Gene Page: CCND1

Summary
GeneID  595
Symbol  CCND1
Synonyms  BCL1|D11S287E|PRAD1|U21B31
Description  cyclin D1
See related  HGNC:1582|MIM:168461|Ensembl:ENSG00000110092|HPRD:01346|
Locus tag  -
Gene type  protein-coding
Map location  11q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.015 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ARFGAP20.890.87
VPS26B0.890.89
VPS4A0.880.85
RNF1870.880.84
GDI10.880.83
L3MBTL20.860.83
PPP2R2D0.850.82
TBC1D10B0.850.83
CSRP2BP0.850.80
METTL130.850.83
Top 10 negatively co-expressed genes
MT-CO2-0.76-0.74
AF347015.31-0.75-0.74
AF347015.8-0.72-0.73
AF347015.21-0.72-0.70
AF347015.33-0.72-0.69
AF347015.2-0.71-0.69
HIGD1B-0.71-0.73
MT-CYB-0.71-0.70
FXYD1-0.71-0.73
AF347015.26-0.70-0.68
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15232106 |17254966 |17274640 
|17334399 
GO:0004672protein kinase activityIEA-
GO:0016538cyclin-dependent protein kinase regulator activityIEA-
GO:0019901protein kinase bindingIPI8114739 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000082G1/S transition of mitotic cell cycleNAS-
GO:0000320re-entry into mitotic cell cycleIEA-
GO:0001934positive regulation of protein amino acid phosphorylationIDA8114739 
GO:0030968endoplasmic reticulum unfolded protein responseIEA-
GO:0051301cell divisionIEA-
GO:0045737positive regulation of cyclin-dependent protein kinase activityIDA8114739 
GO:0045444fat cell differentiationIEA-
GO:0051726regulation of cell cycleIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000307cyclin-dependent protein kinase holoenzyme complexIEA-
GO:0005829cytosolEXP9106657 
GO:0005829cytosolIEA-
GO:0005575cellular_componentND-
GO:0005622intracellularIDA11256614 
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP9190208 |16782892 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKAP8AKAP95 | DKFZp586B1222A kinase (PRKA) anchor protein 8-HPRD,BioGRID14641107 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptor-HPRD,BioGRID10344732 
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onset-HPRD,BioGRID9244350 
BRCA1 associates with Cyclin D1BIND9244350 
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD9837900 
CCNDBP1DIP1 | GCIPcyclin D-type binding-protein 1-HPRD,BioGRID10801854 
CDK4CMM3 | MGC14458 | PSK-J3cyclin-dependent kinase 4-HPRD9150368 |9837900 
CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species.BIND9228064 
CCND1 (cyclin D1) interacts with CDK4.BIND8662825 
Affinity Capture-Western
Reconstituted Complex		BioGRID8259215 |9837900 
|10580009 |11360184 
CDK6MGC59692 | PLSTIRE | STQTL11cyclin-dependent kinase 6Affinity Capture-Western
Reconstituted Complex		BioGRID10580009 |11360184 
-HPRD11739795 
CCND1 (cyclin D1) interacts with CDK6.BIND12867429 
CDKN1ACAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1cyclin-dependent kinase inhibitor 1A (p21, Cip1)-HPRD,BioGRID7478582 |8657154 
p21 interacts with cyclin D.BIND9632134 
Cyclin D1 interacts with p21.BIND8999999 
CDKN1A (p21) interacts with CCND1 (cyclin D1).BIND8662825 
CDKN1BCDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1cyclin-dependent kinase inhibitor 1B (p27, Kip1)in vitro
Reconstituted Complex		BioGRID10908655 |11360184 
p27 interacts with cyclin D.BIND9632134 
-HPRD7478582 |10908655 
CDKN1CBWCR | BWS | KIP2 | WBS | p57cyclin-dependent kinase inhibitor 1C (p57, Kip2)Reconstituted ComplexBioGRID10764802 
CDKN2AARF | CDK4I | CDKN2 | CMM2 | INK4 | INK4a | MLM | MTS1 | TP16 | p14 | p14ARF | p16 | p16INK4 | p16INK4a | p19cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)Reconstituted ComplexBioGRID10580009 
CDKN2DINK4D | p19 | p19-INK4Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)-HPRD7739547 
CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinaseIKK-alpha interacts with cyclin D1 promoter.BIND15808510 
CREB1CREB | MGC9284cAMP responsive element binding protein 1CREB interacts with CRE.BIND15897899 
CREBBPCBP | KAT3A | RSTSCREB binding proteinCBP interacts with cyclin D1 promoter.BIND15808510 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDaCTNNB1 (beta-catenin) interacts with the CCND1 promoter.BIND15592430 
-HPRD11836555 
CUL3-cullin 3-HPRD10500095 
DMTF1DMP1 | DMTF | FLJ41265 | hDMP1cyclin D binding myb-like transcription factor 1-HPRD8887674 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)An unspecified isoform of EGFR binds to Cyclin D1 promoter.BIND15950906 
EP300KAT3B | p300E1A binding protein p300-HPRD,BioGRID11788592 
ERCC3BTF2 | GTF2H | RAD25 | TFIIH | XPBexcision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)TFIIH interacts with Cyclin D1 promoter.BIND15893730 
ESR1DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1estrogen receptor 1-HPRD,BioGRID9039267 
ER-alpha interacts with cyclin D1 promoter.BIND15808510 
FOXO4AFX | AFX1 | MGC120490 | MLLT7forkhead box O4MLLT7 (FOXO4) interacts with the CCND1 (Cyclin D1) promoter. This interaction was modelled on a demonstrated interaction between MLLT7 and CCND1 both from unspecified species.BIND15688030 
HDAC3HD3 | RPD3 | RPD3-2histone deacetylase 3Affinity Capture-WesternBioGRID12048199 |15558026 
HERC5CEB1 | CEBP1hect domain and RLD 5-HPRD,BioGRID10581175 
IFI27FAM14D | ISG12 | ISG12A | P27interferon, alpha-inducible protein 27-HPRD9837900 
KAT2BCAF | P | P/CAF | PCAFK(lysine) acetyltransferase 2B-HPRD,BioGRID10318892 
KLF6BCD1 | COPEB | CPBP | DKFZp686N0199 | GBF | PAC1 | ST12 | ZF9Kruppel-like factor 6KLF6 interacts with Cyclin D1.BIND15172998 
MCM10CNA43 | DNA43 | MGC126776 | PRO2249minichromosome maintenance complex component 10-HPRD15232106 
MYBL2B-MYB | BMYB | MGC15600v-myb myeloblastosis viral oncogene homolog (avian)-like 2-HPRD10645009 
NCOA1F-SRC-1 | KAT13A | MGC129719 | MGC129720 | NCoA-1 | RIP160 | SRC-1 | SRC1 | bHLHe42nuclear receptor coactivator 1-HPRD,BioGRID9832502 
NCOA3ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIPnuclear receptor coactivator 3-HPRD,BioGRID9832502 
AIB1 interacts with cyclin D1 promoter.BIND15808510 
NEUROD1BETA2 | BHF-1 | NEUROD | bHLHa3neurogenic differentiation 1Affinity Capture-Western
Phenotypic Suppression		BioGRID11788592 
NPDC1CAB | CAB- | CAB-1 | CAB1 | DKFZp586J0523neural proliferation, differentiation and control, 1-HPRD,BioGRID11042687 
PCNAMGC8367proliferating cell nuclear antigenReconstituted ComplexBioGRID7908906 
PIN1DOD | UBL5peptidylprolyl cis/trans isomerase, NIMA-interacting 1PIN1 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human PIN1 and Cyclin D1 from an unspecified species.BIND11805292 
POLR2AMGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1polymerase (RNA) II (DNA directed) polypeptide A, 220kDaPol II interacts with cyclin D1 promoter.BIND15808510 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human.BIND11126356 
-HPRD,BioGRID8490963 
RBL1CP107 | MGC40006 | PRB1 | p107retinoblastoma-like 1 (p107)-HPRD,BioGRID8643455 
RBX1BA554C12.1 | MGC13357 | MGC1481 | RNF75 | ROC1ring-box 1-HPRD,BioGRID11311237 
RELAMGC131774 | NFKB3 | p65v-rel reticuloendotheliosis viral oncogene homolog A (avian)RELA (NF-kappaB p65 subunit) interacts with the CCND1 (Cyclin D1) promoter.BIND15652748 
RFC1A1 | MGC51786 | MHCBFB | PO-GA | RECC1 | RFC | RFC140replication factor C (activator 1) 1, 145kDa-HPRD,BioGRID10353443 
STAT3APRF | FLJ20882 | HIES | MGC16063signal transducer and activator of transcription 3 (acute-phase response factor)An unspecified isoform of STAT3 binds to Cyclin D1 promoter.BIND15950906 
-HPRD,BioGRID11279133 
TAF1BA2R | CCG1 | CCGS | DYT3 | KAT4 | N-TAF1 | NSCL2 | OF | P250 | TAF2A | TAFII250TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDaTAFII250 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between TAFII250 from human and Cyclin D1 from mouse.BIND11126356 
-HPRD,BioGRID9926939 |11126356 
THRAAR7 | EAR7 | ERB-T-1 | ERBA | ERBA1 | MGC000261 | MGC43240 | NR1A1 | THRA1 | THRA2 | c-ERBA-1thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)-HPRD,BioGRID12048199 
THRBERBA-BETA | ERBA2 | GRTH | MGC126109 | MGC126110 | NR1A2 | PRTH | THR1 | THRB1 | THRB2thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)Affinity Capture-Western
Reconstituted Complex		BioGRID12048199 
TSC2FLJ43106 | LAM | TSC4tuberous sclerosis 2Affinity Capture-WesternBioGRID16357142 
XPO1CRM1 | DKFZp686B1823exportin 1 (CRM1 homolog, yeast)Reconstituted ComplexBioGRID12529437 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_CYCLE 12884All SZGR genes in this pathway
KEGG_P53_SIGNALING_PATHWAY 6945All SZGR genes in this pathway
KEGG_WNT_SIGNALING_PATHWAY 151112All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER 6247All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER 7056All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER 5245All SZGR genes in this pathway
KEGG_GLIOMA 6556All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_THYROID_CANCER 2926All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
KEGG_BLADDER_CANCER 4233All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA 6047All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
KEGG_NON_SMALL_CELL_LUNG_CANCER 5447All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
BIOCARTA_CARM_ER_PATHWAY 3527All SZGR genes in this pathway
BIOCARTA_G1_PATHWAY 2821All SZGR genes in this pathway
BIOCARTA_CELLCYCLE_PATHWAY 2315All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY 2726All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_P53_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_WNT_PATHWAY 2624All SZGR genes in this pathway
WNT_SIGNALING 8971All SZGR genes in this pathway
SA_G1_AND_S_PHASES 1510All SZGR genes in this pathway
SA_REG_CASCADE_OF_CYCLIN_EXPR 137All SZGR genes in this pathway
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
PID_AR_PATHWAY 6146All SZGR genes in this pathway
PID_FRA_PATHWAY 3728All SZGR genes in this pathway
PID_PS1_PATHWAY 4639All SZGR genes in this pathway
PID_ILK_PATHWAY 4532All SZGR genes in this pathway
PID_TELOMERASE_PATHWAY 6848All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY 3933All SZGR genes in this pathway
PID_ATF2_PATHWAY 5943All SZGR genes in this pathway
PID_AP1_PATHWAY 7060All SZGR genes in this pathway
PID_FOXM1_PATHWAY 4030All SZGR genes in this pathway
PID_TRKR_PATHWAY 6248All SZGR genes in this pathway
PID_CMYB_PATHWAY 8461All SZGR genes in this pathway
PID_ERA_GENOMIC_PATHWAY 6537All SZGR genes in this pathway
PID_P38_GAMMA_DELTA_PATHWAY 119All SZGR genes in this pathway
PID_BETA_CATENIN_NUC_PATHWAY 8060All SZGR genes in this pathway
PID_MYC_REPRESS_PATHWAY 6352All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY 3631All SZGR genes in this pathway
PID_RB_1PATHWAY 6546All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 2917All SZGR genes in this pathway
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 4424All SZGR genes in this pathway
REACTOME_CELL_CYCLE_MITOTIC 325185All SZGR genes in this pathway
REACTOME_G1_PHASE 3823All SZGR genes in this pathway
REACTOME_MITOTIC_G1_G1_S_PHASES 13779All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH 10364All SZGR genes in this pathway
REACTOME_S_PHASE 10966All SZGR genes in this pathway
PYEON_HPV_POSITIVE_TUMORS_DN 105All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_6HR_DN 1813All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN 182111All SZGR genes in this pathway
WILCOX_RESPONSE_TO_PROGESTERONE_DN 6644All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_UP 13378All SZGR genes in this pathway
NOJIMA_SFRP2_TARGETS_DN 2518All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_DN 3319All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_UP 1410All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP 265158All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP 5839All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP 12672All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_DN 229142All SZGR genes in this pathway
CHIN_BREAST_CANCER_COPY_NUMBER_UP 2718All SZGR genes in this pathway
VANHARANTA_UTERINE_FIBROID_UP 4526All SZGR genes in this pathway
CAIRO_PML_TARGETS_BOUND_BY_MYC_DN 1412All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_UP 15093All SZGR genes in this pathway
BARIS_THYROID_CANCER_DN 5945All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP 5844All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_UP 4429All SZGR genes in this pathway
HUMMERICH_MALIGNANT_SKIN_TUMOR_UP 168All SZGR genes in this pathway
BUSA_SAM68_TARGETS_UP 76All SZGR genes in this pathway
MARKS_HDAC_TARGETS_DN 1511All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN 8463All SZGR genes in this pathway
BAKER_HEMATOPOIESIS_STAT3_TARGETS 1612All SZGR genes in this pathway
BAKER_HEMATOPOESIS_STAT5_TARGETS 77All SZGR genes in this pathway
SANCHEZ_MDM2_TARGETS 1510All SZGR genes in this pathway
SCHEIDEREIT_IKK_TARGETS 1815All SZGR genes in this pathway
SUZUKI_AMPLIFIED_IN_ORAL_CANCER 1612All SZGR genes in this pathway
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23 2413All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_1 5133All SZGR genes in this pathway
MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS 3625All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS 5845All SZGR genes in this pathway
HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 1812All SZGR genes in this pathway
SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS 3727All SZGR genes in this pathway
SCHRAMM_INHBA_TARGETS_UP 77All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP 176111All SZGR genes in this pathway
BORLAK_LIVER_CANCER_EGF_UP 5741All SZGR genes in this pathway
OXFORD_RALA_OR_RALB_TARGETS_UP 4823All SZGR genes in this pathway
MAINA_VHL_TARGETS_DN 1814All SZGR genes in this pathway
SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN 3126All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
OHM_METHYLATED_IN_ADULT_CANCERS 2723All SZGR genes in this pathway
GROSS_ELK3_TARGETS_UP 2716All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_UP 209139All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN 10371All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP 139All SZGR genes in this pathway
FRIDMAN_SENESCENCE_UP 7760All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
AMIT_EGF_RESPONSE_60_HELA 4632All SZGR genes in this pathway
AMIT_EGF_RESPONSE_480_HELA 164118All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_3 2823All SZGR genes in this pathway
LEE_TARGETS_OF_PTCH1_AND_SUFU_UP 5337All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON 15893All SZGR genes in this pathway
STANELLE_E2F1_TARGETS 2920All SZGR genes in this pathway
CHESLER_BRAIN_QTL_CIS 7551All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_TGFA_UP 6140All SZGR genes in this pathway
WILLERT_WNT_SIGNALING 2413All SZGR genes in this pathway
LIN_APC_TARGETS 7755All SZGR genes in this pathway
LE_EGR2_TARGETS_UP 10875All SZGR genes in this pathway
BECKER_TAMOXIFEN_RESISTANCE_DN 5237All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
ROSS_AML_WITH_AML1_ETO_FUSION 7655All SZGR genes in this pathway
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION 8868All SZGR genes in this pathway
VERNELL_RETINOBLASTOMA_PATHWAY_DN 2213All SZGR genes in this pathway
HOFMANN_CELL_LYMPHOMA_UP 5035All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_SPIKED 2213All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP 2622All SZGR genes in this pathway
STAEGE_EWING_FAMILY_TUMOR 3322All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN 408274All SZGR genes in this pathway
RAMALHO_STEMNESS_UP 206118All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_DN 8666All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_UP 8648All SZGR genes in this pathway
SIMBULAN_PARP1_TARGETS_UP 3123All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
ZHANG_PROLIFERATING_VS_QUIESCENT 5141All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_DN 6444All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
BURTON_ADIPOGENESIS_7 5134All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 163113All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN 14192All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION 8865All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G 9562All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_UP 7353All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_UP 11580All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 9175All SZGR genes in this pathway
LABBE_WNT3A_TARGETS_UP 11271All SZGR genes in this pathway
CLIMENT_BREAST_CANCER_COPY_NUMBER_UP 2320All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP 6229All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
BEIER_GLIOMA_STEM_CELL_DN 6642All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP 2719All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_UP 8962All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN 3020All SZGR genes in this pathway
HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_UP 2414All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY 106All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_DN 168All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_DN 251151All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_PCA3_UP 8054All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_12HR_DN 3325All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_24HR_DN 4332All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_32HR_DN 3928All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_48HR_DN 4029All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 172107All SZGR genes in this pathway
SUBTIL_PROGESTIN_TARGETS 3625All SZGR genes in this pathway
CARD_MIR302A_TARGETS 7762All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_DN 213127All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
IVANOVSKA_MIR106B_TARGETS 9056All SZGR genes in this pathway
WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 5739All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
WACKER_HYPOXIA_TARGETS_OF_VHL 1311All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
DELACROIX_RAR_TARGETS_DN 2416All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
BOUDOUKHA_BOUND_BY_IGF2BP2 11159All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/98221422201Ahsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
miR-1/206100010061Ahsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-15/16/195/424/497203320401A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-17-5p/20/93.mr/106/519.d10141020m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-19177817851A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2321712177m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-323217021771A,m8hsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-338907913m8hsa-miR-338brainUCCAGCAUCAGUGAUUUUGUUGA
miR-34/449207620821Ahsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-503196019671A,m8hsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
hsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-93.hd/291-3p/294/295/302/372/373/52010131019m8hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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