Gene Page: C11orf49
Summary ?
| GeneID | 79096 |
| Symbol | C11orf49 |
| Synonyms | - |
| Description | chromosome 11 open reading frame 49 |
| Reference | HGNC:HGNC:28720|Ensembl:ENSG00000149179|HPRD:08332|Vega:OTTHUMG00000166725 |
| Gene type | protein-coding |
| Map location | 11p11.2 |
| Pascal p-value | 7.252E-4 |
| Sherlock p-value | 0.986 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CBLN3 | 0.72 | 0.11 |
| CDH15 | 0.54 | 0.27 |
| GABRA6 | 0.52 | 0.15 |
| SYTL1 | 0.40 | 0.13 |
| MEI1 | 0.33 | 0.07 |
| SNCG | 0.28 | 0.11 |
| ITGB1BP3 | 0.28 | 0.08 |
| SCN4A | 0.27 | 0.09 |
| VWC2 | 0.27 | 0.09 |
| SLC38A8 | 0.27 | 0.12 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SEC14L1 | -0.15 | -0.11 |
| ZNF184 | -0.15 | -0.20 |
| SMURF1 | -0.14 | -0.13 |
| EXD2 | -0.14 | -0.13 |
| STARD7 | -0.14 | -0.18 |
| ZNF189 | -0.14 | -0.16 |
| ADD1 | -0.14 | -0.13 |
| UBE2Q2 | -0.14 | -0.20 |
| PPP1R15B | -0.14 | -0.16 |
| PEX12 | -0.14 | -0.13 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | 70 | 38 | All SZGR 2.0 genes in this pathway |
| APPIERTO RESPONSE TO FENRETINIDE DN | 51 | 35 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| RICKMAN METASTASIS UP | 344 | 180 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC ICP WITH H3K4ME3 | 445 | 257 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |