Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046591HBVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TVIS30082845HIVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TCGA Plot Options
Drug Information
GeneGABRA1
DrugBank IDDB01236
Drug NameSevoflurane
Target IDBE0004797
UniProt IDQ9UN88
Regulation Typeagonist
PubMed IDs7509043; 29039138
CitationsFranks NP, Lieb WR: Molecular and cellular mechanisms of general anaesthesia. Nature. 1994 Feb 17;367(6464):607-14. doi: 10.1038/367607a0.@@Brohan J, Goudra BG: The Role of GABA Receptor Agonists in Anesthesia and Sedation. CNS Drugs. 2017 Oct;31(10):845-856. doi: 10.1007/s40263-017-0463-7.
GroupsApproved; Vet_approved
Direct ClassificationDialkyl ethers
SMILESFCOC(C(F)(F)F)C(F)(F)F
Pathways
PharmGKBPA451341
ChEMBLCHEMBL1200694