| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046591 | HBV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
| TVIS30082845 | HIV | ENSG00000022355.18 | protein_coding | GABRA1 | No | No | 2554 | P14867 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRA1 |
|---|---|
| DrugBank ID | DB00690 |
| Drug Name | Flurazepam |
| Target ID | BE0004797 |
| UniProt ID | Q9UN88 |
| Regulation Type | positive allosteric modulator |
| PubMed IDs | 23038269; 29950725 |
| Citations | Sigel E, Steinmann ME: Structure, function, and modulation of GABA(A) receptors. J Biol Chem. 2012 Nov 23;287(48):40224-31. doi: 10.1074/jbc.R112.386664. Epub 2012 Oct 4.@@Zhu S, Noviello CM, Teng J, Walsh RM Jr, Kim JJ, Hibbs RE: Structure of a human synaptic GABAA receptor. Nature. 2018 Jul;559(7712):67-72. doi: 10.1038/s41586-018-0255-3. Epub 2018 Jun 27. |
| Groups | Approved; Illicit; Investigational |
| Direct Classification | 1,4-benzodiazepines |
| SMILES | CCN(CC)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1F |
| Pathways | |
| PharmGKB | PA449681 |
| ChEMBL | CHEMBL968 |
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