VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS10046591 | HBV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
TVIS30082845 | HIV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | GABRA1 |
---|---|
DrugBank ID | DB01043 |
Drug Name | Memantine |
Target ID | BE0004797 |
UniProt ID | Q9UN88 |
Regulation Type | binder |
PubMed IDs | 19236854 |
Citations | Molinaro G, Battaglia G, Riozzi B, Di Menna L, Rampello L, Bruno V, Nicoletti F: Memantine treatment reduces the expression of the K(+)/Cl(-) cotransporter KCC2 in the hippocampus and cerebral cortex, and attenuates behavioural responses mediated by GABA(A) receptor activation in mice. Brain Res. 2009 Apr 10;1265:75-9. doi: 10.1016/j.brainres.2009.02.016. Epub 2009 Feb 21. |
Groups | Approved; Investigational |
Direct Classification | Monoalkylamines |
SMILES | CC12CC3CC(C)(C1)CC(N)(C3)C2 |
Pathways | |
PharmGKB | PA10364 |
ChEMBL | CHEMBL807 |
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