DegronMD - Q8TAX7(MUC7)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P225T	TCGA-05-4424	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7031
p.P225T	DO23672	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7031
p.T171I	TCGA-17-Z062	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7078
p.T171I	TCGA-D3-A8GL	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7078
p.T171I	DO50287	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7078
p.A274T	TCGA-29-1702	OV	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A274T	TCGA-29-1702	OV	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.0556
p.A274T	DO11441	GBM	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A274T	DO11441	GBM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.0556
p.A274T	DO29528	OV	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A274T	DO29528	OV	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.0556
p.A274T	DO33084	PACA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A274T	DO33084	PACA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.0556
p.A274T	SIDM02057	Colorectal Carcinoma	GDSC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A274T	SIDM02057	Colorectal Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.0556
p.P292S	TCGA-33-A5GW	LUSC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.2778
p.P292S	TCGA-AX-A2HD	UCEC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.2778
p.P292S	DO219122	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.2778
p.P292S	DO42608	UCEC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.2778
p.A213S	TCGA-35-5375	LUAD	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.2778
p.A213S	TCGA-35-5375	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.1389
p.A213S	DO25290	LUAD	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.2778
p.A213S	DO25290	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.1389
p.P307Q	TCGA-43-2578	LUSC	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7035
p.P307Q	DO26662	LUSC	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7035
p.E187Q	TCGA-49-6742	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1944
p.E187Q	TCGA-49-6742	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.E187Q	DO25622	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1944
p.E187Q	DO25622	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.E302Q	TCGA-4Z-AA87	BLCA	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1944
p.E302Q	DO218990	BLCA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1944
p.D270Y	TCGA-50-6593	LUAD	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.25
p.D270Y	TCGA-AX-A05Z	UCEC	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.25
p.D270Y	DO24100	LUAD	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.25
p.D270Y	DO40884	UCEC	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.25
p.A283P	TCGA-53-7626	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.3056
p.A283P	DO23774	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.3056
p.E143D	TCGA-55-1592	LUAD	TCGA	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.2778
p.E143D	DO23556	LUAD	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.2778
p.T189S	TCGA-55-5899	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.25
p.T189S	TCGA-55-5899	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1667
p.T189S	DO26042	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.25
p.T189S	DO26042	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1667
p.S227A	TCGA-55-A4DG	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7588
p.S227A	DO26337	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7588
p.S297Y	TCGA-61-2104	OV	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297Y	TCGA-61-2104	OV	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.S297Y	DO31849	OV	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297Y	DO31849	OV	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.T165A	TCGA-64-5781	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2222
p.T165A	DO23740	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2222
p.A293V	TCGA-69-7979	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.A293V	TCGA-A5-A1OF	UCEC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.A293V	DO23874	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.A293V	DO42568	UCEC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.P232Q	TCGA-91-6828	LUAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1667
p.P232Q	TCGA-91-6828	LUAD	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.25
p.P232Q	DO26150	LUAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1667
p.P232Q	DO26150	LUAD	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.25
p.P170H	TCGA-92-7340	LUSC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.6583
p.P170H	DO26775	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.6583
p.T188A	TCGA-A5-A1OF	UCEC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2222
p.T188A	TCGA-A5-A1OF	UCEC	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1944
p.T188A	DO42568	UCEC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2222
p.T188A	DO42568	UCEC	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1944
p.P254Q	TCGA-A8-A07J	BRCA	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.0556
p.P254Q	TCGA-A8-A07J	BRCA	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1667
p.P254Q	TCGA-A8-A07J	BRCA	TCGA	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.2778
p.P192S	TCGA-AB-2808	LAML	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6752
p.P192S	DO21487	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6752
p.S148T	TCGA-AZ-4315	COAD	TCGA	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation altering degron motif	0.6005
p.S148T	DO8842	COAD	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation altering degron motif	0.6005
p.S149Y	TCGA-AZ-4315	COAD	TCGA	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation altering degron motif	0.712
p.S149Y	DO8842	COAD	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation altering degron motif	0.712
p.A236V	TCGA-B9-A69E	KIRP	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.2778
p.A236V	TCGA-B9-A69E	KIRP	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1389
p.A236V	DO44513	KIRP	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.2778
p.A236V	DO44513	KIRP	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1389
p.E187K	TCGA-BH-A1F8	BRCA	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1944
p.E187K	TCGA-BH-A1F8	BRCA	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.E187K	DO1512	BRCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1944
p.E187K	DO1512	BRCA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.N144Y	TCGA-BP-4161	KIRC	TCGA	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.3056
p.N144Y	DO17769	KIRC	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.3056
p.E302D	TCGA-BS-A0TC	UCEC	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1944
p.E302D	DO42400	UCEC	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1944
p.A191S	TCGA-CC-A123	LIHC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.3056
p.A191S	TCGA-CC-A123	LIHC	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.A191S	DO23038	LIHC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.3056
p.A191S	DO23038	LIHC	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.T175A	TCGA-CG-5721	STAD	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7139
p.T175A	DO38192	STAD	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7139
p.P216T	TCGA-CV-5443	HNSC	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.5919
p.P216T	DO15911	HNSC	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.5919
p.S314F	TCGA-D3-A5GO	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7982
p.S314F	DO47419	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7982
p.S228F	TCGA-D6-6516	HNSC	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7982
p.S228F	DO15623	HNSC	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7982
p.S228F	SIDM00737	Non-Small Cell Lung Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7982
p.S228F	ACH-001362	Lung Cancer	CCLE	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7982
p.S228F	NCI-H1770	lung	COSMIC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.7982
p.S182F	TCGA-D9-A6EC	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	TCGA-EE-A29E	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	TCGA-FR-A729	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	DO37831	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	DO50291	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	DO48618	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	SIDM01175	Other Sarcomas	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	ACH-002309	Sarcoma	CCLE	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S182F	SW684	soft tissue	COSMIC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7982
p.S227P	TCGA-D9-A6EC	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.6752
p.S227P	DO50291	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.6752
p.E233K	TCGA-DA-A1IC	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1944
p.E233K	TCGA-DA-A1IC	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.2222
p.E233K	DO37430	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1944
p.E233K	DO37430	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.2222
p.P215L	TCGA-DA-A95Z	SKCM	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.6471
p.P215L	DO219481	SKCM	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.6471
p.S288F	TCGA-DK-A3IU	BLCA	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation altering degron motif	0.6871
p.S288F	DO612	BLCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation altering degron motif	0.6871
p.P215S	TCGA-DU-A5TW	LGG	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.6752
p.P215S	DO44572	LGG	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.6752
p.P285H	TCGA-E2-A1L7	BRCA	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation altering degron motif	0.6583
p.P285H	DO1937	BRCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation altering degron motif	0.6583
p.A259D	TCGA-E7-A4IJ	BLCA	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.3056
p.A259D	TCGA-E7-A4IJ	BLCA	TCGA	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1389
p.A259D	DO453	BLCA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.3056
p.A259D	DO453	BLCA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1389
p.A190T	TCGA-EA-A410	CESC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2778
p.A190T	TCGA-EA-A410	CESC	TCGA	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1389
p.A190T	DO49929	CESC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2778
p.A190T	DO49929	CESC	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1389
p.P307L	TCGA-EB-A431	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6471
p.P307L	DO37671	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6471
p.A230T	TCGA-EB-A4XL	SKCM	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.0833
p.A230T	TCGA-EB-A4XL	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1111
p.A230T	TCGA-EB-A4XL	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.3056
p.A230T	DO47401	SKCM	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.0833
p.A230T	DO47401	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.1111
p.A230T	DO47401	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.3056
p.P195L	TCGA-EE-A181	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7582
p.P195L	TCGA-EE-A2GJ	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7582
p.P195L	DO37746	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7582
p.P195L	DO37444	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7582
p.S205F	TCGA-EE-A181	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.7982
p.S205F	TCGA-YD-A9TA	SKCM	TCGA	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.7982
p.S205F	DO37444	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.7982
p.S205F	DO219503	SKCM	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.7982
p.S297F	TCGA-EE-A2GO	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297F	TCGA-EE-A2GO	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.S297F	TCGA-EE-A2MR	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297F	TCGA-EE-A2MR	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.S297F	DO37819	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297F	DO37819	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.S297F	DO37823	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.S297F	DO37823	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0556
p.P203S	TCGA-EO-A22U	UCEC	TCGA	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.5641
p.P203S	DO43755	UCEC	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.5641
p.P277L	TCGA-FS-A4FC	SKCM	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.0556
p.P277L	TCGA-FS-A4FC	SKCM	TCGA	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.P277L	DO23158	LINC	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.0556
p.P277L	DO23158	LINC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.P277L	DO37762	SKCM	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.0556
p.P277L	DO37762	SKCM	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1389
p.T175S	TCGA-FX-A3RE	SARC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.6005
p.T175S	DO220122	SARC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.6005
p.S313F	TCGA-GF-A6C9	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6871
p.S313F	TCGA-GN-A8LK	SKCM	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6871
p.S313F	DO229446	SKCA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6871
p.S313F	DO51254	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6871
p.S313F	DO51259	SKCM	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6871
p.A253T	TCGA-HQ-A5ND	BLCA	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.0833
p.A253T	TCGA-HQ-A5ND	BLCA	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A253T	TCGA-HQ-A5ND	BLCA	TCGA	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.3056
p.A253T	DO51899	BLCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.0833
p.A253T	DO51899	BLCA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1389
p.A253T	DO51899	BLCA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.3056
p.S250F	TCGA-L5-A4OT	ESCA	TCGA	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7982
p.P218T	TCGA-LN-A9FP	ESCA	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.7031
p.P307R	TCGA-RD-A7C1	STAD	TCGA	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7512
p.P307R	DO50132	STAD	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7512
p.P218L	TCGA-VQ-A8DL	STAD	TCGA	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.7582
p.P218L	DO51750	STAD	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.7582
p.T245S	TCGA-VS-A8QC	CESC	TCGA	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.T245S	TCGA-VS-A8QC	CESC	TCGA	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.25
p.T245S	DO51628	CESC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.T245S	DO51628	CESC	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.25
p.P261L	TCGA-WS-AB45	COAD	TCGA	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.6471
p.P261L	DO51734	COAD	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.6471
p.P255R	DO225002	BRCA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1944
p.P255R	DO225002	BRCA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.25
p.P298S	DO225336	BRCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1111
p.P298S	DO225336	BRCA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0833
p.P180L	DO225382	BRCA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.6471
p.P180L	DO225381	BRCA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.6471
p.P219S	DO224721	COCA	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.5641
p.P219S	DO218242	GACA	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.5641
p.P177Q	DO222874	COCA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2778
p.P177Q	DO222874	COCA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2778
p.P177Q	DO229051	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2778
p.P177Q	DO229051	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2778
p.P177Q	DO229053	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2778
p.P177Q	DO229053	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2778
p.P177Q	DO22804	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2778
p.P177Q	DO22804	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2778
p.P177Q	DO230545	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.2778
p.P177Q	DO230545	LUSC	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2778
p.T267A	DO222720	ESCA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.7139
p.L249P	DO228612	GACA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.L249P	DO225404	LAML	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.L249P	DO228941	LICA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.L249P	DO228942	LICA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.L249P	DO229053	LICA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.L249P	DO229240	THCA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.6471
p.I308N	DO233888	GACA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.6169
p.N158D	DO233840	GACA	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.0833
p.A237V	DO229346	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO229346	LAML	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO50995	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO50995	LAML	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO225404	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO225404	LAML	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO228941	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO228941	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO229012	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO229012	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO52365	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO52365	LUSC	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A237V	DO52366	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237V	DO52366	LUSC	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.S242P	DO229346	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO225404	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO51020	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO228941	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO229024	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO52364	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.S242P	DO52365	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation altering degron motif	0.5641
p.E279D	DO227501	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.1944
p.S183P	DO227504	LAML	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.6752
p.S183P	DO228584	MALY	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.6752
p.P186Q	DO227504	LAML	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1667
p.P186Q	DO227504	LAML	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.P186Q	ACH-002693	Sarcoma	CCLE	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1667
p.P186Q	ACH-002693	Sarcoma	CCLE	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.S173P	DO228905	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.5641
p.S173P	DO230535	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.5641
p.S173P	DO231040	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.5641
p.P160S	DO228944	LICA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.0833
p.S323P	DO228960	LICA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.0833
p.V157L	DO229041	LICA	ICGC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.1111
p.S229P	DO229052	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.6752
p.T317A	DO50964	LICA	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.25
p.A191V	DO230937	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.3056
p.A191V	DO230937	LUSC	ICGC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.T291I	DO230993	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.3056
p.T291I	DO230990	LUSC	ICGC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.3056
p.P307T	DO231043	LUSC	ICGC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation altering degron motif	0.7031
p.V260A	DO220863	MELA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.6936
p.V260A	DO218872	SKCA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.6936
p.A207V	DO222521	MELA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.0833
p.A207V	DO222521	MELA	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.1111
p.A207V	DO222521	MELA	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.3056
p.P254S	DO222550	MELA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.0556
p.P254S	DO222550	MELA	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.1667
p.P254S	DO222550	MELA	ICGC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.2778
p.P195S	DO222875	MELA	ICGC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6752
p.D270A	DO46374	OV	ICGC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation rewiring degron network	0.25
p.P203L	DO48943	PBCA	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.6471
p.P203L	DO39886	THCA	ICGC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation altering degron motif	0.6471
p.T221N	DO229221	THCA	ICGC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation altering degron motif	0.7055
p.A237D	SIDM02064	Colorectal Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	238:244	Mutation rewiring degron network	0.3056
p.A237D	SIDM02064	Colorectal Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.1111
p.A136D	SIDM02075	Colorectal Carcinoma	GDSC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.0833
p.T137I	SIDM01307	Colorectal Carcinoma	GDSC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.1111
p.A197T	SIDM00620	Glioblastoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.A197T	SIDM00953	Small Cell Lung Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.A197T	SIDM00671	T-Cell Non-Hodgkin's Lymphoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.A197T	SIDM01721	Non-Cancerous	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.A197T	SIDM00191	Kidney Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.A197T	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6028
p.S251F	SIDM00545	Melanoma	GDSC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7982
p.S251F	ACH-000987	Skin Cancer	CCLE	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7982
p.S251F	Mewo	skin	COSMIC	PLSSS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7982
p.D321N	SIDM01090	Colorectal Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00967	Ovarian Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00969	Ovarian Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00087	Plasma Cell Myeloma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00654	Small Cell Lung Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00447	B-Lymphoblastic Leukemia	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM01112	Osteosarcoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00650	Small Cell Lung Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00694	Other Solid Cancers	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00254	Neuroblastoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM01147	Gastric Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00539	Esophageal Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00807	Bladder Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM01133	Other Solid Cancers	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00930	Osteosarcoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM01681	Non-Cancerous	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM00658	Non-Small Cell Lung Carcinoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.D321N	SIDM01173	Rhabdomyosarcoma	GDSC	PITTPNSS	DEG_SCF_FBW7_1	307:314	Mutation rewiring degron network	0.1389
p.P264T	SIDM00965	Small Cell Lung Carcinoma	GDSC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.7031
p.P264T	ACH-000800	Lung Cancer	CCLE	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.7031
p.P264T	NCI-H446	lung	COSMIC	VPPTPSAT	DEG_SCF_FBW7_1	260:267	Mutation altering degron motif	0.7031
p.P169T	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7031
p.P169T	SIDM00032	Bladder Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7031
p.P169T	SIDM01147	Gastric Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7031
p.T176S	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.3056
p.T176S	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.T176S	SIDM00032	Bladder Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.3056
p.T176S	SIDM00032	Bladder Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.T176S	SIDM01147	Gastric Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.3056
p.T176S	SIDM01147	Gastric Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.P226T	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.5919
p.P226T	H513	pleura	COSMIC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation altering degron motif	0.5919
p.P223Q	SIDM01147	Gastric Carcinoma	GDSC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.2778
p.P223Q	SIDM01147	Gastric Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	225:229	Mutation rewiring degron network	0.2778
p.Q200E	SIDM01009	Neuroblastoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2778
p.Q200E	SIDM01009	Neuroblastoma	GDSC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.2778
p.Q200E	ACH-000259	Neuroblastoma	CCLE	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2778
p.Q200E	ACH-000259	Neuroblastoma	CCLE	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.2778
p.Q200E	KELLY	autonomic ganglia	COSMIC	PPTPSAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.2778
p.Q200E	KELLY	autonomic ganglia	COSMIC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.2778
p.T166A	SIDM00902	Non-Small Cell Lung Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.25
p.T166A	ACH-002337	Lung Cancer	CCLE	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.25
p.A178S	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.25
p.A178S	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.3056
p.A178S	ACH-000869	Lung Cancer	CCLE	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.25
p.A178S	ACH-000869	Lung Cancer	CCLE	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.3056
p.A178S	NCI-H1568	lung	COSMIC	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation rewiring degron network	0.25
p.A178S	NCI-H1568	lung	COSMIC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.3056
p.T281R	SIDM00859	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.T281R	Farage	haematopoietic and lymphoid tissue	COSMIC	PPTPSAT	DEG_SCF_FBW7_1	284:290	Mutation rewiring degron network	0.25
p.P180T	SIDM01685	B-Lymphoblastic Leukemia	GDSC	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.5919
p.P180T	ACH-000130	Leukemia	CCLE	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.5919
p.V151A	ACH-000991	Colon/Colorectal Cancer	CCLE	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.2778
p.V151A	SNU-81	large intestine	COSMIC	VNTSS	DEG_SPOP_SBC_1	145:149	Mutation rewiring degron network	0.2778
p.P169Q	ACH-001172	Brain Cancer	CCLE	PPTPSAT	DEG_SCF_FBW7_1	169:175	Mutation altering degron motif	0.7035
p.S181C	ACH-001415	Bladder Cancer	CCLE	PPSSS	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7541
p.P209Q	NCI-H2110	lung	COSMIC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.1667
p.P209Q	NCI-H2110	lung	COSMIC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.25
p.P209Q	SCaBER	urinary tract	COSMIC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.1667
p.P209Q	SCaBER	urinary tract	COSMIC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.25
p.P209Q	NCI-N87	stomach	COSMIC	PPTPPAT	DEG_SCF_FBW7_1	215:221	Mutation rewiring degron network	0.1667
p.P209Q	NCI-N87	stomach	COSMIC	PPSSS	DEG_SPOP_SBC_1	202:206	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC7

UniProt ID: Q8TAX7

Entrez ID: 4589

Protein name: Mucin-7 (MUC-7) (Apo-MG2) (Salivary mucin-7)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC7 in