Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 616 literature records
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Entrez ID
Description
1029
Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.
9940
"Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3."
4763
Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation.
4221
"Primary structure, gene expression and chromosomal mapping of rodent homologs of the MEN1 tumor suppressor gene."
50514
"Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32."
26524
"Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts."
3621
Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions.
274
Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma.
634
"C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers."
7268
"TTC4, a novel candidate tumor suppressor gene at 1p31 is often mutated in malignant melanoma of the skin."
7982
Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31.
23705
TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer.
310
"ANX7, a candidate tumor suppressor gene for prostate cancer."
11186
"Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers."
5325
Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities.
8635
Cloning and characterization of a senescence inducing and class II tumor suppressor gene in ovarian carcinoma at chromosome region 6q27. We therefore propose that RNASE6PL may be a candidate for the 6q27 senescence inducing and class II tumor suppressor gene in ovarian cancer.
11186
"The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis."
5728
The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival.
5655
Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue.
11145
"hH-Rev107, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors."
199731
"Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins."
51741
WWOX: a candidate tumor suppressor gene involved in multiple tumor types.
11334
Overexpression of candidate tumor suppressor geneFUS1 isolated from the 3p21.3 homozygous deletionregion leads to G1 arrest and growth inhibition oflung cancer cells.
112464
Human SRBC is located within the 11p15.5-p15.4 tumor suppressor region and is inactivated in breast and lung cancers.
672
The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
1316
data suggest that KLF6 is a tumor suppressor gene involved in human prostate cancer
7157
Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A
7157
Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A.
1029
The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development
2719
Candidate lung tumor suppressor gene which may be regulated by tobacco exposure.
5728
Primary malignant lymphoma of the brain: analysis of MMAC1 (PTEN) tumor suppressor gene.
11186
RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1.
5915
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer.
11200
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.
11145
Silencing of the mouse H-rev107 gene encoding a class II tumor suppressor by CpG methylation.
1029
Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
1030
Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
11186
The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells.
23635
"Member of a closely related, evolutionarily conserved, and ubiquitously expressed gene family, potential tumor suppressor"
54556
"Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers."
7249
Aberrant expression of HMGA2 in uterine leiomyoma is associated with loss of TSC2 tumor suppressor gene function.
148252
Rig a novel Ras-related protein and potential neural tumor suppressor (RIG)
4771
Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway
857
Results indicate a central role for caveolin-1 in promoting cellular senescence and suggest the hypothesis that premature senescence may represent a tumor suppressor function mediated by caveolin-1 in vivo.
863
CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.
84700
"MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer"
7020
Results indicate that the tumor suppressor activity of AP2alpha is mediated through a direct interaction with p53.
581
"BAX and BAK mediate p53-independent suppression of tumorigenesis. Thus, BAX and BAK function to suppress tumorigenesis, and their deficiency was selected for in vivo. "
9353
"SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers."
3728
function as an inhibitor of beta-catenin/TCF-dependent gene transcription and role as a potentially novel tumor suppressor protein in a subset of human NSCLC cancers
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