Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046591HBVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TVIS30082845HIVENSG00000022355.18protein_codingGABRA1NoNo2554P14867
TCGA Plot Options
Drug Information
GeneGABRA1
DrugBank IDDB01043
Drug NameMemantine
Target IDBE0004797
UniProt IDQ9UN88
Regulation Typebinder
PubMed IDs19236854
CitationsMolinaro G, Battaglia G, Riozzi B, Di Menna L, Rampello L, Bruno V, Nicoletti F: Memantine treatment reduces the expression of the K(+)/Cl(-) cotransporter KCC2 in the hippocampus and cerebral cortex, and attenuates behavioural responses mediated by GABA(A) receptor activation in mice. Brain Res. 2009 Apr 10;1265:75-9. doi: 10.1016/j.brainres.2009.02.016. Epub 2009 Feb 21.
GroupsApproved; Investigational
Direct ClassificationMonoalkylamines
SMILESCC12CC3CC(C)(C1)CC(N)(C3)C2
Pathways
PharmGKBPA10364
ChEMBLCHEMBL807