Gene Page: TGFBRAP1

Summary
GeneID  9392
Symbol  TGFBRAP1
Synonyms  TRAP-1|TRAP1
Description  transforming growth factor, beta receptor associated protein 1
See related  HGNC:16836|MIM:606237|Ensembl:ENSG00000135966|HPRD:06948|
Locus tag  -
Gene type  protein-coding
Map location  2q12.1-q12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NOP560.880.88
DDX560.870.85
TRAPPC30.870.85
WIBG0.870.87
EXOSC70.860.86
PSMD130.860.87
NGDN0.860.88
KAT50.860.87
C1orf1740.860.85
BCS1L0.850.87
Top 10 negatively co-expressed genes
MT-CO2-0.78-0.74
AF347015.8-0.77-0.76
MT-CYB-0.77-0.76
AF347015.2-0.77-0.77
AF347015.31-0.76-0.75
AF347015.27-0.76-0.77
AF347015.15-0.75-0.76
AF347015.26-0.75-0.77
AF347015.33-0.75-0.74
AF347015.9-0.70-0.73
Gene Ontology
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACVR1BACTRIB | ACVRLK4 | ALK4 | SKR2activin A receptor, type IB-HPRD11278302 
ACVR2BACTRIIB | ActR-IIB | MGC116908activin A receptor, type IIB-HPRD11278302 
ACVRL1ACVRLK1 | ALK-1 | ALK1 | HHT | HHT2 | ORW2 | SKR3 | TSR-Iactivin A receptor type II-like 1-HPRD11278302 
ALOX55-LO | 5-LOX | 5LPG | LOG5 | MGC163204arachidonate 5-lipoxygenase-HPRD,BioGRID10051563 
5LO interacts with TRAP-1.BIND10051563 
BMPR1A10q23del | ACVRLK3 | ALK3 | CD292bone morphogenetic protein receptor, type IA-HPRD11278302 
SMAD2JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2SMAD family member 2-HPRD11278302 
SMAD4DPC4 | JIP | MADH4SMAD family member 4-HPRD,BioGRID11278302 
TGFB1CED | DPD1 | TGFB | TGFbetatransforming growth factor, beta 1Affinity Capture-WesternBioGRID11278302 
TGFB2MGC116892 | TGF-beta2transforming growth factor, beta 2Affinity Capture-WesternBioGRID11278302 
TGFBR1AAT5 | ACVRLK4 | ALK-5 | ALK5 | LDS1A | LDS2A | SKR4 | TGFR-1transforming growth factor, beta receptor 1-HPRD11278302 
TGFBR2AAT3 | FAA3 | LDS1B | LDS2B | MFS2 | RIIC | TAAD2 | TGFR-2 | TGFbeta-RIItransforming growth factor, beta receptor II (70/80kDa)-HPRD11278302 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_SMAD2_3PATHWAY 1713All SZGR genes in this pathway
PID_TGFBR_PATHWAY 5538All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP 316190All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP 329196All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_UP 11168All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN 3823All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE 317190All SZGR genes in this pathway


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