Gene Page: DPF3

Summary ?
GeneID8110
SymbolDPF3
SynonymsBAF45C|CERD4
Descriptiondouble PHD fingers 3
ReferenceMIM:601672|HGNC:HGNC:17427|Ensembl:ENSG00000205683|HPRD:03395|Vega:OTTHUMG00000171364
Gene typeprotein-coding
Map location14q24.2
Pascal p-value0.006
Sherlock p-value0.632
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs6687849chr1175904808DPF381100.06trans
rs2481653chr1176044120DPF381100.07trans
rs2502827chr1176044216DPF381100trans
rs12405921chr1206695730DPF381100.15trans
rs17572651chr1218943612DPF381100.03trans
rs16829545chr2151977407DPF381109.864E-12trans
rs3845734chr2171125572DPF381108.59E-6trans
rs1967327chr2179314358DPF381100.1trans
rs7584986chr2184111432DPF381102.175E-9trans
rs2183142chr4159232695DPF381100.06trans
rs17762315chr576807576DPF381104.888E-4trans
rs1368303chr5147672388DPF381100.1trans
rs2530313chr7148112233DPF381100.09trans
rs3118341chr925185518DPF381100.03trans
rs11139334chr984209393DPF381100.02trans
rs2393316chr1059333070DPF381100.13trans
rs11846721chr1463903555DPF381100.15trans
rs17104720chr1477127308DPF381100.11trans
rs16955618chr1529937543DPF381102.374E-27trans
rs3743068chr1579047284DPF381100.16trans
rs17202303chr1663131959DPF381100.13trans
rs1041786chr2122617710DPF381100.01trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
XRCC50.970.97
KLHL70.970.96
MCPH10.970.96
MATR30.970.97
SRP720.970.96
CCT6A0.970.96
NOL110.970.96
WDR30.960.97
POLR2B0.960.96
INTS70.960.95
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.75-0.90
MT-CO2-0.74-0.92
AF347015.33-0.74-0.90
HLA-F-0.74-0.83
FXYD1-0.73-0.91
AF347015.27-0.73-0.89
AIFM3-0.72-0.81
MT-CYB-0.72-0.88
IFI27-0.72-0.88
S100B-0.71-0.85

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ZHOU INFLAMMATORY RESPONSE LIVE DN 384220All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE DN 244147All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA DN 284156All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781465All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP 552347All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP 211136All SZGR 2.0 genes in this pathway
LI LUNG CANCER 4130All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER DN 514319All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE INCIPIENT UP 390242All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 16911088All SZGR 2.0 genes in this pathway
KONDO EZH2 TARGETS 245148All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS GROWING 243155All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS CONFLUENT 567365All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A 898516All SZGR 2.0 genes in this pathway
MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP 259159All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway