DegronMD - P46821(MAP1B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M1841L	TCGA-18-3409	LUSC	TCGA	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation rewiring degron network	0.0556
p.M1841L	DO26444	LUSC	ICGC	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation rewiring degron network	0.0556
p.D520N	TCGA-24-1842	OV	TCGA	DLTGQVPTP	DEG_COP1_1	520:528	Mutation altering degron motif	0.6932
p.D520N	DO27972	OV	ICGC	DLTGQVPTP	DEG_COP1_1	520:528	Mutation altering degron motif	0.6932
p.T2037A	TCGA-34-7107	LUSC	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation altering degron motif	0.825
p.T2037A	DO26449	LUSC	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation altering degron motif	0.825
p.S1127Y	TCGA-4Z-AA7M	BLCA	TCGA	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.25
p.S1127Y	DO218976	BLCA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.25
p.T2049S	TCGA-55-A490	LUAD	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.6005
p.T2049S	DO24596	LUAD	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.6005
p.A1550S	TCGA-66-2763	LUSC	TCGA	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1389
p.A1550S	DO27620	LUSC	ICGC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1389
p.P1854H	TCGA-A6-3809	COAD	TCGA	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation altering degron motif	0.7694
p.P1854H	DO8722	COAD	ICGC	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation altering degron motif	0.7694
p.S1262Y	TCGA-AA-3697	COAD	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation blocking phosphorylation signal	0.6389
p.S1262Y	DO8424	COAD	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation blocking phosphorylation signal	0.6389
p.S1127T	TCGA-AA-3811	COAD	TCGA	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.25
p.S1127T	DO7962	COAD	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.25
p.S1792P	TCGA-AA-3966	COAD	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation altering degron motif	0.7863
p.S1792P	DO10068	COAD	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation altering degron motif	0.7863
p.E2046D	TCGA-AA-3984	COAD	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.2778
p.E2046D	TCGA-AA-3984	COAD	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.1389
p.E2046D	TCGA-AG-A002	READ	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.2778
p.E2046D	TCGA-AG-A002	READ	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.1389
p.E2046D	TCGA-E6-A1LX	UCEC	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.2778
p.E2046D	TCGA-E6-A1LX	UCEC	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.1389
p.E2046D	DO9002	COAD	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.2778
p.E2046D	DO9002	COAD	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.1389
p.E2046D	DO41020	UCEC	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.2778
p.E2046D	DO41020	UCEC	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.1389
p.A516T	TCGA-AA-A010	COAD	TCGA	DLTGQVPTP	DEG_COP1_1	520:528	Mutation rewiring degron network	0.2222
p.D1569N	TCGA-AA-A010	COAD	TCGA	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.R2033Q	TCGA-AA-A010	COAD	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2778
p.R2033Q	TCGA-EO-A22U	UCEC	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2778
p.R2033Q	DO43755	UCEC	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2778
p.P1261S	TCGA-AJ-A3EK	UCEC	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.P1261S	TCGA-EE-A20C	SKCM	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.P1261S	DO222775	MELA	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.P1261S	DO47665	SKCM	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.P1261S	DO41584	UCEC	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.D1568N	TCGA-AX-A05Z	UCEC	TCGA	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1389
p.D1568N	DO40884	UCEC	ICGC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1389
p.A1742T	TCGA-AX-A2HD	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1111
p.A1742T	TCGA-F5-6814	READ	TCGA	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1111
p.A1742T	DO36556	READ	ICGC	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1111
p.A1742T	DO42608	UCEC	ICGC	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1111
p.K1269N	TCGA-AZ-4315	COAD	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.5806
p.K1269N	DO8842	COAD	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.5806
p.E2060D	TCGA-B0-5080	KIRC	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2060D	TCGA-D1-A17Q	UCEC	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2060D	DO18154	KIRC	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2060D	DO41903	UCEC	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.L1272M	TCGA-BA-6869	HNSC	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.5999
p.L1272M	DO14250	HNSC	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.5999
p.E1776D	TCGA-BK-A6W3	UCEC	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.0556
p.E1776D	DO50076	UCEC	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.0556
p.R1275H	TCGA-BR-4371	STAD	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275H	TCGA-C5-A1MI	CESC	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275H	TCGA-CH-5738	PRAD	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275H	DO6249	CESC	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275H	DO36370	PRAD	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275H	DO38348	STAD	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.Y1972H	TCGA-BR-6452	STAD	TCGA	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation blocking phosphorylation signal	0.5556
p.Y1972H	DO38404	STAD	ICGC	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation blocking phosphorylation signal	0.5556
p.S1801L	TCGA-CV-7406	HNSC	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.5278
p.S1801L	DO15422	HNSC	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.5278
p.S1801L	SIDM00451	T-Lymphoblastic Leukemia	GDSC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.5278
p.S1801L	PF-382	haematopoietic and lymphoid tissue	COSMIC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.5278
p.S35R	TCGA-DD-AADQ	LIHC	TCGA	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.0556
p.S35R	DO52244	LIHC	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.0556
p.S1994F	TCGA-DJ-A2Q7	THCA	TCGA	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation blocking phosphorylation signal	0.6111
p.S1994F	DO39004	THCA	ICGC	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation blocking phosphorylation signal	0.6111
p.E1129K	TCGA-DK-A2I4	BLCA	TCGA	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.3056
p.E1129K	DO465	BLCA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.3056
p.P1780L	TCGA-EE-A20C	SKCM	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.1667
p.P1780L	DO222775	MELA	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.1667
p.P1780L	DO47665	SKCM	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.1667
p.P1132H	TCGA-EE-A2GH	SKCM	TCGA	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation altering degron motif	0.7694
p.P1132H	DO37643	SKCM	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation altering degron motif	0.7694
p.P1786S	TCGA-EE-A2MG	SKCM	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation altering degron motif	0.6752
p.P1786S	DO37421	SKCM	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation altering degron motif	0.6752
p.G1273D	TCGA-EO-A22R	UCEC	TCGA	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.6087
p.G1273D	DO42713	UCEC	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.6087
p.E2043K	TCGA-FW-A3R5	SKCM	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2043K	TCGA-FW-A3R5	SKCM	TCGA	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2222
p.E2043K	DO228114	EOPC	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2043K	DO228114	EOPC	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2222
p.E2043K	DO37406	SKCM	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944
p.E2043K	DO37406	SKCM	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2222
p.Q2053H	TCGA-IB-7651	PAAD	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.647
p.Q2053H	DO46657	PAAD	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.647
p.S1733C	TCGA-IR-A3LK	CESC	TCGA	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7541
p.S1733C	DO44299	CESC	ICGC	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7541
p.S25L	TCGA-J7-A8I2	KIRP	TCGA	AASTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.8778
p.S25L	DO223958	KIRP	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.8778
p.V1552M	TCGA-KM-8443	KICH	TCGA	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1944
p.V1552M	DO220360	KICH	ICGC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1944
p.T2056A	TCGA-RS-A6TP	HNSC	TCGA	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.3056
p.T2056A	DO219062	HNSC	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.3056
p.P1139R	TCGA-UY-A8OB	BLCA	TCGA	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.2222
p.P1139R	DO219037	BLCA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.2222
p.Y1796H	TCGA-VQ-A8P2	STAD	TCGA	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.6667
p.Y1796H	DO51761	STAD	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation blocking phosphorylation signal	0.6667
p.P526H	TCGA-XF-A9SP	BLCA	TCGA	DLTGQVPTP	DEG_COP1_1	520:528	Mutation altering degron motif	0.7694
p.P526H	DO223598	BLCA	ICGC	DLTGQVPTP	DEG_COP1_1	520:528	Mutation altering degron motif	0.7694
p.G1997C	TCGA-ZF-A9RC	BLCA	TCGA	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation rewiring degron network	0.0833
p.G1997C	DO219068	BLCA	ICGC	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation rewiring degron network	0.0833
p.V1142M	DO230347	COCA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.1389
p.P1271R	DO228106	EOPC	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation altering degron motif	0.7512
p.P1789S	DO234199	ESAD	ICGC	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation altering degron motif	0.6752
p.S29W	DO222469	ESCA	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.2222
p.S2055F	DO222695	ESCA	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.9093
p.T1559M	DO233147	GACA	ICGC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7423
p.L521R	DO233732	GACA	ICGC	DLTGQVPTP	DEG_COP1_1	520:528	Mutation altering degron motif	0.7316
p.R1275C	DO233888	GACA	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275C	SIDM00782	Colorectal Carcinoma	GDSC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275C	ACH-000381	Colon/Colorectal Cancer	CCLE	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R1275C	T84	large intestine	COSMIC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.3056
p.R31C	DO233941	GACA	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.1667
p.S16I	DO228931	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.1944
p.V1142L	DO229028	LICA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation rewiring degron network	0.1389
p.P11S	DO229043	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.0556
p.C2041F	DO229045	LICA	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1389
p.C2041F	DO229045	LICA	ICGC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation rewiring degron network	0.2778
p.G1971D	DO229054	LICA	ICGC	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation rewiring degron network	0.0833
p.S1973N	DO229054	LICA	ICGC	SRRLLDDIS	DEG_APCC_DBOX_1	1980:1988	Mutation blocking phosphorylation signal	0.5833
p.G1548V	DO50771	LICA	ICGC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.0833
p.V1723A	DO228291	MALY	ICGC	PSTSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1389
p.P1261L	DO220902	MELA	ICGC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation rewiring degron network	0.1667
p.M1133I	DO220907	MELA	ICGC	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation altering degron motif	0.6507
p.T2051A	DO232761	PBCA	ICGC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation altering degron motif	0.825
p.P1865S	DO229456	SKCA	ICGC	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation rewiring degron network	0.1111
p.P1865S	DO229456	SKCA	ICGC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation rewiring degron network	0.3056
p.P1865L	DO229456	SKCA	ICGC	LSTPGLE	DEG_SCF_FBW7_2	1851:1857	Mutation rewiring degron network	0.1111
p.P1865L	DO229456	SKCA	ICGC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation rewiring degron network	0.3056
p.I17T	SIDM02059	Colorectal Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.2222
p.S1258P	SIDM00453	Pancreatic Carcinoma	GDSC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation blocking phosphorylation signal	0.5278
p.S1258P	ACH-000023	Pancreatic Cancer	CCLE	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation blocking phosphorylation signal	0.5278
p.S1258P	PA-TU-8988T	pancreas	COSMIC	LEKTPLGE	DEG_SCF_FBW7_2	1267:1274	Mutation blocking phosphorylation signal	0.5278
p.K1874N	SIDM00806	Osteosarcoma	GDSC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation blocking ubiquitination signal	0.5
p.K1874N	ACH-000613	Bone Cancer	CCLE	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation blocking ubiquitination signal	0.5
p.K1874N	ACH-001001	Bone Cancer	CCLE	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation blocking ubiquitination signal	0.5
p.K1874N	HOS	bone	COSMIC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation blocking ubiquitination signal	0.5
p.S1860N	SIDM00487	Colorectal Carcinoma	GDSC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation altering degron motif	0.7069
p.S1860N	ACH-000963	Colon/Colorectal Cancer	CCLE	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation altering degron motif	0.7069
p.S1860N	CCK-81	large intestine	COSMIC	DSGGKT	DEG_SCF_TRCP1_1	1859:1864	Mutation altering degron motif	0.7069
p.V1557M	SIDM00951	T-Lymphoblastic Leukemia	GDSC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7208
p.V1557M	ACH-001737	Leukemia	CCLE	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7208
p.V1557M	ACH-002222	Leukemia	CCLE	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7208
p.V1557M	CTV-1	haematopoietic and lymphoid tissue	COSMIC	VATSS	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7208
p.Y2040C	SIDM01608	Endometrial Carcinoma	GDSC	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation blocking phosphorylation signal	0.5556
p.Y2040C	SIDM01608	Endometrial Carcinoma	GDSC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation blocking phosphorylation signal	0.75
p.Y2040C	ACH-000990	Endometrial/Uterine Cancer	CCLE	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation blocking phosphorylation signal	0.5556
p.Y2040C	ACH-000990	Endometrial/Uterine Cancer	CCLE	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation blocking phosphorylation signal	0.75
p.T2037I	SIDM01659	Kidney Carcinoma	GDSC	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation altering degron motif	0.8189
p.T2037I	ACH-000313	Kidney Cancer	CCLE	PDTST	DEG_SPOP_SBC_1	2035:2039	Mutation altering degron motif	0.8189
p.P1780R	ACH-001395	Breast Cancer	CCLE	PLTPRES	DEG_SCF_FBW7_1	1786:1792	Mutation rewiring degron network	0.1667
p.D1134N	ACH-001568	Skin Cancer	CCLE	PTPMDE	DEG_SCF_FBW7_2	1130:1135	Mutation altering degron motif	0.5821
p.E2060K	ACH-001991	Primary	CCLE	ITRTPQAS	DEG_SCF_FBW7_1	2048:2055	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAP1B

UniProt ID: P46821

Entrez ID: 4131

Protein name: Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAP1B in