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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: ISOC2

Summary

GeneID

79763

Symbol

ISOC2

Synonyms

FLJ18582

Description

isochorismatase domain containing 2

Locus tag

Gene type

protein-coding

Map location

19q13.42

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.05

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

CR381670.2

0.39

0.07

PAPOLB

0.38

0.21

DNAH8

0.36

0.14

RP11-413E6.1

0.36

0.08

XIRP1

0.35

0.10

RP1L1

0.33

0.29

CES3

0.32

0.29

FBXW12

0.31

0.26

NUP210L

0.30

0.13

C12orf54

0.30

0.15

Top 10 negatively co-expressed genes

GNG11

-0.21

-0.28

IL32

-0.21

-0.26

CLEC3B

-0.20

-0.23

AC131097.1

-0.19

-0.21

MRPL41

-0.19

CLDN5

-0.19

-0.21

HIGD1B

-0.18

-0.22

AF347015.21

-0.18

-0.29

BTBD17

-0.18

-0.21

METRN

-0.17

-0.25

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003824

catalytic activity

IEA

GO:0005515

protein binding

IPI

15231747

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008152

metabolic process

IEA

GO:0031648

protein destabilization

IMP

17658461

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

17658461

GO:0005737

cytoplasm

IDA

17658461

GO:0005739

mitochondrion

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
LSM8	YJR022W	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	-	HPRD,BioGRID	15231747

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
HOOI_ST7_TARGETS_UP	94	57	All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP	418	263	All SZGR genes in this pathway
BIDUS_METASTASIS_DN	161	93	All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP	380	213	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN	637	377	All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS	988	594	All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP	566	371	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	953	554	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN	1011	592	All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP	388	234	All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12	317	177	All SZGR genes in this pathway
STEIN_ESRRA_TARGETS	535	325	All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN	103	67	All SZGR genes in this pathway
LU_EZH2_TARGETS_UP	295	155	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-33	166	172	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	166	172	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.