Gene Page: TMEM50B
Summary ?
| GeneID | 757 |
| Symbol | TMEM50B |
| Synonyms | C21orf4|HCVP7TP3 |
| Description | transmembrane protein 50B |
| Reference | HGNC:HGNC:1280|Ensembl:ENSG00000142188|HPRD:10747|Vega:OTTHUMG00000065286 |
| Gene type | protein-coding |
| Map location | 21q22.11 |
| Pascal p-value | 0.005 |
| Fetal beta | 0.027 |
| DMG | 1 (# studies) |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:vanEijk_2014 | Genome-wide DNA methylation analysis | This dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg17356733 | 21 | 34774627 | TMEM50B | 0.003 | 2.944 | DMG:vanEijk_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs13050246 | 21 | 34841869 | TMEM50B | ENSG00000142188.12 | 1.429E-6 | 0.03 | 10449 | gtex_brain_ba24 |
| rs78293890 | 21 | 34859401 | TMEM50B | ENSG00000142188.12 | 2.59E-6 | 0.03 | -7083 | gtex_brain_ba24 |
| rs9808685 | 21 | 34785672 | TMEM50B | ENSG00000142188.12 | 3.062E-6 | 0 | 66646 | gtex_brain_putamen_basal |
| rs2834210 | 21 | 34786574 | TMEM50B | ENSG00000142188.12 | 3.062E-6 | 0 | 65744 | gtex_brain_putamen_basal |
| rs7283850 | 21 | 34789549 | TMEM50B | ENSG00000142188.12 | 1.16E-7 | 0 | 62769 | gtex_brain_putamen_basal |
| rs7277808 | 21 | 34789695 | TMEM50B | ENSG00000142188.12 | 3.048E-6 | 0 | 62623 | gtex_brain_putamen_basal |
| rs2834214 | 21 | 34793706 | TMEM50B | ENSG00000142188.12 | 3.052E-6 | 0 | 58612 | gtex_brain_putamen_basal |
| rs71326949 | 21 | 34794982 | TMEM50B | ENSG00000142188.12 | 2.44E-7 | 0 | 57336 | gtex_brain_putamen_basal |
| rs17885944 | 21 | 34796199 | TMEM50B | ENSG00000142188.12 | 9.381E-8 | 0 | 56119 | gtex_brain_putamen_basal |
| rs2834215 | 21 | 34796886 | TMEM50B | ENSG00000142188.12 | 3.026E-6 | 0 | 55432 | gtex_brain_putamen_basal |
| rs17882848 | 21 | 34797183 | TMEM50B | ENSG00000142188.12 | 2.243E-6 | 0 | 55135 | gtex_brain_putamen_basal |
| rs11910627 | 21 | 34799350 | TMEM50B | ENSG00000142188.12 | 1.164E-7 | 0 | 52968 | gtex_brain_putamen_basal |
| rs139258193 | 21 | 34800146 | TMEM50B | ENSG00000142188.12 | 2.245E-8 | 0 | 52172 | gtex_brain_putamen_basal |
| rs67816861 | 21 | 34800150 | TMEM50B | ENSG00000142188.12 | 1.036E-6 | 0 | 52168 | gtex_brain_putamen_basal |
| rs8130924 | 21 | 34800872 | TMEM50B | ENSG00000142188.12 | 1.132E-7 | 0 | 51446 | gtex_brain_putamen_basal |
| rs8132006 | 21 | 34802841 | TMEM50B | ENSG00000142188.12 | 1.053E-7 | 0 | 49477 | gtex_brain_putamen_basal |
| rs8132535 | 21 | 34802946 | TMEM50B | ENSG00000142188.12 | 3.957E-8 | 0 | 49372 | gtex_brain_putamen_basal |
| rs1532 | 21 | 34804966 | TMEM50B | ENSG00000142188.12 | 1.046E-7 | 0 | 47352 | gtex_brain_putamen_basal |
| rs17882822 | 21 | 34806091 | TMEM50B | ENSG00000142188.12 | 1.618E-8 | 0 | 46227 | gtex_brain_putamen_basal |
| rs2284554 | 21 | 34806218 | TMEM50B | ENSG00000142188.12 | 1.618E-8 | 0 | 46100 | gtex_brain_putamen_basal |
| rs2284555 | 21 | 34806288 | TMEM50B | ENSG00000142188.12 | 1.622E-8 | 0 | 46030 | gtex_brain_putamen_basal |
| rs2284556 | 21 | 34806305 | TMEM50B | ENSG00000142188.12 | 1.384E-8 | 0 | 46013 | gtex_brain_putamen_basal |
| rs2409493 | 21 | 34808289 | TMEM50B | ENSG00000142188.12 | 1.955E-8 | 0 | 44029 | gtex_brain_putamen_basal |
| rs2409494 | 21 | 34808408 | TMEM50B | ENSG00000142188.12 | 2.024E-8 | 0 | 43910 | gtex_brain_putamen_basal |
| rs2040120 | 21 | 34809049 | TMEM50B | ENSG00000142188.12 | 4.139E-8 | 0 | 43269 | gtex_brain_putamen_basal |
| rs1059293 | 21 | 34809693 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 42625 | gtex_brain_putamen_basal |
| rs8131980 | 21 | 34810007 | TMEM50B | ENSG00000142188.12 | 1.245E-7 | 0 | 42311 | gtex_brain_putamen_basal |
| rs4816452 | 21 | 34810330 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 41988 | gtex_brain_putamen_basal |
| rs4816453 | 21 | 34811357 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 40961 | gtex_brain_putamen_basal |
| rs6517171 | 21 | 34811711 | TMEM50B | ENSG00000142188.12 | 9.491E-8 | 0 | 40607 | gtex_brain_putamen_basal |
| rs6517172 | 21 | 34811835 | TMEM50B | ENSG00000142188.12 | 5.619E-8 | 0 | 40483 | gtex_brain_putamen_basal |
| rs4817567 | 21 | 34813316 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 39002 | gtex_brain_putamen_basal |
| rs4817568 | 21 | 34813400 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 38918 | gtex_brain_putamen_basal |
| rs6517173 | 21 | 34813562 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 38756 | gtex_brain_putamen_basal |
| rs71702114 | 21 | 34814327 | TMEM50B | ENSG00000142188.12 | 2.048E-8 | 0 | 37991 | gtex_brain_putamen_basal |
| rs1972256 | 21 | 34815111 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 37207 | gtex_brain_putamen_basal |
| rs4816455 | 21 | 34815794 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 36524 | gtex_brain_putamen_basal |
| rs7276112 | 21 | 34816479 | TMEM50B | ENSG00000142188.12 | 3.422E-8 | 0 | 35839 | gtex_brain_putamen_basal |
| rs9981203 | 21 | 34816988 | TMEM50B | ENSG00000142188.12 | 1.232E-7 | 0 | 35330 | gtex_brain_putamen_basal |
| rs68082076 | 21 | 34818296 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 34022 | gtex_brain_putamen_basal |
| rs9976619 | 21 | 34818692 | TMEM50B | ENSG00000142188.12 | 1.35E-7 | 0 | 33626 | gtex_brain_putamen_basal |
| rs9976414 | 21 | 34819131 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 33187 | gtex_brain_putamen_basal |
| rs9976356 | 21 | 34819201 | TMEM50B | ENSG00000142188.12 | 9.064E-8 | 0 | 33117 | gtex_brain_putamen_basal |
| rs7282496 | 21 | 34819582 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 32736 | gtex_brain_putamen_basal |
| rs11088253 | 21 | 34820317 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 32001 | gtex_brain_putamen_basal |
| rs8133486 | 21 | 34820803 | TMEM50B | ENSG00000142188.12 | 1.037E-7 | 0 | 31515 | gtex_brain_putamen_basal |
| rs8134200 | 21 | 34821131 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 31187 | gtex_brain_putamen_basal |
| rs2834216 | 21 | 34821372 | TMEM50B | ENSG00000142188.12 | 4.897E-8 | 0 | 30946 | gtex_brain_putamen_basal |
| rs1044218 | 21 | 34821570 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 30748 | gtex_brain_putamen_basal |
| rs1044213 | 21 | 34821691 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 30627 | gtex_brain_putamen_basal |
| rs2834217 | 21 | 34822150 | TMEM50B | ENSG00000142188.12 | 1.121E-8 | 0 | 30168 | gtex_brain_putamen_basal |
| rs2834218 | 21 | 34822452 | TMEM50B | ENSG00000142188.12 | 4.897E-8 | 0 | 29866 | gtex_brain_putamen_basal |
| rs71322211 | 21 | 34822493 | TMEM50B | ENSG00000142188.12 | 4.897E-8 | 0 | 29825 | gtex_brain_putamen_basal |
| rs60665114 | 21 | 34822508 | TMEM50B | ENSG00000142188.12 | 8.831E-8 | 0 | 29810 | gtex_brain_putamen_basal |
| rs11088254 | 21 | 34822582 | TMEM50B | ENSG00000142188.12 | 4.897E-8 | 0 | 29736 | gtex_brain_putamen_basal |
| rs9983740 | 21 | 34822629 | TMEM50B | ENSG00000142188.12 | 1.034E-6 | 0 | 29689 | gtex_brain_putamen_basal |
| rs3183852 | 21 | 34822636 | TMEM50B | ENSG00000142188.12 | 2.155E-8 | 0 | 29682 | gtex_brain_putamen_basal |
| rs2834220 | 21 | 34823252 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 29066 | gtex_brain_putamen_basal |
| rs4817571 | 21 | 34823663 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 28655 | gtex_brain_putamen_basal |
| rs61422135 | 21 | 34824151 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 28167 | gtex_brain_putamen_basal |
| rs928739 | 21 | 34824203 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 28115 | gtex_brain_putamen_basal |
| rs2834221 | 21 | 34824478 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 27840 | gtex_brain_putamen_basal |
| rs2834222 | 21 | 34824771 | TMEM50B | ENSG00000142188.12 | 2.89E-8 | 0 | 27547 | gtex_brain_putamen_basal |
| rs2834223 | 21 | 34825147 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 27171 | gtex_brain_putamen_basal |
| rs2834224 | 21 | 34825318 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 27000 | gtex_brain_putamen_basal |
| rs4481072 | 21 | 34825466 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 26852 | gtex_brain_putamen_basal |
| rs4300927 | 21 | 34825721 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 26597 | gtex_brain_putamen_basal |
| rs2834225 | 21 | 34825875 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 26443 | gtex_brain_putamen_basal |
| rs9305529 | 21 | 34826700 | TMEM50B | ENSG00000142188.12 | 8.437E-8 | 0 | 25618 | gtex_brain_putamen_basal |
| rs10154248 | 21 | 34827112 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 25206 | gtex_brain_putamen_basal |
| rs9974084 | 21 | 34827421 | TMEM50B | ENSG00000142188.12 | 4.897E-8 | 0 | 24897 | gtex_brain_putamen_basal |
| rs3787705 | 21 | 34828637 | TMEM50B | ENSG00000142188.12 | 1.953E-8 | 0 | 23681 | gtex_brain_putamen_basal |
| rs58525092 | 21 | 34829287 | TMEM50B | ENSG00000142188.12 | 1.953E-8 | 0 | 23031 | gtex_brain_putamen_basal |
| rs56884576 | 21 | 34829419 | TMEM50B | ENSG00000142188.12 | 1.524E-7 | 0 | 22899 | gtex_brain_putamen_basal |
| rs2850024 | 21 | 34830968 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 21350 | gtex_brain_putamen_basal |
| rs2834227 | 21 | 34832170 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 20148 | gtex_brain_putamen_basal |
| rs201068471 | 21 | 34832984 | TMEM50B | ENSG00000142188.12 | 1.948E-8 | 0 | 19334 | gtex_brain_putamen_basal |
| rs2245573 | 21 | 34832985 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 19333 | gtex_brain_putamen_basal |
| rs2248340 | 21 | 34833123 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 19195 | gtex_brain_putamen_basal |
| rs2248355 | 21 | 34833329 | TMEM50B | ENSG00000142188.12 | 4.895E-8 | 0 | 18989 | gtex_brain_putamen_basal |
| rs2834229 | 21 | 34834727 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 17591 | gtex_brain_putamen_basal |
| rs13049122 | 21 | 34834957 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 17361 | gtex_brain_putamen_basal |
| rs7283459 | 21 | 34835594 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 16724 | gtex_brain_putamen_basal |
| rs7278056 | 21 | 34835774 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 16544 | gtex_brain_putamen_basal |
| rs13046185 | 21 | 34836091 | TMEM50B | ENSG00000142188.12 | 4.895E-8 | 0 | 16227 | gtex_brain_putamen_basal |
| rs2834230 | 21 | 34836319 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 15999 | gtex_brain_putamen_basal |
| rs2186280 | 21 | 34837144 | TMEM50B | ENSG00000142188.12 | 1.902E-8 | 0 | 15174 | gtex_brain_putamen_basal |
| rs2248820 | 21 | 34837623 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 14695 | gtex_brain_putamen_basal |
| rs68149965 | 21 | 34838167 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 14151 | gtex_brain_putamen_basal |
| rs2471841 | 21 | 34838339 | TMEM50B | ENSG00000142188.12 | 1.953E-8 | 0 | 13979 | gtex_brain_putamen_basal |
| rs2850028 | 21 | 34838589 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 13729 | gtex_brain_putamen_basal |
| rs743334 | 21 | 34839533 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 12785 | gtex_brain_putamen_basal |
| rs13049278 | 21 | 34839756 | TMEM50B | ENSG00000142188.12 | 4.895E-8 | 0 | 12562 | gtex_brain_putamen_basal |
| rs71322215 | 21 | 34840448 | TMEM50B | ENSG00000142188.12 | 2.572E-7 | 0 | 11870 | gtex_brain_putamen_basal |
| rs5843608 | 21 | 34840554 | TMEM50B | ENSG00000142188.12 | 3.073E-8 | 0 | 11764 | gtex_brain_putamen_basal |
| rs13050246 | 21 | 34841869 | TMEM50B | ENSG00000142188.12 | 5.577E-9 | 0 | 10449 | gtex_brain_putamen_basal |
| rs13051161 | 21 | 34842311 | TMEM50B | ENSG00000142188.12 | 1.944E-8 | 0 | 10007 | gtex_brain_putamen_basal |
| rs13047270 | 21 | 34842725 | TMEM50B | ENSG00000142188.12 | 1.947E-8 | 0 | 9593 | gtex_brain_putamen_basal |
| rs13047446 | 21 | 34843014 | TMEM50B | ENSG00000142188.12 | 1.939E-8 | 0 | 9304 | gtex_brain_putamen_basal |
| rs13047352 | 21 | 34843055 | TMEM50B | ENSG00000142188.12 | 1.939E-8 | 0 | 9263 | gtex_brain_putamen_basal |
| rs13051901 | 21 | 34844457 | TMEM50B | ENSG00000142188.12 | 3.893E-9 | 0 | 7861 | gtex_brain_putamen_basal |
| rs35330441 | 21 | 34844874 | TMEM50B | ENSG00000142188.12 | 5.487E-8 | 0 | 7444 | gtex_brain_putamen_basal |
| rs71322217 | 21 | 34845466 | TMEM50B | ENSG00000142188.12 | 1.176E-7 | 0 | 6852 | gtex_brain_putamen_basal |
| rs7277751 | 21 | 34845614 | TMEM50B | ENSG00000142188.12 | 6.222E-8 | 0 | 6704 | gtex_brain_putamen_basal |
| rs7277905 | 21 | 34845708 | TMEM50B | ENSG00000142188.12 | 2.366E-8 | 0 | 6610 | gtex_brain_putamen_basal |
| rs146886032 | 21 | 34846540 | TMEM50B | ENSG00000142188.12 | 4.883E-8 | 0 | 5778 | gtex_brain_putamen_basal |
| rs13049439 | 21 | 34846997 | TMEM50B | ENSG00000142188.12 | 1.776E-6 | 0 | 5321 | gtex_brain_putamen_basal |
| rs2843974 | 21 | 34848517 | TMEM50B | ENSG00000142188.12 | 4.883E-8 | 0 | 3801 | gtex_brain_putamen_basal |
| rs2843722 | 21 | 34848995 | TMEM50B | ENSG00000142188.12 | 1.939E-8 | 0 | 3323 | gtex_brain_putamen_basal |
| rs2734727 | 21 | 34850004 | TMEM50B | ENSG00000142188.12 | 5.138E-7 | 0 | 2314 | gtex_brain_putamen_basal |
| rs2211688 | 21 | 34850744 | TMEM50B | ENSG00000142188.12 | 1.545E-7 | 0 | 1574 | gtex_brain_putamen_basal |
| rs6517175 | 21 | 34857840 | TMEM50B | ENSG00000142188.12 | 9.307E-7 | 0 | -5522 | gtex_brain_putamen_basal |
| rs78293890 | 21 | 34859401 | TMEM50B | ENSG00000142188.12 | 9.964E-7 | 0 | -7083 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| IQGAP2 | 0.79 | 0.34 |
| PDPN | 0.73 | 0.54 |
| AC093251.1 | 0.71 | 0.30 |
| TNC | 0.70 | 0.27 |
| CDO1 | 0.68 | 0.43 |
| PALLD | 0.67 | 0.49 |
| MRC2 | 0.66 | 0.44 |
| PLCE1 | 0.66 | 0.42 |
| PLS3 | 0.66 | 0.35 |
| ZHX2 | 0.66 | 0.39 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.23 | -0.20 |
| AF347015.31 | -0.23 | -0.21 |
| AF347015.8 | -0.23 | -0.22 |
| MT-CYB | -0.23 | -0.22 |
| AF347015.27 | -0.22 | -0.21 |
| AF347015.2 | -0.22 | -0.19 |
| AF347015.33 | -0.22 | -0.21 |
| AF347015.21 | -0.22 | -0.23 |
| AF347015.15 | -0.21 | -0.20 |
| AF347015.26 | -0.21 | -0.18 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| THUM SYSTOLIC HEART FAILURE UP | 423 | 283 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS UP | 372 | 227 | All SZGR 2.0 genes in this pathway |
| GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS YELLOW DN | 23 | 15 | All SZGR 2.0 genes in this pathway |
| GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN | 61 | 35 | All SZGR 2.0 genes in this pathway |
| ELVIDGE HYPOXIA DN | 146 | 94 | All SZGR 2.0 genes in this pathway |
| BIDUS METASTASIS DN | 161 | 93 | All SZGR 2.0 genes in this pathway |
| MAYBURD RESPONSE TO L663536 DN | 56 | 32 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC DN | 537 | 339 | All SZGR 2.0 genes in this pathway |
| ENK UV RESPONSE EPIDERMIS DN | 508 | 354 | All SZGR 2.0 genes in this pathway |
| HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM UP | 81 | 57 | All SZGR 2.0 genes in this pathway |
| TERAMOTO OPN TARGETS CLUSTER 1 | 13 | 10 | All SZGR 2.0 genes in this pathway |
| TOMLINS METASTASIS DN | 20 | 16 | All SZGR 2.0 genes in this pathway |
| MORI PRE BI LYMPHOCYTE DN | 77 | 49 | All SZGR 2.0 genes in this pathway |
| MORI IMMATURE B LYMPHOCYTE UP | 53 | 35 | All SZGR 2.0 genes in this pathway |
| LEE TARGETS OF PTCH1 AND SUFU DN | 83 | 69 | All SZGR 2.0 genes in this pathway |
| SANSOM APC TARGETS DN | 366 | 238 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS LATE PROGENITOR | 544 | 307 | All SZGR 2.0 genes in this pathway |
| MCCLUNG COCAINE REWARD 5D | 79 | 62 | All SZGR 2.0 genes in this pathway |
| DOUGLAS BMI1 TARGETS UP | 566 | 371 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR DN | 911 | 527 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | 1011 | 592 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 | 482 | 296 | All SZGR 2.0 genes in this pathway |
| FOSTER TOLERANT MACROPHAGE DN | 409 | 268 | All SZGR 2.0 genes in this pathway |
| MASSARWEH TAMOXIFEN RESISTANCE UP | 578 | 341 | All SZGR 2.0 genes in this pathway |
| GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
| ALONSO METASTASIS UP | 198 | 128 | All SZGR 2.0 genes in this pathway |
| SWEET LUNG CANCER KRAS UP | 491 | 316 | All SZGR 2.0 genes in this pathway |
| ZHANG TLX TARGETS 60HR UP | 293 | 203 | All SZGR 2.0 genes in this pathway |
| CAIRO LIVER DEVELOPMENT UP | 166 | 105 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| FORTSCHEGGER PHF8 TARGETS DN | 784 | 464 | All SZGR 2.0 genes in this pathway |
| PHONG TNF RESPONSE NOT VIA P38 | 337 | 236 | All SZGR 2.0 genes in this pathway |