signaling pathway | TAS | 10734056 | |
GO:0007267 | cell-cell signaling | TAS | 10679098 | |
GO:0007010 | cytoskeleton organization | TAS | 10072545 | |
GO:0007165 | signal transduction | TAS | 10706735 | |
GO:0006955 | immune response | IEA | - | |
GO:0006954 | inflammatory response | TAS | 10679098 | |
GO:0006935 | chemotaxis | TAS | 10679098 | |
GO:0006928 | cell motion | TAS | 10660125 | |
GO:0006887 | exocytosis | TAS | 10734056 | |
GO:0006874 | cellular calcium ion homeostasis | TAS | 10734056 | |
GO:0045069 | regulation of viral genome replication | TAS | 10841574 | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0005576 | extracellular region | IEA | - | |
GO:0005615 | extracellular space | IEA | - | |
GO:0005625 | soluble fraction | TAS | 10706735 |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
BCL6 | BCL5 | BCL6A | LAZ3 | ZBTB27 | ZNF51 | B-cell CLL/lymphoma 6 | BCL6 interacts with the CCL3 promoter region. | BIND | 15531890 |
CCBP2 | CCR10 | CCR9 | CMKBR9 | D6 | MGC126678 | MGC138250 | hD6 | chemokine binding protein 2 | - | HPRD | 9405404 |
CCL3 | G0S19-1 | LD78ALPHA | MIP-1-alpha | MIP1A | SCYA3 | chemokine (C-C motif) ligand 3 | - | HPRD | 8460127 |
CCL3 | G0S19-1 | LD78ALPHA | MIP-1-alpha | MIP1A | SCYA3 | chemokine (C-C motif) ligand 3 | Reconstituted Complex | BioGRID | 8077676 |
CCL4 | ACT2 | AT744.1 | G-26 | LAG1 | MGC104418 | MGC126025 | MGC126026 | MIP-1-beta | MIP1B | MIP1B1 | SCYA2 | SCYA4 | chemokine (C-C motif) ligand 4 | - | HPRD,BioGRID | 11278300 |
CCR1 | CD191 | CKR-1 | CKR1 | CMKBR1 | HM145 | MIP1aR | SCYAR1 | chemokine (C-C motif) receptor 1 | - | HPRD | 10202040|10660125 |
CCR4 | CC-CKR-4 | CD194 | CKR4 | CMKBR4 | ChemR13 | HGCN:14099 | K5-5 | MGC88293 | chemokine (C-C motif) receptor 4 | - | HPRD,BioGRID | 8573157 |
CCR5 | CC-CKR-5 | CCCKR5 | CD195 | CKR-5 | CKR5 | CMKBR5 | chemokine (C-C motif) receptor 5 | - | HPRD,BioGRID | 11700073 |
NCOR1 | KIAA1047 | MGC104216 | N-CoR | TRAC1 | hCIT529I10 | hN-CoR | nuclear receptor co-repressor 1 | NcoR interacts with the CCL3 promoter region. | BIND | 15531890 |
NCOR2 | CTG26 | SMRT | SMRTE | SMRTE-tau | TNRC14 | TRAC-1 | TRAC1 | nuclear receptor co-repressor 2 | SMRT interacts with the CCL3 promoter region. | BIND | 15531890 |
SRGN | FLJ12930 | MGC9289 | PPG | PRG | PRG1 | serglycin | - | HPRD | 8613703 |
TGFB1 | CED | DPD1 | TGFB | TGFbeta | transforming growth factor, beta 1 | - | HPRD | 8568261 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | 267 | 161 | All SZGR 2.0 genes in this pathway |
KEGG CHEMOKINE SIGNALING PATHWAY | 190 | 128 | All SZGR 2.0 genes in this pathway |
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY | 102 | 88 | All SZGR 2.0 genes in this pathway |
BIOCARTA ERYTH PATHWAY | 15 | 11 | All SZGR 2.0 genes in this pathway |
BIOCARTA NKT PATHWAY | 29 | 21 | All SZGR 2.0 genes in this pathway |
PID IL12 2PATHWAY | 63 | 54 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY GPCR | 920 | 449 | All SZGR 2.0 genes in this pathway |
REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 108 | All SZGR 2.0 genes in this pathway |
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | 305 | 177 | All SZGR 2.0 genes in this pathway |
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 57 | 27 | All SZGR 2.0 genes in this pathway |
REACTOME GPCR LIGAND BINDING | 408 | 246 | All SZGR 2.0 genes in this pathway |
MARKEY RB1 CHRONIC LOF DN | 118 | 78 | All SZGR 2.0 genes in this pathway |
MARKEY RB1 ACUTE LOF UP | 215 | 137 | All SZGR 2.0 genes in this pathway |
DEBOSSCHER NFKB TARGETS REPRESSED BY GLUCOCORTICOIDS | 24 | 18 | All SZGR 2.0 genes in this pathway |
DIRMEIER LMP1 RESPONSE EARLY | 66 | 48 | All SZGR 2.0 genes in this pathway |
FUNG IL2 SIGNALING 2 | 12 | 8 | All SZGR 2.0 genes in this pathway |
FUNG IL2 TARGETS WITH STAT5 BINDING SITES T1 | 9 | 7 | All SZGR 2.0 genes in this pathway |
TSAI RESPONSE TO IONIZING RADIATION | 149 | 101 | All SZGR 2.0 genes in this pathway |
PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
SHIN B CELL LYMPHOMA CLUSTER 1 | 13 | 11 | All SZGR 2.0 genes in this pathway |
KAUFFMANN DNA REPLICATION GENES | 147 | 87 | All SZGR 2.0 genes in this pathway |
NIKOLSKY BREAST CANCER 17Q11 Q21 AMPLICON | 133 | 78 | All SZGR 2.0 genes in this pathway |
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS | 882 | 572 | All SZGR 2.0 genes in this pathway |
MAGRANGEAS MULTIPLE MYELOMA IGLL VS IGLK UP | 42 | 24 | All SZGR 2.0 genes in this pathway |
NAKAJIMA EOSINOPHIL | 30 | 20 | All SZGR 2.0 genes in this pathway |
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN | 85 | 67 | All SZGR 2.0 genes in this pathway |
PARK HSC MARKERS | 44 | 31 | All SZGR 2.0 genes in this pathway |
NEMETH INFLAMMATORY RESPONSE LPS UP | 88 | 64 | All SZGR 2.0 genes in this pathway |
THEILGAARD NEUTROPHIL AT SKIN WOUND UP | 77 | 52 | All SZGR 2.0 genes in this pathway |
BASSO CD40 SIGNALING UP | 101 | 76 | All SZGR 2.0 genes in this pathway |
BRUNO HEMATOPOIESIS | 66 | 48 | All SZGR 2.0 genes in this pathway |
BAELDE DIABETIC NEPHROPATHY UP | 86 | 48 | All SZGR 2.0 genes in this pathway |
KEEN RESPONSE TO ROSIGLITAZONE DN | 106 | 68 | All SZGR 2.0 genes in this pathway |
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN | 51 | 32 | All SZGR 2.0 genes in this pathway |
SAFFORD T LYMPHOCYTE ANERGY | 87 | 54 | All SZGR 2.0 genes in this pathway |
STEARMAN LUNG CANCER EARLY VS LATE DN | 61 | 39 | All SZGR 2.0 genes in this pathway |
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN | 154 | 101 | All SZGR 2.0 genes in this pathway |
MARZEC IL2 SIGNALING UP | 115 | 80 | All SZGR 2.0 genes in this pathway |
GAURNIER PSMD4 TARGETS | 73 | 55 | All SZGR 2.0 genes in this pathway |
AUJLA IL22 AND IL17A SIGNALING | 11 | 5 | All SZGR 2.0 genes in this pathway |
QI PLASMACYTOMA UP | 259 | 185 | All SZGR 2.0 genes in this pathway |
CROMER TUMORIGENESIS UP | 63 | 36 | All SZGR 2.0 genes in this pathway |
WANG TUMOR INVASIVENESS DN | 210 | 128 | All SZGR 2.0 genes in this pathway |
SEKI INFLAMMATORY RESPONSE LPS UP | 77 | 56 | All SZGR 2.0 genes in this pathway |
CHAUHAN RESPONSE TO METHOXYESTRADIOL DN | 102 | 65 | All SZGR 2.0 genes in this pathway |
GOLDRATH ANTIGEN RESPONSE | 346 | 192 | All SZGR 2.0 genes in this pathway |
LINDSTEDT DENDRITIC CELL MATURATION A | 67 | 52 | All SZGR 2.0 genes in this pathway |
YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
SHAFFER IRF4 TARGETS IN MYELOMA VS MATURE B LYMPHOCYTE | 101 | 76 | All SZGR 2.0 genes in this pathway |
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE | 67 | 51 | All SZGR 2.0 genes in this pathway |
SHAFFER IRF4 TARGETS IN ACTIVATED B LYMPHOCYTE | 81 | 66 | All SZGR 2.0 genes in this pathway |
CROONQUIST STROMAL STIMULATION UP | 60 | 42 | All SZGR 2.0 genes in this pathway |
CROONQUIST NRAS SIGNALING UP | 41 | 24 | All SZGR 2.0 genes in this pathway |
KUROZUMI RESPONSE TO ONCOCYTIC VIRUS | 44 | 30 | All SZGR 2.0 genes in this pathway |
HOSHIDA LIVER CANCER SUBCLASS S1 | 237 | 159 | All SZGR 2.0 genes in this pathway |
WONG ADULT TISSUE STEM MODULE | 721 | 492 | All SZGR 2.0 genes in this pathway |
LI INDUCED T TO NATURAL KILLER UP | 307 | 182 | All SZGR 2.0 genes in this pathway |
MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |
WIERENGA STAT5A TARGETS UP | 217 | 131 | All SZGR 2.0 genes in this pathway |
WIERENGA STAT5A TARGETS GROUP2 | 60 | 38 | All SZGR 2.0 genes in this pathway |
JUBAN TARGETS OF SPI1 AND FLI1 DN | 92 | 60 | All SZGR 2.0 genes in this pathway |
ALTEMEIER RESPONSE TO LPS WITH MECHANICAL VENTILATION | 128 | 81 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |
NABA SECRETED FACTORS | 344 | 197 | All SZGR 2.0 genes in this pathway |
NABA MATRISOME ASSOCIATED | 753 | 411 | All SZGR 2.0 genes in this pathway |
NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |