Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 36 literature records
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1
Entrez ID
Description
5728
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region.
5728
Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer.
2296
FOXC1 functions as a tumor suppressor through TGF-beta1 mediated signals.
838
Caspase-5 might be a suppressor gene of highly metastatic potential in lung cancer
1801
OVCA1: emerging as a bona fide tumor suppressor.
7157
p53 protein expression is closely associated with decidual transformation indicates a novel role for this tumor suppressor in regulating human endometrial function.
7249
Prostaglandin E2 mediates phosphorylation and down-regulation of the tuberous sclerosis-2 tumor suppressor (tuberin) in human endometrial adenocarcinoma cells via the Akt signaling pathway.
4436
"Tumor suppressor gene, hMSH2, may play an important role as a putative coactivator in ER alpha dependent gene expression."
5178
"Loss of PEG3 expression may be a frequent event in gynecologic cancers. Given the known role of PEG3 in p53-mediated apoptosis, it is possible that PEG3 functions as a tumor suppressor."
54583
"EGLN1 can be considered as a candidate tumor suppressor on chromosome 1q, and our observation could open the new aspect in exploring the machinery of senescence induction associated with hypoxia-inducible factor 1, alpha signal transduction"
5728
[Pathogenic role of PTEN tumor suppressor gene in ovarian cancer associated to endometriosis].
5074
Par-4 is a relevant tumor suppressor gene in human endometrial carcinogenesis.
2308
FOXO1 serves as a tumor suppressor in endometrial cancer cells and is involved in normal growth control and maintenance of genomic stability.
9447
The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
580
Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
7157
Genetic alterations of the p53 tumor suppressor gene were seen in a mixed serous carcinoma of the endometrium.
1029
Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.
1030
Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.
1029
CDK inhibitor p16 tumor suppressors were genes activated in early endometrial endometrioid carcinoma (stages I-II).
347745
"Results suggest that, in breast cancer, Par-4 plays a similar tumor suppressor gene role as reported in endometrial carcinoma, and that Par-4 expression has a significant inverse association with expression of progesterone receptor."
5074
"Results suggest that, in breast cancer, Par-4 plays a similar tumor suppressor gene role as reported in endometrial carcinoma, and that Par-4 expression has a significant inverse association with expression of progesterone receptor."
255082
Long non-coding RNA CASC2 suppresses malignancy in human gliomas by miR-21.
255082
"Our findings strongly suggest that CASC2a may act as a tumour suppressor gene, with both epigenetic and genetic alterations concurring to gene inactivation."
23513
"hScrib, a human homolog of Drosophila neoplastic tumor suppressor, is involved in the progress of endometrial cancer."
7545
"ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer."
324
Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer.
5728
Immunohistochemical phospho tensin tumor suppressor gene staining patterns in endometrial hyperplasias: a 2-year study.
406989
Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ER??-positive endometrioid adenocarcinoma.
3169
These results suggest that FOXA1 functions as a tumor suppressor through modulation of proliferation and migration of endometrial cancer cells.
4640
findings suggest that MYO1A has tumor suppressor activity in the normal gastric epithelium but not in the normal endometrium and inactivation of MYO1A either genetically or epigenetically may confer gastric epithelial cells a growth ad
406929
miR-138 acts as a tumor suppressor and may prevent metastasis.
79648
"in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is regulated by miR-27a"
2950
The results indicate that aberrant CpG methylation of the promoter region in the GSTP1 and RASSF1A tumor-suppressor genes is an important event in carcinogenesis of endometrial cancer and may have an impact on tumor aggressiveness
81848
SPRY4 may function as a tumor suppressor in endometrial adenocarcinoma.
5728
Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.
5728
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice.
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