Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046591HBVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TVIS30082845HIVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TCGA Plot Options
Drug Information
GeneGABRA1
DrugBank IDDB00474
Drug NameMethohexital
Target IDBE0000795
UniProt IDP14867
Regulation Typeantagonist
PubMed IDs17139284; 17016423; 9014160; 11752352
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Koltchine VV, Ye Q, Finn SE, Harrison NL: Chimeric GABAA/glycine receptors: expression and barbiturate pharmacology. Neuropharmacology. 1996;35(9-10):1445-56.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsApproved
Direct ClassificationBarbituric acid derivatives
SMILESCCC#CC(C)C1(CC=C)C(=O)NC(=O)N(C)C1=O
Pathways
PharmGKBPA164784030
ChEMBLCHEMBL7413