Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046591HBVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TVIS30082845HIVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TCGA Plot Options
Drug Information
GeneGABRA1
DrugBank IDDB00228
Drug NameEnflurane
Target IDBE0004797
UniProt IDQ9UN88
Regulation Typepotentiator
PubMed IDs16402123; 16973644; 11465594
CitationsFranks NP: Molecular targets underlying general anaesthesia. Br J Pharmacol. 2006 Jan;147 Suppl 1:S72-81.@@Grasshoff C, Antkowiak B: Effects of isoflurane and enflurane on GABAA and glycine receptors contribute equally to depressant actions on spinal ventral horn neurones in rats. Br J Anaesth. 2006 Nov;97(5):687-94. doi: 10.1093/bja/ael239. Epub 2006 Sep 13.@@Greenblatt EP, Meng X: Divergence of volatile anesthetic effects in inhibitory neurotransmitter receptors. Anesthesiology. 2001 Jun;94(6):1026-33.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationOrganofluorides
SMILESFC(F)OC(F)(F)C(F)Cl
Pathways
PharmGKBPA449461
ChEMBLCHEMBL1257