| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046591 | HBV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
| TVIS30082845 | HIV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRA1 |
|---|---|
| DrugBank ID | DB11582 |
| Drug Name | Thiocolchicoside |
| Target ID | BE0004797 |
| UniProt ID | Q9UN88 |
| Regulation Type | antagonist |
| PubMed IDs | 16806306; 17234181 |
| Citations | Carta M, Murru L, Botta P, Talani G, Sechi G, De Riu P, Sanna E, Biggio G: The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. Neuropharmacology. 2006 Sep;51(4):805-15. Epub 2006 Jun 30.@@Mascia MP, Bachis E, Obili N, Maciocco E, Cocco GA, Sechi GP, Biggio G: Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes. Eur J Pharmacol. 2007 Mar 8;558(1-3):37-42. Epub 2006 Dec 12. |
| Groups | Experimental |
| Direct Classification | Phenolic glycosides |
| SMILES | COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C2CC[C@H](NC(C)=O)C3=CC(=O)C(SC)=CC=C3C2=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL213907 |
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