Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046591HBVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TVIS30082845HIVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TCGA Plot Options
Drug Information
GeneGABRA1
DrugBank IDDB00363
Drug NameClozapine
Target IDBE0000795
UniProt IDP14867
Regulation Typeantagonist
PubMed IDs8532064; 9016840
CitationsKorpi ER, Wong G, Luddens H: Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine. Naunyn Schmiedebergs Arch Pharmacol. 1995 Oct;352(4):365-73. doi: 10.1007/BF00172773.@@Squires RF, Saederup E: Clozapine and some other antipsychotic drugs may preferentially block the same subset of GABA(A) receptors. Neurochem Res. 1997 Feb;22(2):151-62. doi: 10.1023/a:1027359422433.
GroupsApproved
Direct ClassificationDibenzodiazepines
SMILESCN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
Pathways
PharmGKBPA449061
ChEMBLCHEMBL42