DegronMD - P49792(RANBP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P1137S	TCGA-14-1795	GBM	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.2222
p.P1137S	TCGA-OR-A5K9	ACC	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.2222
p.P1137S	DO13114	GBM	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.2222
p.N906S	TCGA-46-3768	LUSC	TCGA	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1111
p.N906S	DO26466	LUSC	ICGC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1111
p.V1404F	TCGA-49-4487	LUAD	TCGA	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.2222
p.V1404F	TCGA-49-4487	LUAD	TCGA	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.1667
p.V1404F	DO24780	LUAD	ICGC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.2222
p.V1404F	DO24780	LUAD	ICGC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.1667
p.M905V	TCGA-85-8479	LUSC	TCGA	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.M905V	DO45443	LUSC	ICGC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.A2442T	TCGA-86-8674	LUAD	TCGA	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.1667
p.A2442T	DO25535	LUAD	ICGC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.1667
p.T1396I	TCGA-98-8021	LUSC	TCGA	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.8189
p.T1396I	DO27468	LUSC	ICGC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.8189
p.D2446Y	TCGA-A5-A2K5	UCEC	TCGA	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.2778
p.D2446Y	TCGA-D1-A17Q	UCEC	TCGA	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.2778
p.D2446Y	DO41903	UCEC	ICGC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.2778
p.D2446Y	DO41379	UCEC	ICGC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.2778
p.S2789Y	TCGA-A5-A2K5	UCEC	TCGA	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.712
p.S2789Y	DO41379	UCEC	ICGC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.712
p.F2790L	TCGA-A8-A09A	BRCA	TCGA	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.587
p.F2790L	DO2955	BRCA	ICGC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.587
p.F2790L	SIDM01242	Melanoma	GDSC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.587
p.F2790L	SIDM01781	Gastric Carcinoma	GDSC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.587
p.F2790L	SIDM01767	Squamous Cell Lung Carcinoma	GDSC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.587
p.V2488I	TCGA-AJ-A3EK	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.0833
p.V2488I	DO41584	UCEC	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.0833
p.R1407Q	TCGA-AP-A056	UCEC	TCGA	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1389
p.R1407Q	TCGA-AP-A056	UCEC	TCGA	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.25
p.R1407Q	DO43971	UCEC	ICGC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1389
p.R1407Q	DO43971	UCEC	ICGC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.25
p.S1422N	TCGA-AP-A0LM	UCEC	TCGA	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation blocking phosphorylation signal	0.6111
p.S1422N	DO43306	UCEC	ICGC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation blocking phosphorylation signal	0.6111
p.S1422N	ACH-000123	Ovarian Cancer	CCLE	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation blocking phosphorylation signal	0.6111
p.S2798Y	TCGA-AX-A05Z	UCEC	TCGA	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation blocking phosphorylation signal	0.5556
p.S2798Y	DO40884	UCEC	ICGC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation blocking phosphorylation signal	0.5556
p.K1152N	TCGA-B5-A1MR	UCEC	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation substituting flanking lysine	0.3333
p.K1152N	DO41758	UCEC	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation substituting flanking lysine	0.3333
p.D1965Y	TCGA-B5-A1MR	UCEC	TCGA	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.0556
p.D1965Y	DO41758	UCEC	ICGC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.0556
p.N1151S	TCGA-BC-A10Q	LIHC	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.25
p.N1151S	DO22887	LIHC	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.25
p.P2505L	TCGA-D3-A1Q6	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.2222
p.P2505L	DO37450	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.2222
p.Q936H	TCGA-D3-A2JP	SKCM	TCGA	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1667
p.Q936H	DO47407	SKCM	ICGC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1667
p.H2452Y	TCGA-D3-A3MV	SKCM	TCGA	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation altering degron motif	0.6118
p.H2452Y	DO37727	SKCM	ICGC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation altering degron motif	0.6118
p.F1134L	TCGA-DX-AB2Q	SARC	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.1389
p.F1134L	DO220087	SARC	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.1389
p.A2507S	TCGA-E6-A1LX	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.1667
p.A2507S	DO41020	UCEC	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.1667
p.P1632L	TCGA-EE-A17X	SKCM	TCGA	VSTPASS	DEG_SCF_FBW7_1	1642:1648	Mutation rewiring degron network	0.0556
p.P1632L	DO37931	SKCM	ICGC	VSTPASS	DEG_SCF_FBW7_1	1642:1648	Mutation rewiring degron network	0.0556
p.S2447F	TCGA-EE-A2M6	SKCM	TCGA	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.75
p.S2447F	DO37976	SKCM	ICGC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.75
p.S2447F	SIDM00127	Oral Cavity Carcinoma	GDSC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.75
p.S2447F	SIDM01567	Hodgkin's Lymphoma	GDSC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.75
p.A1409T	TCGA-EY-A215	UCEC	TCGA	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.0833
p.A1409T	TCGA-EY-A215	UCEC	TCGA	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.3056
p.A1409T	DO42665	UCEC	ICGC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.0833
p.A1409T	DO42665	UCEC	ICGC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.3056
p.P901S	TCGA-GN-A26C	SKCM	TCGA	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.25
p.P901S	DO37782	SKCM	ICGC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.25
p.V2787G	TCGA-GS-A9TV	DLBC	TCGA	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7532
p.V2787G	DO219914	DLBC	ICGC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7532
p.G1136D	TCGA-IB-7651	PAAD	TCGA	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.1944
p.G1136D	DO46657	PAAD	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.1944
p.P1389L	TCGA-LN-A49P	ESCA	TCGA	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1944
p.E1416K	TCGA-ND-A4WC	UCS	TCGA	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation altering degron motif	0.7022
p.P2252R	TCGA-VS-A8QH	CESC	TCGA	VSSSS	DEG_SPOP_SBC_1	2238:2242	Mutation rewiring degron network	0.0556
p.P2252R	DO51630	CESC	ICGC	VSSSS	DEG_SPOP_SBC_1	2238:2242	Mutation rewiring degron network	0.0556
p.T1954I	TCGA-ZM-AA0D	TGCT	TCGA	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation altering degron motif	0.8189
p.S2493L	DO225215	BRCA	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6667
p.S2493L	DO227836	BRCA	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6667
p.S1422G	DO8858	COAD	ICGC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation blocking phosphorylation signal	0.6111
p.M905I	DO222798	COCA	ICGC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.F1961C	DO222285	GACA	ICGC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.1667
p.P918L	DO233281	GACA	ICGC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1111
p.P918L	SIDM00429	B-Lymphoblastic Leukemia	GDSC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1111
p.P918L	ACH-000938	Leukemia	CCLE	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1111
p.P918L	NALM-6	haematopoietic and lymphoid tissue	COSMIC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.1111
p.V2787I	DO233823	GACA	ICGC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7076
p.V2787I	SIDM00217	Colorectal Carcinoma	GDSC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7076
p.V2787I	ACH-000999	Colon/Colorectal Cancer	CCLE	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7076
p.V2787I	SNU-1040	large intestine	COSMIC	TGGTEVMVPSF	DEG_COP1_1	2780:2790	Mutation altering degron motif	0.7076
p.V1141L	DO229019	LICA	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation altering degron motif	0.5654
p.P2505T	DO229030	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.2222
p.P2505T	DO229057	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation rewiring degron network	0.2222
p.T2492A	DO229030	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6389
p.T2492A	HCC-56	large intestine	COSMIC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6389
p.G1138W	DO229036	LICA	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.25
p.G1633C	DO229041	LICA	ICGC	VSTPASS	DEG_SCF_FBW7_1	1642:1648	Mutation rewiring degron network	0.0833
p.F1142C	DO44668	LICA	ICGC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation altering degron motif	0.5996
p.T1954S	DO49150	PACA	ICGC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation altering degron motif	0.7116
p.T923R	DO228523	PRAD	ICGC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation blocking phosphorylation signal	0.6944
p.P2459H	SIDM01943	Colorectal Carcinoma	GDSC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation rewiring degron network	0.1944
p.W1419L	SIDM00330	Neuroblastoma	GDSC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.25
p.W1419L	ACH-001355	Neuroblastoma	CCLE	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.25
p.W1419L	LAN-6	autonomic ganglia	COSMIC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.25
p.H1154L	SIDM01117	Small Cell Lung Carcinoma	GDSC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation rewiring degron network	0.1667
p.V1386F	SIDM00742	Non-Small Cell Lung Carcinoma	GDSC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1111
p.V1386F	ACH-000021	Lung Cancer	CCLE	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1111
p.V1386F	ACH-000033	Lung Cancer	CCLE	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1111
p.V1386F	NCI-H1693	lung	COSMIC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.1111
p.F1961I	SIDM00889	Cervical Carcinoma	GDSC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.1667
p.F1961I	ACH-001333	Cervical Cancer	CCLE	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.1667
p.F1961I	C-33-A	cervix	COSMIC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation rewiring degron network	0.1667
p.V1404I	SIDM00156	Neuroblastoma	GDSC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.2222
p.V1404I	SIDM00156	Neuroblastoma	GDSC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.1667
p.V1404I	NB7	autonomic ganglia	COSMIC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation rewiring degron network	0.2222
p.V1404I	NB7	autonomic ganglia	COSMIC	LVTPKKE	DEG_SCF_FBW7_2	1410:1416	Mutation rewiring degron network	0.1667
p.S1140L	SIDM00637	B-Cell Non-Hodgkin's Lymphoma	GDSC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation blocking phosphorylation signal	0.75
p.S1140L	ACH-000583	Lymphoma	CCLE	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation blocking phosphorylation signal	0.75
p.S1140L	MC116	haematopoietic and lymphoid tissue	COSMIC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation blocking phosphorylation signal	0.75
p.V1141A	SIDM00522	Small Cell Lung Carcinoma	GDSC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation altering degron motif	0.6936
p.V1141A	ACH-000749	Lung Cancer	CCLE	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation altering degron motif	0.6936
p.V1141A	DMS-273	lung	COSMIC	VFGTPTLE	DEG_SCF_FBW7_2	1141:1148	Mutation altering degron motif	0.6936
p.T2492P	SIDM00849	Kidney Carcinoma	GDSC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6389
p.T2492P	SIDM01752	Pancreatic Carcinoma	GDSC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation blocking phosphorylation signal	0.6389
p.S1400N	SIDM00516	Melanoma	GDSC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.818
p.S1400N	ACH-002166	Skin Cancer	CCLE	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.818
p.S1400N	MZ7-mel	skin	COSMIC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.818
p.T2500I	SIDM01088	Endometrial Carcinoma	GDSC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation altering degron motif	0.7078
p.T2500I	SIDM00097	Breast Carcinoma	GDSC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation altering degron motif	0.7078
p.T2500I	SIDM00261	Ewing's Sarcoma	GDSC	VSSTS	DEG_SPOP_SBC_1	2497:2501	Mutation altering degron motif	0.7078
p.S1400R	SIDM01127	Non-Small Cell Lung Carcinoma	GDSC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.8538
p.S1400R	ACH-000628	Lung Cancer	CCLE	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.8538
p.S1400R	NCI-H596	lung	COSMIC	VFTPKTS	DEG_SCF_FBW7_1	1394:1400	Mutation altering degron motif	0.8538
p.K1963I	SIDM00999	Bladder Carcinoma	GDSC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation blocking ubiquitination signal	0.5556
p.K1963I	ACH-000973	Bladder Cancer	CCLE	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation blocking ubiquitination signal	0.5556
p.K1963I	639-V	urinary tract	COSMIC	AKSTS	DEG_SPOP_SBC_1	1951:1955	Mutation blocking ubiquitination signal	0.5556
p.P924L	SIDM00217	Colorectal Carcinoma	GDSC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.2778
p.P924L	ACH-000999	Colon/Colorectal Cancer	CCLE	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.2778
p.P924L	SNU-1040	large intestine	COSMIC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.2778
p.M905T	SIDM00980	Gastric Carcinoma	GDSC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.M905T	ACH-000948	Gastric Cancer	CCLE	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.M905T	23132-87	stomach	COSMIC	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.1389
p.F934L	SIDM01780	B-Cell Non-Hodgkin's Lymphoma	GDSC	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.2222
p.F934L	ACH-000388	Lymphoma	CCLE	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation rewiring degron network	0.2222
p.S2457G	SIDM01611	Endometrial Carcinoma	GDSC	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.6944
p.S2457G	ACH-000996	Endometrial/Uterine Cancer	CCLE	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation blocking phosphorylation signal	0.6944
p.V902G	ACH-000079	Non-Cancerous	CCLE	RPAANVTPT	DEG_SIAH_1	890:898	Mutation rewiring degron network	0.2222
p.I2449V	ACH-000990	Endometrial/Uterine Cancer	CCLE	LITPHVS	DEG_SCF_FBW7_1	2448:2454	Mutation altering degron motif	0.5965
p.V926A	ACH-000993	Endometrial/Uterine Cancer	CCLE	VQSSS	DEG_SPOP_SBC_1	926:930	Mutation altering degron motif	0.5825

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RANBP2

UniProt ID: P49792

Entrez ID: 5903

Protein name: E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RANBP2 in