Gene Page: SST

Summary
GeneID  6750
Symbol  SST
Synonyms  SMST
Description  somatostatin
See related  HGNC:11329|MIM:182450|Ensembl:ENSG00000157005|HPRD:08920|
Locus tag  -
Gene type  protein-coding
Map location  3q28
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRC10.980.74
BUB10.970.59
CCNB20.970.55
TPX20.970.73
MELK0.970.62
EXO10.970.70
KIF4A0.970.69
NUSAP10.970.60
BUB1B0.970.64
KIF230.970.69
Top 10 negatively co-expressed genes
AF347015.31-0.38-0.61
MT-CO2-0.38-0.62
AF347015.33-0.38-0.61
AF347015.27-0.37-0.58
HLA-F-0.37-0.51
MT-CYB-0.37-0.61
IFI27-0.36-0.59
AF347015.8-0.36-0.61
PTH1R-0.36-0.50
C5orf53-0.36-0.43
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS9886848 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionTASneuron, Synap, Neurotransmitter (GO term level: 6)9437026 
GO:0007186G-protein coupled receptor protein signaling pathwayTAS8405411 
GO:0008285negative regulation of cell proliferationTAS9886848 
GO:0008628induction of apoptosis by hormonesTAS8961277 
GO:0007586digestionTAS6145156 
GO:0007584response to nutrientTAS6145156 
GO:0030334regulation of cell migrationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS9437026 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SSTR1SRIF-2somatostatin receptor 1-HPRD1346068 
SSTR2-somatostatin receptor 2-HPRD1346068 
SSTR3-somatostatin receptor 3-HPRD,BioGRID1337145 
SSTR4-somatostatin receptor 4-HPRD8100352 
SSTR5-somatostatin receptor 5-HPRD7908405 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP 12973All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN 13870All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_UP 10169All SZGR genes in this pathway
JIANG_AGING_HYPOTHALAMUS_UP 4731All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP 3624All SZGR genes in this pathway
IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN 10868All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED 8050All SZGR genes in this pathway
MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED 6331All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_EARLY_UP 6644All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
ROLEF_GLIS3_TARGETS 3729All SZGR genes in this pathway


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